Report of the status of malaria eradication in the Americas

(1)

regional committee

PAN AMERICAN

HEALTH

ORGANIZATION

XVI Meeting

WORLD

HEALTH

ORGANIZATION

XVII Meeting

Washington, D. C.

September-October 1965

Provisional Agenda Item 11-A

CD16/13 (Eng.)

12 July 1965

ORIGINAL: ENGLISH- SPANISH

A. REPORT ON THE STATUS OF MALARIA ERADICATION

IN THE AMERICAS

XIII REPORT

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TABLE OF CONTENTS

Page

Introduction ... ... 1

I. Status of the Malaria Eradication Program ... 1

A. General Picture ... 1

B. Current Extent of the Problem ... 4

C. Field Operations ... 13

II. Special Technical Problems ... 106

A. General ... 106

B. Evaluation of Methods for Solving Problems of Continuing Transmission ... 106

a) Change to an alternate insecticide ... 106

b) Rescheduling or increasing the cycles of DDT ... 107

C. Anti-larval measures ... 107

D. Mass Drug distribution ... 108

E. Chloroquinized-salt programs ... 110

F. Long-acting repository drugs ... 110

G. Field test of disc flow regulators for spraying ... 111

H. Poor suspensibility of DDT ... 111

I. Stimulation and coordination of operational research ... 111

III. Research on Malaria . . . .. . . . 111

A. Malaria Eradication Epidemiology Team - AMRO-0210 ... . 111

B. Insecticide Testing Team - AMRO-0209 ... 112

C. Resistance of Malaria Plasmodia Strains to Drugs - AMRO-0212 112

IV. International Cooperation .113

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-i-MAPS AND TABLES

Maps: Page

1 Status of the Malaria Eradication Program in the Americas,

31 December 1963 ... 2

2 Status of the Malaria Eradication Program in the Americas,

31 December 1964 ... 3

3 Mass Drug Program in El Salvador ... 109

Tables:

1 Comparison of 1963 and 1964 Population and Area in various phases of the Malaria Eradication Programs in the Americas, and Percentages

of change by phase ... ... 4

2 Progress in Malaria Eradication Programs in the Americas ... 5

3 Status of Malaria Eradication in the Americas, by Population, 1964 . 6

4 Status of Malaria Eradication in the Americas, by Area, 1964 ... 7

5 The Extent and Nature of Problem Areas and remedial Measures taken

and Planned as of December 1964 ... 8

6 Mass Drug Programs in the Americas, 1964 ... 12

7 Personnel Employed in Malaria Eradication Programs in the Americas

31 December 1963 and 1964, by Category ... 14

8 Personnel Employed in Spraying Operations in Malaria Eradication

Programs in the Americas - 31 December 1964 ... 15

9 Personnel Employed in Epidemiological Evaluation in Malaria

Eradication Programs in the Americas - 31 December 1964 ... ; 16

10 Personnel Employed in Administrative and Other Services in Malaria

Eradication Programs in the Americas - 31 December 1964 ... 17

11 Personnel Employed in Transport Services in Malaria Eradication

Programs in the Americas - 31 December 1964 ... . 18

12 Means of Transport in Malaria Eradication Programs in the Americas -1964 ... 20

13 National Budgets for Malaria Eradication in the Americas, 1963-1965 21

14 Comparative Results of Active and Passive Case Detection in Malaria

Eradication Programs in the Americas, 1964 ... 22

15 Summary of Case Detection in the Americas, 1958 - 1964 ... 23

16 PAHO/WHO Full-time Professional and Technical Staff assigned to Country, Inter-Country and Inter-Zone Malaria Eradication Projects

in the Americas, from 1962 to May 1965 ... 114

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-MAPS AND TABLES (Cont.)

Tables: Page

17 Fellowships for study Travel in Malaria Eradication, 1963 and 1964 115

18 Equipment and Supplies, excluding drugs, contributed by PAHO to Malaria Eradication Programs in the Americas, 1958 to December

1964 ... 116

19 Drugs Provided by PAHO to Malaria Eradication Programs in the Americas, 1958-1964 ... 117

20 International Contributions to malaria Eradication Programs in the Americas, 1964 and estimated 1965 ... 118

Country Tables showing the Status of the Malaria Eradication Programs at December 1964: Argentina ... 24

Bolivia ... 27

Brazil (Excl. Sao Paulo) ... 30

Brazil (Sao Paulo) ... 33

Colombia . ... 36

Costa Rica .. ... 39

Cuba ... 42

Dominican Republic ... 45

Ecuador ... 48

El Salvador ... 51

Guatemala ... 54

Haiti .. ... 57

Honduras ... 60

Jamaica ... 63

Mexico ... 65

Nicaragua ... 68

Panama ... 71

Paraguay ... 74

Peru ... 77

Trinidad and Tobago ... 81

Venezuela ... 83

British Guiana ... 86

British Honduras ... 89

Dominica ... 91

French Guiana ... 93

Grenada and Carriacou ... 95

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-MAPS AND TABLES (Cont.)

Page

Guadeloupe. .... ... ... . . .. ... 97

Panama Canal Zone ... ... . ... 99

St. Lucia... . ... ... 101

Surinam ... 103

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-CD16/13 (Eng.) Page 1

REPORT ON THE STATUS OF MALARIA ERADICATION IN THE AMERICAS

XIII REPORT

Introduction

The Director of the Pan American Sanitary Bureau has the honor to present to the XVI Meeting of the Directing Council the XIII Report on the status of malaria eradication in the Americas.

The report consists of four chapters. The first contains information on the status of the program in general and also country-by-country summaries of progress, depicting the history and present condition of each program in tables and graphs. The second chapter discusses special tech-nical problems which have arisen. The third chapter concerns research in malaria currently in progress; the last chapter, international cooperation in malaria eradication programs.

The data presented are taken from the answers by each country to a detailed annual ques-tionnaire and from monthly and quarterly statistical reports submitted to the Pan American Sanitary Bureau by most of the programs, supplemented by data from plans of operation. Special technical reports concerning research projects are also presented when appropriate.

I. STATUS OF THE MALARIA ERADICATION PROGRAMS

A. General Picture

The progress made in 1964 toward eradicating malaria from the Hemisphere cannot be summed up and expressed in a global figure; the situation was complex, with different trends in different regions. In most programs satisfactory progress was made, but in a number of those in Central America and in Mexico, the situation was stationary or deteriorated. Maps 1 and 2 and the summary presented in Table 1 permit comparison of the over-all status at the end of 1964 with that at the end of 1963.

During 1964 two countries completed their consolidation phase and they are in process of receiving certification of the eradication of malaria - Jamaica and Trinidad and Tobago.

The population of consolidation areas shows a decrease compared with December 1963, from 33.9 million persons to 32.3 million. This change is the combined result of the progression of many relatively small areas in various programs from attack to consolidation phase, and the re-gression of areas with about 3.4 million persons from consolidation to attack phase in Mexico, where persistent transmission has resisted attack measures in problem areas and re-infection of previous-ly clean regions has occurred. The countries showing the greatest numbers of persons in areas placed in consolidation during 1964 are Colombia, Honduras, Ecuador, and the State of Sao Paulo in Brazil; a number of other programs shifted areas with smaller populations. In addition to Mexico, programs which were forced to return areas from consolidation to attack included Guatemala, Nica-ragua and Venezuela (NicaNica-ragua also shifted some attack areas into consolidation, with a net gain in population and loss in area in the consolidation phase).

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CD16/13 (Eng.)

Page 2

UNITED STATES

GUATEMALA

.VENEZUELA

FISH

HONDURAS

"o O

BAHAMA ISLANDS

)

CAICOS, TURKS

D

BERMUDA

D BRITISH VIRGIN ISLANDS

/ u. S. VIRGIN ISLANDS

ANGUILLA

/ / ,ST. KITTS, NEVIS

ANTIGUA

/

BARBUDA GUADELOUPE

DOMINICA

C X MARTINIOUE

ST

LUCIA

ST. VINCENT

3---

~

aBARBADOS

--- GRENADA

JM G U A TRINIDAD,

>h-9R. GUIANA TOBAGO

GUIANA

S40 PAULO STATE

N

PARAGUAY

CHI

AREAS IN WHICH MALARIA HAS DISAPPEARED OR NEVER EXISTED

W0

~

f

AREAS WHERE MALARIA HAS BEEN ERADICATED AREAS IN THE CONSOLIDATION PHASE

AREAS WHERE THE CONSOLIDATION PHASE HAS | | NOT BEEN REACHED AND WHERE MALARIA EXISTS

ARGENTINA

STATUS OF THE MALARIA ERADICATION PROGRAM IN THE AMERICAS, 31 DECEMBER

1963.

