ABC transporter
Characterisation of an ABC transporter
... that C. glabrata drug resistance occurs as a result of its haploid nature as well as the ability of rapid muta- tion after exposure to azole agents (Safdar et al. 2002). This resistance phenotype can occur due to an ...
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The Nucleotide-Free State of the Multidrug Resistance ABC Transporter LmrA: Sulfhydryl Cross-Linking Supports a Constant Contact, Head-to-Tail Configuration of the Nucleotide-Binding Domains.
... homodimeric ABC NBDs confirmed our previous model- ling [16] predicting they form a rotationally symmetrical dimer containing two identical ATP binding sites, whereby the LSGGQ motif of one monomer binds to ATP ...
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An asymmetric post-hydrolysis state of the ABC transporter ATPase dimer.
... the ABC ATPase, unrestrained MD simulations of the ADP+Pi/apo and ATP/apo states of the isolated NBD dimer of the bacterial ABC transporter MJ0796 were ...
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Novel polymorphisms in plasmodium falciparum ABC transporter genes are associated with major ACT antimalarial drug resistance
... A variation in pfmdr1 gene copy number was also associated with parasite drug susceptibility of artemisinin, mefloquine and lumefantrine.. Our work unveils new candidate markers of P.[r] ...
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Aldehyde dehydrogenase 1 identifies cells with cancer stem cell-like properties in a human renal cell carcinoma cell line.
... Cancer stem cells (CSC) or cancer stem cell-like cells (CSC-LCs) have been identified in many malignant tumors. CSCs are proposed to be related with drug resistance, tumor recurrence, and metastasis and are considered as ...
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Isolation, Characterization and Biological Properties of Membrane Vesicles Produced by the Swine Pathogen Streptococcus suis.
... an ABC transporter), the cell wall-anchored DNase SsnA, the IgM protease Ide, putative exported ribonucleases (G and E), a putative N-acetylmuramoyl-L-alanine amidase, the Plr adhesin ...
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Epibrassinolide regulated synthesis of polyamines and auxins in Raphanus sativus L. seedlings under Cu metal stress
... type ABC transporter by naphthalene acid under heavy metals, hypoxic stress and redox perturbations, was reported by Moons (2003) in rice shoots Results of the present investigation suggest significant ...
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Ovarian cancer stem cells are enriched in side population and aldehyde dehydrogenase bright overlapping population.
... CSCs/CICs could be isolated as ALDH Br cells by the ALDEFLUOR assay [23]. We therefore examined whether CSCs/CICs can be successfully isolated by the ALDEFLUOR assay. MCAS, HTBoA, OVCAR3, OVSAHO and HEC-1 cells were ...
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A novel ABCG-like transporter of Trypanosoma cruzi is involved in natural resistance to benznidazole
... One ABC transporter is over-expressed in BZ-resis- tant strains - The differential gene expression between BZ-resistant and BZ-susceptible strains was initially investigated by the hybridisation of CL ...
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Combination with a defucosylated anti-HM1.24 monoclonal antibody plus lenalidomide induces marked ADCC against myeloma cells and their progenitors.
... MM CSCs have been proposed to be responsible for drug resistance and a relapse although they are not properly defined yet [5]. SP cells are identified as a drug resistant fraction by their ability to efflux a Hoechst ...
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Rev. bras. farmacogn. vol.21 número5
... chemotherapy (Lamping et al., 2010). The pleotropic drug resistant protein Pdr5p is a plasma membrane associated ATP-binding cassette (ABC) transporter and the major multidrug efflux pump of Saccharomyces ...
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Prevalence of Escherichia coli and its virulencerelated genes in a case–control study among children from northeastern Brazil
... In recent years several advances have been made in the determination of EAEC pathogenesis, including the development of in vivo models (Harrington et al., 2009; Roche et al., 2010), and the use of previously ...
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Papel do transportador ABC PRP1 na resistência à pentamidina em Leishmania spp
... The ABC transporter PRP1 would confer resis- tance by sequestering PEN in vesicles that would be exocytosed by the cell throughout the flagellar ...an ABC transporter inhibited by verapamil ...
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Pecuária ABC e COP15
... E ainda há muito a fazer. Os produtores mais avançados da região já alcançam lotação de 3 cabeças por hectare em vários estados da Amazônia Legal. Se todo mundo usasse esta mesma tecnologia, seria possível dobrar o atual ...
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Agricultura de baixa emissão de carbono: quem cumpre as decisões?
... programa ABC, criado pelo Ministério da Agricultura, por meio do qual a verba para as ações do plano ABC chega aos agricultores, não está claramente integrado ao modelo de governança do ...plano ABC, ...
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A conjectura abc- Julio C. Andrade
... Conjectura abc). Em termos simples, a con- jectura abc, diz que se considerarmos 3 n´ umeros inteiros positivos, a, b, c, os quais n˜ ao possuem nenhum fator em comum e satisfazem a + b = c e se denotarmos ...
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UNIVERSIDADE FEDERAL DO ABC
... nuclear, feita a partir de zircônio. Obtido pela fermentação controlada, é utilizado como combustível em veículos urbanos. Problema ambiental associado à mineração do carvão mineral. Tip[r] ...
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RESOURCE CONSUMPTION ACCOUNTING RCA: METODOLOGIA ALTERNATIVA PARA GESTÃO DE CUSTOS
... O nível 6 aumenta substancialmente a precisão das saídas, dos produtos e dos custos padrão da linha de serviço, através do rastreamento das despesas indiretas até às saídas de uma forma que seja mais consistente com o ...
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INTEGRAÇÃO REGIONAL E GESTÃO DOS RECURSOS HÍDRICOS: O PLANO DA BACIA DO ALTO TIETÊ E OS ORGANISMOS DE ARTICULAÇÃO REGIONAL DO GRANDE ABC
... Grande ABC tem uma capacidade governativa e gerencial de elaborar e implantar políticas e ações públicas de gestão e planejamento ambiental, em especial as relacionadas aos recursos hídricos, fomentando o ...
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