Cyclosporin A
Cyclosporin A treatment in see childhood psoriasis
... investigated. Cyclosporin A (CysA) is effective in adults with severe psoriasis but there are no extensive data regarding the efficacy and safety of its use in childhood ...
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Optimization of cyclosporin A production by Beauveria nivea in continuous fed-batch fermentation
... of cyclosporin A (Lee and Agathos ...on cyclosporin A production as a precursor (data not ...the cyclosporin A titer continued to increase after cell growth ceased and exogenous L-valine was ...
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Immunotoxic action of cyclosporin A on the humoral immune response of Galleria mellonella pupae
... Cyclosporin A (CsA) was inoculated into the hemocel of pupae in the initial phase of the immune response (at the time of immunization) and in the effector phase of the immune response (within 18 h post ...
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Cyclosporin A-induced new cementum formation: a morphometric evaluation in the periapical region of rats
... Cyclosporin A (CsA) is a potent immunosuppressor used in organ transplantation and in the management of various autoimmune diseases. Recent studies have shown that CsA stimulates deposition of cementum on root ...
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Cyclosporin A preferentially attenuates skeletal slow-twitch muscle regeneration
... with muscle regeneration via NFATc1/GATA2-dependent pathways. However, it is not clear whether calcineurin preferentially affects the regeneration of slow- or fast-twitch muscles. We investigated the effect of a ...
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Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viability.
... The effect of CsA on parasite thermotolerance primed us to investigate the potential interaction between this inhibitor and LmaCyP40, a bifunctional cyclophilin that has both PPIase and co-chaperone function and ...
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The effects of Cyclosporin A and Heteropterys tomentosa on the rat liver
... Cyclosporin A (CsA) is a widely employed immunosuppressive drug that is associated with several side effects, among then hepatotoxicity. Heteropterys tomentosa is a Brazilian plant efficient in reducing damage ...
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Cyclosporin-A does not affect skeletal muscle mass during disuse and recovery
... Regarding muscle phenotype, we observed a consistent slow-to-fast shift in all experi- mental groups (immobilized only, receiving CsA only, and immobi- lized receiving CsA) as compared t[r] ...
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Pesqui. Odontol. Bras. vol.17 número1
... of cyclosporin A (CsA) ad min is tra tion, as so ci ated or not with nifedipine, on the bone loss re sult ing from a lig a ture-in duced periodontitis in ...
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Immunomodulation stimulates the innervation of engineered tooth organ.
... Histology was performed to analyze the development of cultured cell re-associations implanted for two weeks in Nude mice and was compared it to implantations performed in ICR mice [2] and CsA-treated ICR mice (Fig. 5). ...
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J. Appl. Oral Sci. vol.17 número6
... with cyclosporin-A after renal transplantation and to discuss the possible role of type IV collagen in gingival basal lamina as an alternative approach for the diagnosis of ...
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O efeito da ciclosporina-A na osseointegração
... of cyclosporin A is connected with several side-effects, which includes nephrotoxicity, neurological disturbances, hypertension and gingival overgrowth (Faulds et ...of cyclosporin A in association with ...
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Clinics vol.62 número3
... METHODS: Twenty-one male Wistar rats were assigned to 3 groups: control (n = 5), saline (n = 8), and cyclosporin A (n = 8). After 30 days of drug therapy, the rats were killed, and the lungs were removed from the ...
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Pesqui. Odontol. Bras. vol.17 número4
... ABSTRACT: The aim of this study was to evaluate the influence of the administration and withdrawal of cyclosporin A/nifedipine on the bone density in a lateral area adjacent to implants placed in rabbits. Two ...
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Relationship of cyclosporin and sirolimus blood concentrations regarding the incidence and severity of hyperlipidemia after kidney transplantation
... Immunosuppression has been associated with hyperlipidemia after kidney transplan- tation (1,2). While hypertriglyceridemia has been associated with the use of azathioprine (AZA) and steroid (3,4), the combination of ...
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Effects of immunosuppressive drugs on human adipose tissue metabolism
... In the early/mid-1980s, the discovery and introduction of modern IAs into clinical practice was a major breakthrough to prevent and treat allograft rejection, resulting in an improved long-term patient and graft survival ...
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Effects of cyclosporin, nifedipine and phenytoin on gingival myofibroblast transdifferentiation in monkeys
... 15- Ahmed A, Huang L, Raftery AT, Ahmed AK, Fahmy H, El Nahas AM, et al. Cyclosporine A sensitizes the kidney to tubulointerstitial fibrosis induced by renal warm ischemia. Transplantation. 2004;77(5):686-92. 16- Shin ...
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Avaliação morfométrica e estereométrica dos tecidos periodontais de ratos imunossuprimidos por Tracolimus (FK506)
... to cyclosporin A (CsA) and is a potent immunosuppressive agent used as an alternative to CsA to prevent graft rejection and to treatment autoimmune diseases (1, ...
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Arq. Gastroenterol. vol.43 número1
... Treatment with azathioprine was discontinued in one patient because of persistent vomiting and in two others because of pancytopenia. In these cases, cyclosporin was introduced. Standard maintenance therapy for ...
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Effects of long-term cyclosporin therapy on gingiva of rats--analysis by stereological and biochemical estimation.
... Thus, the purpose of the present study was to investigate the level of TGF-β 1 in sa- liva and describe the densities of fibroblasts and collagen fibers in the gingival tissue of rats[r] ...
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