MAP

I.

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CD16/13

(Eng. )

Page 3

AND CAICOS ISLANDS

)AN6UILLA

)BARBUDA

SH HONDURAS

RITISH GUIANA

N SURINAM

INIDAD AND TOBAGO

ENCH GUIANA

ECUAD

''i

IAI

SIO PAULO STATE

NPARAGUAY

URUGUAY

ZJ

II AREAS IN WHICH MALARIA HAS F= -IDISAPPEARED OR NEVER EXISTED

3

I

AREAS WHERE MALARIA HAS BEEN ERADICATED

---3 AREAS IN THE CONSOLIDATION PHASE

FM

AREAS WHERE THE CONSOLIDATION PHASE HAS NOT BEEN REACHED AND WHERE MALARIA EXISTS

ARGENTINA

Jr

JLV.

STATUS OF THE MALARIA ERADICATION PROGRAM IN THE AMERICAS,

31 DECEMBER 1964.

MAP 2.

NEZUELA

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CD16/13 (Eng.) Page 4

Table 1

COMPARISON OF 1963 AND 1964 POPULATION AND AREA IN VARIOUS PHASES OF THE MALARIA ERADICATION PROGRAMS IN THE AMERICAS,

AND PERCENTAGES OF CHANGE BY PHASE

Phase 1963 1964 Percentage_change

A. Population in thousands:

1. Malaria eradication claimed or registered ... 56 546 57 414 + 1.5

2. Consolidation phase ... 33 901 32 277 - 4.8

3. Attack phase ... 31 910 34 426 + 7.9

4. Preparatory phase or not yet started ... 29 664 34 525 + 16.4

B. Area in km2

1. Malaria eradication claimed or registered ... 2 874 214 2 874 313 + 0.003 2. Consolidation phase ... 2 411815 2 109 589 - 12.5

3. Attack phase ... 3 378 932 3219017 - 4.7

4. Preparatory phase or not yet started ... 7 663 009 7 852 697 + 2.5

For some programs, part of the areas listed in Tables 3 and 4 as in attack phase were actually "in recess", with no active attack measures in progress for lack of funds. Such areas existed in El Salvador, Haiti, Nicaragua and Colombia.

In Haiti, spraying was stopped in large areas including 2.0 million persons and these were placed under intensified surveillance, but were not formally classified as in the consolidation phase.

The area in preparatory phase, or with no program in operation has increased through the addition of some areas in southeastern Colombia,where attack measures have been discontinued. Paraguay still remained entirely in this phase at the end of the year and expects to begin attack operations in the last quarter of 1966. In Argentina, the provinces of El Chaco and Formosa also continued in preparatory phase.

During 1964 administrative problems continued to be the primary hindrance to better progress: technically adequate methods are known for interrupting transmission in most of the areas with persistence, but funds, personnel and efficient administration were frequently lacking. The progress made in improving administration in the Dominican Republic and Colombia continued, the program inBrazil is striving to improve its organization although much remains to be accomplished in this respect. The campaigns in Panama and Central America suffered seriously from the lack of adequate financial resources, as did that in Mexico.

In view of their proximity and the problems they have in common, closer coordination of the various campaigns in Central America and Panama is necessary; PAHO is strengthening its malaria eradication advisory services in Zone III in order to work more effectively in this sphere. Consultations were held during the year to determine the varying legal frameworks of the different countries within which coordinating activities must operate.

B. Current Extent of the Problem

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Table 2

Population in thousands

Year Malaria

I

Annual % of increase

eradication Consolidation

claimed or phase Malaria Consolidation

achieved eradication

claimed

phase

1960 50741 1 991

1961 53 357 13 879 5.2 597.1

1962 55 397 25 914 3.8 86.7

1963 56 546 33 901 2.1 30.8

1964 57 414 32 277 1.5 4.8

In addition to Jamaica and Trinidad and Tobago, which have completed eradication and will receive certification during 1965, the program in Dominica is successfully completing its con-solidation phase. British Honduras, Bolivia. Costa Rica, Cuba, the Dominican Republic, Ecuador, Honduras, Peru and Venezuela are making good progress with their campaigns, despite the exist-ence of some problems and the occurrexist-ence of setbacks in some areas during the year.

Other programs face more serious technical or administrative problems which are still to be overcome. The areas with technical problems are listed in Table 5, which shows the extent of the area and population involved in each country, causes so far discovered for the existence of the problem, the measures which had been applied up to the end of 1964 and the results obtained as of that date.

It should be noted, in reading Table 5. that the remedial measures in operation are, in many programs, less than those which are known to be required. In El Salvador, for example, a program of collective treatment for the population of 166,000 in the Departments of Usulut[n. San Miguel and La Uni6n was planned for 1964 but was not instituted because funds were lacking. In Costa Rica, budgetary difficulties prevented the initiation during 1964 of semi-annual cycles of diel-drin in areas of persistent transmission where excito-repellency of the vector toward DDT is assessed as an important cause and also interrupted the normalprogress of the campaign in both problem and non-problem areas. In Guatemala, supplementary attack with drugs was scheduled for 1964 for 195,000 permanent residents and 154,000 temporary residents in areas of high vector resistance to insecticides, but could be carried out only among 20,000 persons in normal collective-treatment programs and for 19,600 additional persons who were treated by personnel of cotton plantations where they were employed, in a cooperative program of the plantations and the malaria service. During this year of inadequate attack measures, cotton cultivation and the area with DDT-resistant vectors expanded continuously. The adverse effects on the malaria eradication program are appar-ent in the Guatemala country tables relating to epidemiological evaluation operations, to be found on page 56.

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Table 3

STATUS OF MALARIA ERADICATION IN THE AMERICAS, BY POPULATION, 1964 (Population in thousands)

Population of originally malarious areas

Country or other Total Malaria

political unit population a eradication Consolidation Attack or program

Total claimed

(maintenance phase phase not yet

(maintenance started

phase)

Argentina ... 21 480 2 738 1021 627 329 761

Bolivia ... 4 266 1353 - 1141 212

Brazil ... 80 332 40 291 2183 6 289 _{3 1 8 1 9}b

Canada ... 19 272 -

-Chile ... 8 369 134 134 -

-Colombia ... 17 505 9 569 - 6 053 3154 c 362

Costa Rica ... 1 387 423 - 294 129

Cuba ... 7 256 2 239 - - 2 239

Dominican Republic ... 3 452 2 830 - - 2 830

Ecuador ... 4 813 2 652 - 1053 1599

E1 Salvador ... 2828 1900 - 1 900d

Guatemala ... 4 278 1 919 - 1057 862

Haiti ... 4 494 3 533 - - 3 533 e

Honduras ... 2030 1900 - 1631 269

Jamaica ... ... 1706 1365 - 1365

-Mexico ... 39 494 20 212 - 12 740 7 472

Nicaragua ... 1740 1 671 - 695 976f

Panama ... 1 210 1 165 - -1 i65

Paraguay ... 1900 1579 - - - 1579

Peru ... 10794 3 292 43 2 204 1 045

Trinidad and Tobago ... 962 822 - 822

-United States ... 191 300 46 400 46 400

-Uruguay ... 2996 - -

-Venezuela 8... 8 336 6 225 5822 116 287

Antigua ... 60 -

-Bahamas ... 133 -

-Barbados ... 235 231 231

Bermuda ... 48 -

-British Guiana ... 631 631 589 - 42

British Honduras ... 104 104 - 104

-Dominica ... 60 14 - 14

-Falkland Islands ... 2 - -

-French Guiana ... 35 35 - - 31 4

Grenada and Carriacou ... 93 39 39 -

-Guadeloupe ... 298 266 266 -

-Martinique ... 309 192 192 -

-Montserrat ... 13 -

-Netherlands Antilles ... 206 -

-Panama Canal Zone ... 51 51 - 50 1

Puerto Rico ... 2 572 2 556 2556 -

-St. Kitts-Nevis-Anguilla .. 62 -

-St. Lucia ... 99 84 84

-St. Pierre-Miquelon ... 5 - -

-St. Vincent ... 86 -

-Surinam ... 315 190 - 128 62

Virgin Islands (U. K ) .... 8 - -

-Virgin Islands (U. S. ) .... 41 37 37 -

-Total ... 447 666 158 642 57 414 32 277 34 426 34 525

- None

(a) Latest available official figures. (b) Part of this population is partially protected by irregular spraying.

