CpG-ODN
CpG-ODN Class C Mediated Immunostimulation in Rabbit Model of Trypanosoma evansi Infection.
... C CpG-ODN is relatively stable and has the combined immune effects of both A and B classes of ...of CpG-ODN class C in ...with CpG C and challenged with ...that CpG-ODN ...
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The effect of CpG-ODN on antigen presenting cells of the foal
... Background: Cytosine-phosphate-guanosine oligodeoxynucleotide (CpG-ODN) has been used successfully to induce immune responses against viral and intracellular organisms in mammals. The main objective of this ...
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Proinflammatory Stimulation of Toll-Like Receptor 9 with High Dose CpG ODN 1826 Impairs Endothelial Regeneration and Promotes Atherosclerosis in Mice.
... found that injections with concentrations of 10–500μg per mouse, four times higher than what we used in our experiments, did not produce toxic effects [26]. The time intervals between injections might also be relevant. ...
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Neonate intestinal immune response to CpG oligodeoxynucleotide stimulation.
... with CpG- ODN was high: CCL2, CCL7, CXCL1 and CXCL10 were chosen to compare the efficiency of orally administered CpG- ODN to stimulate intestinal immune responses in neonates and in adult ...
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TGFβ activated kinase 1 (TAK1) at the crossroad of B cell receptor and Toll-like receptor 9 signaling pathways in human B cells.
... Therefore, finally, in order to test if BCR and TLR9 mediated signals act similarly in B cells of healthy individuals and RA patients, the activities of p38 MAPK were compared. The results of phospho-flow experiments ...
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Improving Multi-Epitope Long Peptide Vaccine Potency by Using a Strategy that Enhances CD4+ T Help in BALB/c Mice.
... or CpG-oligodeoxynucleotides (CpG-ODNs) as a Toll-like recep- tor agonist ...and CpG-ODN induced expansion of subpopulations of CD4+ and CD8+ cells producing IFN-γ, the average tumor size in ...
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Antigenicity and Immunogenicity of Plasmodium vivax Merozoite Surface Protein-3
... or CPG ODN 1826, ...in CPG-ODN 1826 also had high antibody titers in comparison to FliC ...in CPG ODN 1826, Quil A, or TiterMax presented antibody titers similar to those of mice ...
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Imunização de camundongos com antígenos de lisado total (NLA) e de excreção-secreção (NcESA) de Neospora caninum associados com oligodeoxinucleotídeo CpG como adjuvante
... vaccination. CpG oligodeoxynucleotides (ODN) have shown to be potent immunoadjuvants for several pathogens, but there is limited information concerning its utilization in vaccination for ...with ...
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Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections.
... of CpG ODN 1826 in exosome immunizations elicited IgG2a and IgG2b antibodies and promoted survival, clearance of parasites and subsequent sterile protection of 83% of the animals challenged with ...
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Efeito imunomodulatório in vivo e in vitro do oligodeoxinucleotídeo CpG na imunização...
... of CpG- containing oligodeoxynucleotides (CpG-ODN) in the neonatal and adult immunization with ovalbumin (OVA) or the extract of house dust mite Blomia tropicalis ...show CpG-ODN is ...
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Pacientes com depressão maior têm menor sensibilidade a contraste visual que indivíduos saudáveis.
... O objetivo foi medir a sensibilidade ao contraste, SC, visual de grades senoidais circulares concêntricas com frequências espaciais de 0,25; 4 e 8 cpg, ciclos por grau de ângulo visual, em adultos saudáveis e com ...
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CpG Improves Influenza Vaccine Efficacy in Young Adult but Not Aged Mice.
... and CpG prior to an IAV challenge showed a clear benefit in regards to clinical symptoms (activity, fur ruffling and weight loss) and mortal- ity compared to unvaccinated ...and CpG which were associated ...
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Caracterização e avaliação das propriedades probióticas de lactococcus lactis NCDO 2118
... ATCC, American Type Culture Collection; CD, Crohn's disease; CpG-DNA, cytosine – phosphate – guanosine DNA; DC, dendritic cell; DNA, deoxyribonucleic acid; dsRNA, doubl[r] ...
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ISSN 0100-879X BIOMEDICAL SCIENCES AND CLINICAL INVESTIGATION
... with ODN or siRNA did not result in a sequence-specific decrease in viability or in inhibition of cell growth (Figure 4), or in sensitization of tumor cells to cisplatin treatment (Figure ...
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Percepção e processamento visual da forma em humanos: filtros de freqüências radiais de 1 e 4 cpg.
... O procedimento de resposta de somação de supra- limiar para cada filtro consistiu na apresentação sucessiva simples do par de estímulos e o voluntário teria que escolher dentre os dois estímulos qual destes continha a ...
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Hipometilação do Promotor de Interleucina-6 Associada com Risco de Doença Arterial Coronariana.
... Resultados: A média do nível de metilação no promotor de IL-6 nos casos de DAC foi significativamente mais baixa do que nos controles (p = 0,023). Análise de regressão logística mostrou associação inversa entre metilação ...
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Poly-thymidine oligonucleotides mediate activation of murine glial cells primarily through TLR7, not TLR8.
... on cytokine production was observed in cells stimulated with both pT-ODNs and CL075 (Fig. 3). Similar results were observed with 5 m M of pT-ODNs in combination with 20 or 100 m M of CL075 Figure 2. mRNA expression by ...
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Virus-like attachment sites and plastic CpG islands:landmarks of diversity in plant Del retrotransposons.
... results showing that there is a higher proportion of U3 att matches than full-length Del elements in the sorghum and maize genomes support this hypothesis. However, we were able to identify a significant number of ...
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Regulation of Active DNA Demethylation by a Methyl-CpG-Binding Domain Protein in Arabidopsis thaliana.
... Active DNA demethylation plays crucial roles in the regulation of gene expression in both plants and animals. In Arabidopsis thaliana, active DNA demethylation is initiated by the ROS1 subfamily of ...
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An integrated inspection of the somatic mutations in a lung squamous cell carcinoma using next-generation sequencing.
... understanding of its etiology may provide therapeutic targets, as is the case in adenocarcinoma [42–45]. We attempted to use a previously identified mutational signature of tobacco exposure [6,26] to assign the smoking ...
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