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Rev. Bras. Reumatol. vol.50 número4 en v50n4a12

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478 Rev Bras Reumatol 2010;50(4):478

CARTA AOS EDITORES LETTER TO EDITORS

Aos Editores,

Achei muito interessante o relato de caso belamente ilustrado “Um caso de sinovite vilonodular do ombro em adolescente: diagnóstico patológico e por imagem” escrito por Costallat

et al. na edição de janeiro-fevereiro de 2009 da Revista Brasileira de Reumatologia. Gostaria de levantar outra consideração que talvez possa ser discutida, já que nem a ressonância magnética, nem o exame histopatológico foram muito coerentes no que diz respeito à sinovite vilonodular

típica. O texto e as iguras apresentados sugerem um processo inlamatório disseminado sem hemossiderina, macrófagos

espumosos carregados de lipídios e proliferação monótona de

estroma veriicado com certa frequência. As células gigantes

são impressionantes, mas na sinovite reumatoide podem ser vistas na mesma localização mostrada.1 Eu não tenho

conhe-cimento de nenhum relato sobre isso na AIJ.

Você poderia nos dizer mais sobre os achados na cirurgia?

Havia lesões nodulares? Talvez isso só possa ser conirmado

com o tempo, mas a AIJ pode começar em uma articulação e estar associada à presença de anticorpos antinucleares. Certamente, não iria sugerir qualquer mudança no tratamento, mas um acompanhamento cuidadoso pode trazer benefícios.

H. Ralph Schumacher, MD

Professor de Medicina, University of Pennsylvania Divisão de Reumatologia

VA Medical Center, 151K, University & Woodland Aves. Philadelphia, PA 19104  U.S.A. Editor-chefe, JCR: Journal of Clinical Rheumatology Tel: 215-823-4244, Fax: 215-823-6032. E-mail: schumacr@mail.med.upenn.edu Website: http://www.med.upenn.edu/synovium

To the editors

I enjoyed the beautifully illustrated case report “A case of villonodular synovitis of the shoulder in an adolescent: imaging and pathologic diagnosis” by Costallat et al. in the January-February 2009 issue of the Brazilian Journal of Rheumatology. I would like to raise for discussion another possible consideration that might be discussed since neither the MRI nor histopathology was quite consistent with typical

villonodular synovitis. The text and igures shown suggest a very diffuse inlammatory process without the hemosiderin,

foamy lipid laden macrophages and monotonous stromal proliferation often seen. The giant cells are striking but can be seen in precisely the location shown in rheumatoid synovitis.1 I don’t know of any reports of these in JIA.

Can you tell us more about the indings at surgery? Were

there nodular lesions? Perhaps only time will tell but JIA can begin in one joint and JIA can be associated with a positive ANA. Certainly I would not suggest any change in treatment but careful follow-up can be of interest.

H. Ralph Schumacher, MD

Professor of Medicine, University of Pennsylvania Division of Rheumatology

VA Medical Center, 151K, University & Woodland Aves. Philadelphia, PA 19104  U.S.A. Editor-chefe, JCR: Journal of Clinical Rheumatology Tel: 215-823-4244, Fax: 215-823-6032. E-mail: schumacr@mail.med.upenn.edu Website: http://www.med.upenn.edu/synovium

Referência/Reference: 1. Grimley PM, Sokoloff L. Synovial giant cells in rheumatoid arthritis. Am J Pathol 1996; 49:931-954. Collins DH. The pathology of

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Achei muito interessante o relato de caso belamente ilustrado “Um caso de sinovite vilonodular do ombro em adolescente: diagnóstico patológico e por imagem” escrito por Costallat..

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