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Table 4

STATUS OF MALARIA ERADICATION IN THE AMERICAS, BY AREA, 1964 (Area in km2)

Originally malarious areas

Country or other Total Malaria

political unit area eradication Consolidation Attacep. phase

Consolidation Attack or program

Total claimed

(masinenance phase phase not yet

(maintenance started

phase)

Argentina ... Bolivia ... Brazil ... Canada ... Chile ... Colombia ... Costa Rica ... Cuba ... Dominican Republic ... Ecuador ... El Salvador ... Guatemala ... Haiti ... Honduras ... Jamaica ... Mexico ... Nicaragua ... Panama ... Paraguay ... Peru ...

Trinidad and Tobago ... United States ... Uruguay ... Venezuela ...

Antigua ... Bahamas ... Barbados ... Bermuda ... British Guiana ... British Honduras ... Dominica ... Falkland Islands ... French Guiana ... Grenada and Carriacou ... Guadeloupe ... Martinique ... Montserrat ... Netherlands Antilles ... Panama Canal Zone ... Puerto Rico.

St. Kitts-Nevis-Angilla .. St. Lucia ...

St. Pierre-Miquelon ... St. Vincent ... Surinam ... Virgin Islands (U. K.) ....

Virgin Islands (U. S. ) ....

Total ...

4 024 458 1 098 581 8 513 861 9974375 741767 1 138 338 51 011 114 524 48442 291 906 21146 108 889 27 750 112088 11 428 1 969 367 139 000 75 650 406752 1 381 800 5 605 9 339 900 186 926 912 050 280 11 396 431 53 215 800 22 696 790 11 961 86000 344 1 779 1 102 84 961 1432 8 896 396 603 240 389 163 820 174 342

41 225 583

349 051 824 260 7445757

55 287 946222 31 526 37 502 39000 175 462 19300 80350 19100 106969 10 028 1 054 775 132 385 69 844 406590 943 200 5 444 2255890

600 000

430

215 800 22696 152 32000 230 1136 300 1 432 8896 510 163750 342 16055616

40 100

55 287

31 040

2255890

469552 f

430 10 600 230 1 136 300 8 896 510 342 2874 313 66963 619 540 190 675 120777 23 281

19198

19 282

97100 10 028 539 731 91799

268 210 5 444

7 681

22696 152

1 432 g

5 600

2109589

- b i S

85922 204 720 363 205

427 281 b 8 245 37 502 39000 156 264 19 _{3 0 0}c 61 068 19 100d 9869 515 044 40586e 69 844 643 950 122767 205 200 32000 (g)

158 150

3219017

156066

6891877a

398 164

406 590

7852697

- None.

(13)

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0t

I Z

qq

Table 5

THE EXTENT AND NATURE OF PROBLEM AREAS AND REMEDIAL MEASURES TAKEN AND PLANNED, AS OF DECEMBER 1964

Insecticide Remedial' Measures

Country and Population Are2)a Vector Causes of Problem

name of area (k) Kid _Kind Years of In operation Planned _Results

coverage in 1964 for 1965

British Guiana

Rupununi 8750 6000 (a) 4 A. darlingi Chloroquine-resistant DDT spraying, 2 1/2 Yr. Continue Good

P. falciparum Rad. treatment,

Pyrime-thamine or quinine for relapses.

Costa Rica

Jicaral-Puntarenas 2 251 223 DDT 7 Known: Excito-repellency to Mass treatment with Substitute DLN Good results in

Matapalo-Aguirre 2 684 266 .". . A. albimanus DDT; peri-domiciliary chloroquine-primaquine spraying semi- Mass Treatment

Puerto Cortes-Osa 1 709 169 " " A. punctimacula biting; open construction bi-weekly; DDT spraying annually for DDT; areas but not all

Sierpe-Osa 1 321 130 " " of houses; internal mi- intra and peri-domicili- Continue Mass areas requiring

Tinoco-Osa 1781 176 Suspected: gration of population. arly. Radical Treat. of and Radical Treat. Treat. included

Golfito 1482 146 pseudo- cases and contacts for lack of funds.

Colorado-Golfito 846 82 punctipennis

Samara-Nicoya 906 89

12 980 1241

El Salvador

Coast 0 to 100 m. Resistance to DDT; DDT spraying Mass treatment No progress in

of Depts. of Excito-repellency to recent years

Usulutan, San Miguel 166 000 1 807 DLN 1 A. albimanus DDT; migration of Pop.

and La Uni6n DDT 8 aggressions to spraying;

new houses. Coast, 0 to 100 m.

of Depts of Ahuacha- 130 000 2'200 DLN 1 . .. DDT spraying; Mass Continue Good

pan, Sonsonate, La DDT 8 Treatment with

Chloro-Libertad, La Paz, quine-Primaquine

bi-San Vicente 296 000 4 007 weekly

General Note: Unless otherwise noted, DDT and DLN sprayings are at standard doses and intervals.

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Table 5 (Cont.)

THE EXTENT AND NATURE OF PROBLEM AREAS AND REMEDIAL MEASURES TAKEN AND PLANNED AS OF DECEMBER 1964

Insecticide Remedial Measures

Country and Area

Country and Population (kie 2a) d Years of Vector Causes of Problem In operation

name of area (kni2) Kind Years of In operation Planned

name ot area

K ind

I

R esults

.overage mn1 1 9 for 1965

Guatemala

Pacific coas, 329 358 6 109 I DLN 2 A. albimanus Resistance to DDT and Mass treatment in cotton Mass Treatment Poor (western 2/3) DDT 6 A. pseudopuncti- DLN; excito-repellency; plantations

pennis (rarely) migration; new houses

Moyutla 12066 310 .. Excito-repellency; DDT; Radic-al T: eat.., Good

migration, new houses mass Treat. 4 months bi-weekly

Jalapa 71069 1 324 ... .. Resistance to DDT and Larviciding in Capital Larvicides Insufficient DLN. internal migratio Distirct

Baja Verapaz 27870 675 .. .... Resistance to DDT and None Larvicides None DLN, internal migration

Alta Verapaz 78 025 2112 .. .... Internal migration; Improved spraying Insufficient

518 388 10 530 open construction of houses

Haiti

Petit-Goave 44 091 200 DDT 2 1/2 A. albimanus Aggresions to spraying; Mass treatment, Chloro- Cont. Mass treat. Too soon to tell habits of population Pyrimethamine 3 week

schedule Honduras

Southern area 132 517 3 682 DDT 4 A. albimanus Resistance to DDT and Malathion in quarterly Mass treatment; Insufficient Mal. 1 1/2 DLN cycles, but interrupted malathion in

and delayed by lack of limited foci funds

Mexico

Tapachula-Suchiate 41 648 1 204 DDT 4 A. albimanus Partial resistance to DDT; Radical treatment. Mass treatment Transmission

DDT and DLN persists

Basin middle 40 596 3 078 .. .. A. pseudopunct. Internal migration; Prompt spraying; s Grijalva river A. albimanus open houses Radical treatment '

(15)

0d 0

aq O_

(D c,

W-an

P

li

Table 5 (Cont. )

Country and |Population (ea2) Vector Causes of Problem

naefara(ki2) K Yiears of IIn operation Planned

name of area Kind _coverage _{in 1964} Results

for 1965

Mexico (Cont. )

North Slope, Sierra Chiapaneca

Isthmus, Gulf slope

Ravine Miguel Alemdn Dam

Upper basin of Papaloapan river Huastecas

Upper basin of Sta. Maria river

Southern Pacific Coast

Basin of the Balsas river and tributaries

Morelos Valley

Coast of Colima and Pihuamo

Coast of Nayarit

Basin of the Santiago river and tributaries

Basin rivers and Pacific coast

albimanus pseudopunct.

..

A. albimanus

A. pseudopunct.

A. albimanus

A. pseudopunct.

A. albimanus A. pseudopunct.

A. pseudopunct.

A. albimanus i. pseudopunct.

Not yet determined

Excito-repellency to DDT, exophagy; new houses

Population movements

Exophagy; new houses

Aggressions; new houses Aggressions because of bed-bugs

Excito-repellency, aggressions;new houses Aggressions (studies in progress)

New houses

Not yet determined

Population movements; new houses

Excito-repellency; exophagy; new houses

Radical treatment

Prompt spraying and radical treatment

Added BHC to DDT

4-month spraying cycles

Prompt spraying

Prompt spraying;

Radical treatment Radical treatment

(a)

All purpose functionaries Larvicides

I . I L

~

, .

Transmission persists

Problem disap-pearing

Improving

Transmission persists

..

(a) A pilot Plan of Integrated Attack including DDT thrice a year, intensive case-detection and 5-day radical treatment with additional measures if necessary, began in October 1964 on the south coast of the Pacific area and will continue. Larviciding and other current measures will be continued.

DDT .. 4 I?? A. A. 238 138 156 662 117736 18 749 579035 23153 950723 1349733 205548 58 426 94 636 96 929 220160 10495 13 467 3 562 1757

12 307

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Table 5 (Cont.)

Country and Population (Kre) _{name of area}_{Years of} Vector _{(Km2) Kind} Causes of Problem

In operation Planned

coverage in 1964 for 1965

Mexico (Cont.)

Basins of Fuerte and 132 908 27 693 DDT 4 A. pseudopunct. People sleep outdoors Radical treatment Transmission

Mayo rivers 4 324 780 290455 persists

Nicaragua

Departments of: 767 051 19 021 DDT 3 or 4 Known: Resistance of A. albi- Malathion; mass treat- Continue Good

Managua Mal. A. albimanus manus to DDT and DLN ment with

chloroquine-Leon pimaquine bi-weekly

Chinandega Suspected:

~~~~~~~~~Madriz

~A.

pseudopunct.

Esteli occasionally

Surinam

Upper Surinam 14 138 ... DLN 2 or 3 A. darlingi Refusal of spraying for Health education; Medicated salt Insufficient

Marowijne 2 954 ... DDT 2 social and religious substitution of DLN beginning in 1966

Tapanahony 5 956 ... reasons; refusals be- for DDT

Lawa 2 356 ... cause of

DDT-resist-ance of cockroachs

25 404

pa 0

,_Pio

Ur (D

(17)

CD16/13- (Eng. ): Page 12

Table 6

MASS DRUG PROGRAMS IN THE AMERICAS, 1964

Population Area Planned

Country trLoceated (K 2) ion Drug Cycle for 1965 measures

Bolivia .... 308 770 Quebrade de Tonina Chloroquine- 2 weeks C DDT spraying

Depto. de Chiquisa- primaquine ca

E1 Salvador 130 000 2 200 Coast of: , . E a DDR spraying,

Ahuachapan, Sonso- larviciding

nate, La Libertad, San Salvador, La Paz, San Vicente

Guatemala 68866 ... Nueva Concepci6n, ." " Eb DDT spraying

Oc6s, Moyutla, cotton plantations

Haiti ... 44091 200 Petit Goave Chloroquine- 3 weeks E _

pyrimetha-mine

Nicaragua 28056 1477 Some localities in Chloroquine- 2 weeks E Malathion

Depts. Madriz, primaquine spraying;

Managua, Chinan- larviciding

dega

Venezuela 116 614 ... . Oriental and "1 week: C Spray;

occidental 85 922 pers.

peri-domi-2 weeks: ciliary;

29094 pers. fogging

1 month: 1 598 pers.

C = To be continued E = To be expanded

(18)

Mexico still faces problems of persistent transmission in areas with over 4.3 million persons. Transmission is at low levels but continues without further reduction. Experiments were made during the year with larviciding and varying schedules of spraying with some success. A program of attack integrating intensified DDT-spraying and case-finding with radical treatment of

all cases was initiated in the problem areas of Oaxaca State on the south coast with financial support from WHO. Complete attack on the problem areas during 1964 was prevented by inadequate financing; it is expected that in 1966 the Government will be able to provide the substantially increased budget required.

In British Guiana, chloroquine-resistant strains of Plasmodium falciparum caused adoption of DDT-spraying in 1962 in an area of the interior, supplementing the chloroquinized-salt program which was the main attack measure. This program achieved good results after an interruption in

early 1963, and cases are now confined to a few foci.

A summary of programs of collective treatment of populations with anti-malarial drugs is presented in Table 6. This attack measure has increased in importance and will undoubtedly play a large role as a complementary method in the future in problem areas with resistant or excitable vectors or a considerable proportion of outdoor biting.

In general, events during 1964 have shown that where technical measures properly adapted to the existing situation are thoroughly applied, satisfactory results are obtained, but that in the absence of adequate attack covering all the areas with transmission combined with good surveillance in all cleared areas, transmission may rise and the work of eradication become longer and more difficult.

C. Field Operations

The personnel engaged in national malaria eradication programs is shown by category of operations and by type of work in Table 7. Tables 8 to 11 show available details of personnelby country.

Spraying operations personnel were slightly more numerous at the end of 1964 thanthey had been at the end of 1963. The increase occurred mainly in Brazil's federal program, where additional areas were brought into attack phase. Honduras also employed more spraying-operations personnel at the end of 1964 than at the end of the preceding year, but this reflects primarily the drop in personnel in late 1963 due to financial difficulties. In El Salvador, spraying cycles were so timed as to take place in only six months of the year, so that there were no spraying personnel at 31 December; spraying was carried on in 1964 and will be continued in 1965. In Haiti, the drop in personnel stems from the cessation of spraying in large areas, discussed above. The decrease in Surinam is an indication of difficulties experienced by the program in the interior of the country, where refusals by the people of the interior to permit spraying increased, for various social reasons, during the year. To overcome some of the objections, operational changes were attempted in order to obtain the cooperation of the people. The most promising one was to hire spraymen in each vil-lage among members of each family group, train them in spraying techniques, supervise their work closely and pay each one according to the number of houses sprayed. The approach is unorthodox, but special approaches must be devised when special populations are being dealt with.

(19)

CD16/13 (Eng.)

Page 14

Table 7

PERSONNEL EMPLOYED IN MALARIA ERADICATION PROGRAMS IN THE AMERICAS

31 DECEMBER 1963 AND 1964, BY CATEGORY

(Part-time personnel in parentheses)

Title

1963

1964

Engineers ...

Spraying Chiefs (non-professionals) ...

Sector Chiefs ...

Squad Chiefs ...

Spraymen ...

Draftsmen ...

SUB-TOTAL ...

Physicians ...

Entomologists ...

Entomologist Assistants ...

Statisticians and Statistician Assistants...

Evaluation Inspectors ...

Evaluators ...

Microscopists ...

SUB-TOTAL ...

Administrators ...

Administrative Assistants ...

Accountants ...

Disbursing Officers ...

Storekeepers .

Assistant Storekeepers ...

Secretaries .

Others .

SUB-TOTAL ...

Transport Chiefs, Mechanics and Assistant

Mechanics

...

Drivers .

Motorboat Operators ...

Boatmen .

SUB-TOTAL ...

GRAND TOTAL .

119(1)

166 (2)

646 (2)

1 923 (2)

9584 (20)

133 12 571 (27)

278 (18)

31 (1)

262 (12)

119 507 (2)

3693 (7)

756(14)

5 646 (54)

317 (1)

947

34

51

96 104 (1)

351 (1)

1852 (56)

3 752 (59)

507 1 464 (2)

223 (2)

36 2 230 (4)

24 199 (144)

117 (1)

208 (2)

662(2)

2 082 (2)

10036 (20)

141 13 246 (27)

271 (13)

21 (1)

247 (12)

139 770 (5) a

4 188 (9) a

747 (15)

6 383 (55)

347 (1)

1 123

38

50

106 93 (1)

351 (1)

1 645 (32)

3 753 (35)

579 1 557 (2)

229 (2)

28 2 393 (4)

25 775 (121)

(a) Includes personnel engaged in mass drug treatment and larviciding.

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(20)

CD16/13 (Eng.) Page 15 Table 8

PERSONNEL EMPLOYED IN SPRAYING OPERATIONS IN MALARIA ERADICATION PROGRAMS IN THE AMERICAS - 31 DECEMBER 1964

(Part-time personnel in parentheses)

Sanitarians

Country or otherl Eieer or Sector Squad Sraymen Draftsmen

political unit Spraying Chiefs Chiefs

-Chiefs

Argentina ... 148 2 6 11 28 96 5

Bolivia a ... 34 1 7 3 3 20

Brazil (Excl.Sao Paulo)b .. 5 334 29 56c 229 800 4 183 37

Brazil (Sao Paulo) ... 606 9 - 33 128 418 18

Colombia ... 706 3 16 54 _{1 3 2}d 487 14

Costa Rica ... 46 1 1 7 8 28 1

Cuba ... 515 1 4 15 74 419 e 2

Dominican Republic ... 527 3 - 14 75 434 1

Ecuador b ... 570 6 - 36 96 431 1

El Salvador ... 3 1 - - - 2

Guatemala ... 335 1 22f 8 46 254 4

Haiti ... 661 6 8 22 96 524 5

Honduras ... 113 - 3 3 16 91

Mexico ... 2446 45 58 117 385 1 818 23

Nicaragua ... 126 - 4 28 15 77 2

Panama ... 257 - 6 10 43 197 1

Paraguay ... 34 2 6 2 18 - 6

Peru ... 303 5 9 34 51 198 6

Trinidad and Tobago ... 30 - - 8 7 12 3

Venezuela ... 331 1 - 20 33 269 8

British Guiana ... 9 1 - - 1 7

French Guiana ... 29 - - 2 7 20

Guadeloupe ... 37 - - 1 6 30

Panama Canal Zone ... (27) (1) (2) (2) (2) (20)

Surinam ... 46 - 2 5 14 23 2

Total 13 246 (27) 117 (1) 208 (2) 662 (2) 2 082 (2) 10 036 (20) 141

- None

(21)

Table 9

PERSONNEL EMPLOYED IN EPIDEMIOLOGICAL EVALUATION IN MALARIA ERADICATION PROGRAMS IN THE AMERICAS - 31 DECEMBER 1964

Country or other Assistant _{Statisticians}and Evaluation

T

Microscopists

politicalunitTotal Physicians Entomologists E ist an n to Evaluators and Laboratory

political unit Entomologists Statisticians' Inspectors

Assistants personnel

Argentina ... 164 9 1 4 2 25 99 24

Bolivia a 123 8 1 4 6 28 61 15

Brazil (excl.Sao Paulo)ub 1782 57 3 24 51 297 1 185 165

Brazil (Sao Paulo) ... 239 12 1 12 1 32 124 57

Colombia ... 496 16 - 7 4 55 377 37

Costa Rica ... 91 1 - - 2 3 72 13

Cuba ... 42 7 1 2 4 3 9 16

Dominican Republic ... 61 2 1 4 6 4 27 17

Ecuador b ... 161 9 1 5 1 - 111 34

E1l Salvador ... 216 5 - 7 4 10 _{17 0}C 20

Guatemala ... .. 144 3 1 19 6 -16 c 77 c 22

Haiti ... 197 8 3 11 9 15 c 109 c 42

Honduras ... 121 2 - 2 1 12 82 22

Jamaica ... 105 2 - 7 - 4 77 15

Mexico .... 988 81 1 33 2 70 _{7 0 6}c 95

Nicaragua ... 224 5 1 6 7 91 c 98c 16

Panama ... 43 2 1 3 4 - . 23 10

Paraguay ... 66 5 1 13 10 2 23 12

Peru ... 209 16 1 6 15 3 126 42

Trinidad and Tobago .... 125 1 - 40 - 1 75 8

Venezuela ... 661 17 2 25 - 71 c 497 c 49

British Guiana ... 24 (1) (1) - - 3 - 16 5

British Honduras ... 12 1 - _ - 2 7 2

Dominica ... 7 (1) (1) - _ _ 1 5 1

French Guiana ... 4 1 1 - 2

Grenada ... 25 (2) - - 10 _ 14 1 (2)

Guadeloupe ... 12 (8) 1 1 1 3 (2) 6 (6)

Panama Canal Zone ... (40) (10) (1) (12) _ (2) (3) (12)

St. Lucia ... 7 (3) (1) - - 4 (1) 3 (1)

Surinam .... ... 34 1 1 4 22 6

Total ... 6 383 (55) 271 (13) 21 (1) 247 (12) 139 770 (5) 4 188 (9) 747 (15)

- None

(a) June. (b) November.

& d a a a b &

(22)

Table 10

PERSONNEL EMPLOYED IN ADMINISTRATIVE AND OTHER SERVICES IN MALARIA ERADICATION PROGRAMS IN THE AMERICAS - 31 DECEMBER 1964

Country or other dminis- A tie DisbursinAccountants Storekeepers Secretaries Others

Total trative Accountants Storekeepers

political unit trators Ai tants Officers Assistants

Assistants

Argentina .... .. 130 4 64 - 4 8 3 [ 47

Bolivia a ... 35 9 5 5 _- - 8 8

Brazil (excl. Sao Paulo) b. 1 596 274 564 23 - 29 - 20 686

Brazil (Sao Paulo) ... 408 15 85 - 9 7 13 - 279 c

Colombia ... 2 235 2 7 - 15 14 8 60 129

Costa Rica ... 17 17 7 - - 2 1 1 5

Cuba ... ... 28 1 4 1 2 5 15

Dominican Republic ... 22 1 3 - - 1 1 5 ! 1

Ecuadorb ... 105 5 13 - 4 6 - 20 57

El Salvador ... 38 1 1 - 1 1 4 8 22

Guatemala ... 36 1 8 - - 3 - 4 20

Haiti ... 109 6 5 3 3 5 3 18 66

Honduras ... 51 1 5 2 - 1 - 15 27

Jamaica ... 9 (1) 2 - - - 1 3 3 (1)

Mexico ... 555 15 236 - 16 15 25 138 110

Nicaragua ... 40 - 5 - - 1 7 8 19

Panama ... 31 1 4 - - 2 9 4 11

Paraguay ... 51 1 25 - - 1 1 7 16

Peru ... 180 1 65 4 1 5 5 15 84

Trinidad and Tobago ... 24 2 15 - - 3 1 2 1

Venezuela ... ...

British Guiana ... 10 - - 1 1 1 7

British Honduras ... 4 1 - - 2 1

Dominica ... 1(1) (1) - - 1

-French Guiana ... 3 - - 1 2

Grenada ... 1(1) 1 - - (1) -

-Guadeloupe ... 3 (26) 1 _- - - 2 (26)

Panama Canal Zone ... (2) _- _ - _ - - (2)

St. Lucia ... (4) _- - - (1) (₃) d

Surinam ... 31 1 2 - 1 2 3 2 20

Total ... 3 753 (35) 347 (1) 1 123 38 50 106 93 (1) 351 (1) 1 645 (32)

... No information. - None

(a) June. (b) November. (c) Includes personnel of Chagas disease control. (d) Spraymen.

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(23)

CD16/13 (Eng. ) Page 18

PERSONNEL EMPLOYED

Table 11

IN TRANSPORT SERVICES IN MALARIA ERADICATION PROGRAMS IN THE AMERICAS - 31 DECEMBER 1964

Transport Chiefs,

Country or other Total Mechanics Drivers Motorboat Boatmen

political unit and operators

Assistant Mechanics

Argentina ...

Boliviaa ...

Brazil (excl. Sao Paulo)b ....

Brazil (Sao Paulo) ...

Colombia ...

Costa Rica ...

Cuba ...

Dominican Republic ...

Ecuador b ...

El Salvador ...

Guatemala ...

Haiti ...

Honduras ...

Mexico ...

Nicaragua ...

Panama ...

Paraguay ...

Peru ...

Trinidad and Tobago .-...

Venezuela ...

British Guiana ...

British Honduras ...

Dominica ...

French Guiana ...

Guadeloupe ...

Panama Canal Zone ....

Surinam ...

Total ...

59 43 1032 250 237 11 13 73 74 41 30 70 40 126 61 9 21 70 30 35 12 3 1 6 6 . (4). 40

2 393 (4)

27 8 246 19 56 2 6 17 12 15 1 30 8 85 2 5 1 18 3 . .. 2 1 2 13 579 32 21

7 4 2c

228 63 9 7 56 62 25 29 39 32 25 51 4 18 29 27 31d 6 1 1 4 4 (2) 11

1 557 (2)

14 38 3 101 1 1 16 8 23 4 3 1 (2) 16

229 (2)

a i i i a

... No information - None.

(a) June. ' (b) November. (c) Includes two airplane pilots. (d) 23 fogging machine operators.

.

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~ ~~

. I I

6

17

2

3

(24)

Some increase occurred in the total number of persons in administration and related ac-tivities, due to increases in Brazil, where the federal program increased its personnel in this cate-gory by several hundred. A number of programs experienced decreases, some, as in Peru, related to re-structuring of zone divisions to meet the current needs of the campaign more economically, without hampering its efficiency.

In transport operations also, an increase in personnel took place which was greatest in the Brazilian federal program. In Peru, increased attention to activities in the Amazon basin region is reflected in the increase in motorboat operators. Venezuela increased the number of operators of machines for insecticidal fogging. Decreases occurred in the transport category in Sao Paulo, El Salvador and Guatemala, and smaller changes in other programs.

Table 12, showing details of means of transport in use in the various programs, shows the increasing use of motorcycles, which have more than doubled in number, and of bicycles which also doubled. _{These changes accompany increasing evaluation operations and drug distribution} programs, which require one-man transport. An increase of almost 20 per cent occurred in the number of motorboats used in the campaigns, while the number of boats without motor, already low, fell further. Venezuela increased the number of fogging machines, used for peridomiciliary fogging of vegetation. _{Means of transport - two-wheeled, four-wheeled, and fluvial - have as usual been} provided promptly by UNICEF in the kinds and quantities recommended by PAHO.

The figures country by country for national budgets for malaria eradication in 1963 and 1964 and amounts committed for 1965 are shown in Table 13. By comparing the amounts actually provided to the programs in 1964 with the amounts committed for that year (shown in last year's report), it can be seen that five countries provided more than originally planned, -these were Argentina, Bolivia, Costa Rica, Honduras and Venezuela, all countries which were experiencing some difficulty either in financing or in technical matters. Four of these, although they had increased their financing above the committed level, were still considered underfinanced. Four programs provided exactly the amount committed; and seven provided very nearly the committed amount, al-though of the seven, six fell slightly short. Among the territories. British Guiana increased the amount of the national malaria budget significantly, while British Honduras and Dominica reduced theirs as a result of progress in their programs. Grenada and Surinam programs received what had been committed.

When commitments for 1965 are compared with amounts provided in 1964, a slight de-crease can be noted. This decrease is more than accounted for by the reduction in the national budget of the federal Brazilian program, for which a new plan of operations has been elaborated ex-tending activities over a somewhat longer period than had been anticipated previously. This exten-sion was required for financial reasons, and is possible within a true eradication program only because the great size of the country permits eradication to be carried out successively region by region.

Programs in South America which made a sizeable increase in their budget commitments in 1965 include Argentina, Bolivia (this would merely restore the total budget to its 1963 level), Co-lombia, Ecuador, Paraguay and Venezuela. Of these programs four were underfinanced in 1964 and three are still considered underfinanced. In the Isthmus of Panama and Central American region, Guatemala and Panama have increased their commitments greatly compared with 1964. Guatemala had increased its budget last year also and the 1965 commitment is double the 1963 budget. In Pana-ma, the 1965 budget will restore the program's funds to the level planned but not actully met in 1964, plus an increase of some 7 per cent. In the Caribbean, Haiti has doubled its commitment (this program, like that of Bolivia in prior years, is primarily externally financed by USAID), Cuba has increased its budget slightly, the Dominican Republic planned to increase its by about 14 per cent, while Jamaica and Trinidad and Tobago, both now finished with their consolidation phase, have reduced their commitments.

(25)

I'dC C(D

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Table 12

MEANS OF TRANSPORT IN MALARIA ERADICATION PROGRAMS IN THE AMERICAS - 1964

Trucks

Country or other Trucks and _Boats _{SadAutomobidle}

political unit (3 tons or "Pick-up" Jeeps station Motorcycles Bicycles Motor without and pack Other

more) (less than _motor _animals

l13 tons) wagons

Argentina ... 10 106 17 13 1 21 -

-Bolivia ... 23 37 2 18 54 35 - 95

Brazil (Excl. Sao Paulo) 54 354 807 34 - 232 150 9 787 2a

Brazil (Sao Paulo) ... 11 158 58 13 - 1 11 - - 2

Colombia ... 16 143 122 37 2 77 153 - 867

Costa Rica ... 1 8 14 3 - 80 11 - (b)

Cuba ... - 36 29 14 - - - - 158

Dominican Republic ... 1 64 15 3 5 c 14 - - 6

Ecuador ... 4 50 37 12 30 10 16 21 326

El Salvador ... 2 49 13 8 48 1 1 -

-Guatemala ... 1 42 14 22 51 40 9 1

-Haiti ... 5 69 13 22 - 2 1 - 16

Honduras ... 2 35 30 7 20 50 1 - 157

Jamaica ... - 14 16 8 - - - -

-Mexico ... 15 436 347 2 9 2 394 d

Nicaragua ... 2 17 34 10 _ 11

-Panama ... - 52 20 8 11 - 20 - (b)

Paraguay ... - 10 15 2 3 2 15 1 12

Peru ... 3 108 66 - - 1 48 13

-Trinidad and Tobago ... 9 9 9 2 - _ _ 1

-Venezuela ... 3 92 72 27 19 314 122 - 560 62e

British Guiana ... - 2 5 4 1

British Honduras ... - 2 8 1 - 3 7 4

-Dominica ... - 3 - 4 - - -

-French Guiana ...

Guadeloupe ... 1 4 6

Panama Canal Zone ... - 2f - - - 2 f

St. Lucia ... _ _ 3

Surinam ... 1 2 5 1 4 6 24

- None.

(a) Airplanes. (b) Rented as needed.

(26)

Table 13

NATIONAL BUDGETS FOR MALARIA ERADICATION IN THE AMERICAS, 1963-1965

(in thousands of U. S. dollars)

National

Country or other National Budget National Budget Commitments

political unit 1963 1964 1965

1965

Argentina ... 520 951 1 392

Bolivia ... - 83 160

Brazil (Excl. Sao Paulo) ... 3 395 11277 8 900*

Brazil (Sao Paulo) ... 1 123 1 242 2 241

Colombia ... .... 2 333 2 333 2 778*

Costa Rica ... 270 264 264

Cuba ... 1 684 1 778 1 861

Dominican Republic ... 772 1 127 1 284

Ecuador ... 685 715 1 045

E1 Salvador ... 366 732 ...

Guatemala ... 452 738 990*

Haiti ... ... 50 50 100

Honduras ... 300 300 300*

Jamaica ... 267 249 167

Mexico ... ... 5 675 6 322 5 974*

Nicaragua a ... .. 453 453 443*

Panama ... 589 518 690*

Paraguay ... 256 258 294*

Peru ... 937 950

Trinidad and Tobago ... 473 470 426

Venezuela ... 3593 3 947 4 296

British Guiana ... ... 39 67 ...

British Honduras ... 33 24 25

Dominica ... .... 9 9 10

French Guiana ... ...

Grenada ... 1 1 1

Guadeloupe ... 147 186 192

Panama Canal Zone ... 50 50 50

St. Lucia ... 5 3 4

Surinam ... 288 301 298

Total ... 24 765 35 398 34 185

- None

... No information

(27)

Table 14

COMPARATIVE RESULTS OF ACTIVE AND PASSIVE CASE DETECTION IN MALARIA ERADICATION PROGRAMS IN THE AMERICAS, 1964

~d

0 P U

aq C_ (DDCD C0

.aq

Active case detection _{Passive case detection}

Blood slides _{Blood slides} _Average

Country or other A _Average Average Average Average of slides_{of slides}

political unit nmeofproduction number of o ocin per month per

political er unit Number Per cent per evaluator notification Number Per cent productive

examined positive per month posts perexamined positive notification

post

Argentina ... 102 152 934 0.1 124.9 1 299 232 28 788 1.4 10.3

Bolivia ... 87 108 097 2.0 103.5 2 545 581 47 443 2.8 6.8

Brazil (excl. Sao Paulo) 1 167 643 911 4.4 46.0 18 829 7 112 597 331 13.5 7.0

Brazil (Sao Paulo) .... 229 454 406 0.1 165.4 4 949 1 768 80 216 1.7 3.8

Colombia ... 302 289 152 1.4 79.8 7 889 4138 210 371 5.0 4.2

Costa Rica ... 67 111721 0.5 138.9 654 141 11 564 5.5 6.8

Cuba ... 9 38 995 0.2 361.1 548 266 237 475 0.2 74.4

Dominican Republic ... 29 87 552 0.2 251.6 1 192 352 33 659 0.4 8.0

Ecuador ... 113 66181 0.3 48.8 4 443 2 280 248 519 1.8 9.1

El Salvador ... 59 95 784 1.9 135.3 2 000 1 656 255 059 9.4 12.8

Guatemala ... 126 178 619 3.0 134.8 2 244 1 104 110439 13.7 8.3

Haiti ... 63 281601 3.0 372.5 2 051 978 191696 5.5 16.3

Honduras ... 64 75769 2.0 98.7 2 238 1101 131 231 3.9 9.9

Jamaica ... 62 55 249 0 74.3 711 82 79 575 0.0 80.9

Mexico ... 323 1 216 462 0.7 313.8 25755 3 977 378 861 1.4 7.9

Nicaragua ... 65 153 836 3.4 197.2 1 692 919 93 775 8.3 8.5

Panama ... 20 55 156 1.1 229.8 1 105 261 76 731 1.6 24.5

Paraguay ... 37 31 072 3.6 70.0 2 605 a 836 a 72 097' 10.7 7.2

Peru ... 119 383 820 0.4 268.8 8 821 1 184 110199 0.5 7.8

United Statesb... 16 0 .... ... ... 90 86.7

Trinidad and Tobago .. 75 28 583 0 31.8 82 82 53455 0.006 54.3

Venezuela c ... 499 248 602 1.1 55.4 2 331 413 125 508 1.5 33.8

British Guiana 16 b 50 253 0.4 261.8 ₇₈b ₂₃ b 4 932 0.3 17.9

British Honduras ... 8 5 255 0.2 54.7 127 71d 6 571 0.3 7.7

Dominica ... 6 8 026 0 111.5 26 21 8 128 0 32.3

French Guiana ... _- - - 16 10 3025 1.6 25.2

Grenada ... 1 517 0 43.1 - -

-Guadeloupe ... 9 21810 0 201.9 ... ... 21 0 ...

Panama Canal Zone ... 3 e 1 147 0 63.7 ... ... 25 081 0.1 ...

St. Lucia. ... 3 13 368 0.03 371.3 - -

-Surinam ... 24 72115 0.6 250.4 54 . 9 4441 28.9 41.1

·.. No information - None

(28)

Table 15

SUMMARY OF CASE DETECTION IN THE AMERICAS, 1958-1964

Number of slides Number of slides Per cent

examined found positive positive

1958 1 716 103 56705 3.3

1959 2 749 117 75 612 2.8

1960 3 955 149 79 998 2.0

1961 5 341004 99 539 1 9

19.62 7 221 367 177 089 2.4

1963 7 903 156 227 026 2 9

1964 8 156 290 254 572 3.1

The Central American countries in which the malaria campaigns face serious technical problems, and Costa Rica where some problem areas also remain, are taking steps to provide con-siderably higher budgets over the next three years. in order to permit their programs to attack the existing problems with thorough, technically-adequate campaigns, in a coordinated manner through-out Central America.

Table 14 sets forth data on active and passive search for cases in each program. It is clear from inspectionof the columns showing per cent of positive smears among those taken in active search and those taken by the passive network that the latter is consistently more productive of cases. This is to be expected since the persons from whom blood-samples are taken by passive search are self-selected as possible malaria cases.

(29)

Country: ARGENTINA Date attack phase began: 1 August 1959

STATUS OF MALARIA PROGRAM AT DECEMBER 1964

Population A km2

(thousands)

TOTAL COUNTRY 21480

Non malarious areas 18 742

Originally malarious areas

Maintenance phase 1 021

- J~~n

_{Consolidation phase}

Attack phase

Preparatory phase

Total originally malarious areas

4 024 458

3 675 407

40 100

627 66963

329 85922

761 156066

2738 349051

PERSONNEL

Activity Professional

f

Non professional

I

Total

Spraying operations 2 146 148

Evaluation operations 11 153 164

Administrative and other - 130 130

Transport - 59 59

Total 13 488 501

TRANSPORT FACILITIES

Type OSpraying Evaluation Mixed or other Total

Operations Operations operations

Four wheel vehicles 53 50 43 146

Two wheel vehicles - 18 4 22

Boats . .

Animals _ _

Other

(30)

ARGENTINA (Cont.)

SPRAYING OPERATIONS

Houses sprayed Inhabitants directly protected Insecticide used Average houses

coverage Planned Sprayed Planned Protected DDT man/day

1st 81619 ₅ 8₄9a 288 768 205189 263

2146b

1st Aug. 59-Jun. 60 81170a ..

2nd 92438 6909b _6909b 347 012 330733 255

3rd 84 011 78487a 323 610 327 209 305

2nd Jul. 60-Jul. 61 6442b

7₄188a

4th 84 077 2 8038b 308142 282178 334

3rd Aug. 61-Jun. 62 5th 81906 2_{3 6 8}052b 303 290 280425 383 6th 96 249 73 027 a 341 780 259 379 349

7th 97 908 63 967 a 351098 229 432 353

4th Jul. 62-Jun. 63 8th 95552 54392a288 182273 329

3 5 0b

9th 90 333 46 627 a 317 972 164 420 320 5th 10th Jul. 63-Jun. 43 572 64 39 430a .135 574 122 685 324 6th Jul. 64-Dec. 64 11th 50 322 44 972 a 172 313 153 995 302 (a) Sprayed twice a year. (b) Sprayed once a year.

1st 2nd 3rd

120 i I V a o t I 360

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~~~~~~~~~~~~~~~~~80

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4th 5th 6th 7th Mth 9th IUth 11tn

Year 1959 1960 1961 1962 1963 1964

l

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7

. Inhabitants to be directly protected

m

Inhabitants directly protected

Houses to be sprayed

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(31)

ARGENTINA (Cont.)

EPIDEMIOLOGICAL EVALUATION OPERATIONS, ATTACK PHASE AREAS

Slides examined _{Species found}

Year of_ _{_}

total Date Total Positive P.

falci-coverage _No. _{P. vivax} _{P. malariae}

parupn

coverage No. Number Percentage parum

Ista Aug. 59-Jun. 60 70700 2497 3.53 6 2491

2ndb Jul. 60-Jul. 61 96991 3880 4.00 4 3876

3rd Aug. 61-Jun. 62 107 926 5 081 4.71 1 5 080

4th Jul. 62-Jun. 63 100 342 1 572 1.56 1 1571 1

5th Jul. 63-Jun. 64 93850 549 0.58 * - 549

6th Jul. 64-Dec.64 53 980 140 0.26 - 140

LTION AND MAINTENANCE PHASE AREAS

10 0

so0

(a) Data for entire country; not separated by attack or consolidation phases. _{(b) Data for attack and consolidation phases, July to December 1960;} attack phase only, January to July 1961.

(32)

Country: BOLIVIA

Date attack phase began: 1 September 1958

Population A km2

(thousands)

TOTAL COUNTRY 4 266 1 098 581

Non malarious areas 2913

-Originally malarious areas

Maintenance phase 0

E11

Consolidation phase

Attack phase

Preparatory phase

274 321

0

1141 619540

212 204720

0 0

Total originally malarious areas 1 353

PERSONNEL

Activity Professional Non-professional Total

Spraying operations 34 34

Evaluation operations 11 112 123

Administrative and other 35 35

Transport 43 43

Total 11 224 235

Spraying Evaluation Mixed or other

Type Operations Operations operationstal

Four-wheel vehicles 23 34 5 62

Two-wheel vehicles - 51 21 72

Boats 12 22 1 35

Animals 60 35 - 95

Other -

-Total 95 142 27 264

824 260

/

I

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(33)

BOLIVIA (Cont.)

SPRAYING OPERATIONS

- None

(a) Includes emergenc 200

o 150

I 100

0

1 50

5.

0

y spraying

800

00

0 Cycle 1st 2nd

Year 119581 - 1959

3rd 4th 5th 6th 1 1960 1 1961

7th 8th 9th

1 1962 1 1963

10th 11th 12th

aq_nm

m

v

pz0

$0

1 1964 1

l/. 71:1 Inhabitants to be directly protected

Inhabitants directly protected

- - - -Houses to be sprayed Houses sprayed

Houses sprayed Insecticide used Average

Year of Inhabitants directly per house houses

total Date DDT Dieldrin protected per housesprayed

coverage per

Cycle Planned Sprayed Cycle Planned Sprayed Planned Protected DDT Dieldrin spray-man/day 1st 131444 116572 st 6 6 10 910 627 362 556190 362 8.3

2nd 148 200 129119 691820 627 210 331 7.0

3rd 147 263 136 601 695 521 634859 319 7.6

2nd 11 331 12268 118

nd 4th Sep. 59-Aug. 60 153 514 142 536 692 274 660185 309 7.2

5th 169 690 159 952 742902 700 295 331 7.6

3rd Sep. 60-Aug. 61 6th 142 210 134173 - 612 356 577 743 329 7.5 Sep. 61-Sep. 62 7th 129 600 124 623 546 005 524 986 353 7.9

4th Sep. 61-Sep. 62 8th 135474 128898 551785 525 005 359 8.6

Oct. 62-Sep. 63 9th 32 561 34469 124 643 131962 408 6.0

10th 32 361 28893 110 578 98 727 428 5.9

6th a Oct. 63-Sep. 64 1th 32 361 32160 123 923 123152 533 5.3

Oct.-Sep. 64 12th 28536 27509 101503 97855 547 5.6

(34)

,--..-BOLIVIA (Cont.)

EPIDEMIOLOGICAL EVALUATION OPERATIONS, ATTACK PHASE AREAS

Slides examined Species found

Year of

_Yetotal

_Date _Positive _P.

falci-total Date Total P. vivax P. malariae

coverage

~coverage

No. No. Number Percentage parumparum

1st Sep. 58-Aug. 59 50980 1843 3.62 273 1 268 302

2nd Sep. 59-Aug. 60 99 241 1 106 1.12 124 803 179

3rd a Sep. 60-Aug. 61 126 384 735 0.58 90 615 30

4th a Sep. 61-Sep. 62 174800 982 0.56 214 758 10

5th a Oct. 62-Sep. 63 165 200 2 026 1.23 803 1 222 1

6th a Oct. 63-Dec. 63 64 913 679 1.05 281 398

6th- 7thb Jan. 64-Dec. 64 88 368 3 315 3.75 477 2838

Date Origin of infections Species of parasite

Estimated _{No. of} % of _Total Imported _nclassi

in the area _Cd _examined

lation

_{itive tochtho-} Relaps- frnm _Induced Intro- _{and no} P. falci-

_{fi_}

P

malar

]4 (thousands) sampled ing from areas duced t parum Piae

1961 1 -4 461 11975 2.6 14 1 1 5 7 - 1 14

1962 1-3 759 18t131 3.2 21 - - 2 19 .- a --1 21

1963 1 - 3 1 179 58 587 7.4 104 18 1 - 73 - 2 10 4 100

-1964 1-4 1141 67172 5.9 139 19 2 4 77 - 16 21 16 121 2

(35)

CD16/13 (Eng) Page 30

Country: BRAZIL (Excl. Sao Paulo) Date attack phase began: August 1959

Population Area km2 (thousands)

TOTAL COUNTRY

'I3

-J Non malarious a Or

Maintenance pha

Consolidation ph

m~ Attack phase

II2

Preparatory ph,

65 332

Lreas 27 801

riginally malarious areas

Lse 0

mase

ase

8 266 622

1 048 880

0

0 0

5712 325865

31819 6891877

Total originally malarious areas 37 531

PERSONNEL

Activity Professional Non-professional Total

Spraying operations 29 5 305 5 334

Evaluation operations 66 1 716 1 782

Administrative and other 61 1 535 1 596

Transport - 1032 1032

Total 156 9588 9 '744

Type Spraying Evaluation Mixed or other

__ _ypeOperations Operations operations ota

Four-wheel vehicles 717 276 256 .1 249

Two-wheel vehicles - 232 - 232

Boats 102 48 9 159

Animals 664 123 - 787

Other - - 2a 2

Total 1 483 679 267 2429

(a) Airplanes

(36)

BRAZIL (Excl. Sao Paulo) (Cont.)

SPRAYING OPERATIONS

Year of Houses sprayed Inhabitants directly protected Insecticide used Average houses

total Date Cycle per house sprayed per

total Datege DDT (g. technical)

spray-Planned Sprayed Planned Protected DDT man/day

(a) Jan. 61-Nov. 61 (a) 820 095 _{8 1 4 4 7 5} 3 399 300 c 3 380 000 c .. .. Jan. 62-Jun.- 62 ... 1622 052 1 350 566 7 016 997 5 843 075 424 ... (a) Jul. 62-Dec. 62 ... 2 292 000 1 960 358 9 724 956 8 317 433 420 ... Jan. 63-Jun. 63 ... 2 062 265 1726 289 8 574 898 7178 751 407 ... (a) Jul. 63-Dec. 63 ... 2 045 534 2 010 035 8 524 558 8 376 676 414 7.5

Jan. 64-Jun. 64 ... 2 532153 1 899 065 10 502 357 7 876 719 412 7.9

L(a)

| Jul. 64-Dec. 64 ... 2 993954 2 350 055 12 310 241 9 662834 419 7.7

NT

~ ~

~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~~~~~~~~~~~.

~

~ ~

~

~ ~

(a) Owing to different spray cycle timing in different regions, these data refer to the calendar year. (b)

3 0 0 0

1

5o

0

CD

Year 2 000 1 800 1 200

8 000 0

6 000 .

4000 X

0

2000

001

60C

0

1961 1962 1963 1964

!!IZiiiiii

i

Inhabitants to be directly protected

\\\\\ Inhabitants directly protected

…Houses to be sprayed

Houses sprayed

Hv 0

p 0

(D C

W

v:

-C.,

(37)

I'd 0

(D M

t

--C4C~

R

;z

Vq

BRAZIL (Excl. S[o Paulo) (Cont.)

EPIDEMIOLOGICAL EVALUATION OPERATIONS, ATTACK PHASE AREAS

Slides examined Species found Year of

total Date Total Positive P.

falci-Total

~~~~~~~~~P.

vivax P. malariae

~coverage

No. Number Percentage parum

(a) Jan. 61-Dec.61 230205 3 6 9 1 2b 16.03 3.620 32 285 2

(a) Jan. 62-Dec. 62 513767 68 371 13.31 22683 45 683 5

(a) Jan. 63-Dec.63 860 681 109 210 12.69 37 502 71 610 98

(a) Jan. 64-Dec.64 1 241 242 109 507 8.82 41 737 67 713 57

(a) Owing to different spray cycle timing in different regions, these data refer (b) Includes 1,005 undifferentiated mixed infections from Espiritu Santo Sector.