DNA Replication
Multiple regulatory systems coordinate DNA replication with cell growth in Bacillus subtilis.
... initiate DNA replication, it suggested that the observed oriC- independent growth rate regulation might be ...initiates DNA replication using oriN (Figure ...and DNA unwinding (Figures ...
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Separation of DNA replication from the assembly of break-competent meiotic chromosomes.
... pre-mitotic replication profiles for cells of the same genetic background (SK1) using alpha-factor synchronized cultures (Figure 2B and Figure S2, blue ...mitS replication profiles were very similar to ...
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Global profiling of DNA replication timing and efficiency reveals that efficient replication/firing occurs late during S-phase in S. pombe.
... HU-induced DNA replication block ...resumed DNA replication in cells released from a HU-block, we first determined the sites of DNA synthesis in cells treated with 8-mM HU for 3 h ...
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DNA polymerase beta from Trypanosoma cruzi is involved in kinetoplast DNA replication and repair of oxidative lesions
... Specific DNA repair pathways from Trypanosoma cruzi are believed to protect genomic DNA and kine- toplast DNA (kDNA) from ...during DNA replication. In mammals, DNA polymerase ...
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Plasticity of DNA replication initiation in Epstein-Barr virus episomes.
... stretched DNA molecules in the same optical ...genomic DNA of similar size (no hybridization ...the replication forks at the time of the switch from the first to the second labeling ...other ...
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DNA replication is intrinsically hindered in terminally differentiated myotubes.
... of DNA damage in reactivated TD muscle cells, we knocked down, along with p21 and p27, the D3, E1, or A2 ...setting DNA synthesis, as already reported for C2C12 myotubes, critically depends on cyclin ...
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Drosophila Mcm10 is required for DNA replication and differentiation in the compound eye.
... of chromatin structure. Several studies in S. cerevisiae implicate Mcm10 in transcriptional repression of the mating type loci, and link DNA replication proteins to heterochromatin formation [17– 19]. ...
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Modeling inhomogeneous DNA replication kinetics.
... of DNA replication that can be modeled with limited detail ...average replication kinetics than Monte Carlo ...of replication-related quantities. Since average replication kinetics is ...
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Escherichia coli DnaE Polymerase Couples Pyrophosphatase Activity to DNA Replication.
... of DNA elonga- ...to DNA replication in vivo was never ...coli DNA Polymerase III α subunit features pyrophosphatase ...that DNA Polymerases can couple DNA elongation and ...
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Trypanosoma cruzi DNA replication includes the sequential recruitment of pre-replication and replication machineries close to nuclear periphery
... organisms, DNA replication is a complex event involving multiple proteins and enzymes to ensure accurate and timely duplication of the genetic ...the replication origin is recognized by the ...
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Methylation of histone H3 on lysine 79 associates with a group of replication origins and helps limit DNA replication once per cell cycle.
... inactive replication origin, but some H3K79Me2 associated genomic regions did not exhibit strong initiation ...regulating replication in a subset of genomic regions, or it can reflect variations in the use ...
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HTLV-I tax increases genetic instability by inducing DNA double strand breaks during DNA replication and switching repair to NHEJ.
... multiple DNA repair ...during DNA replication in S ...without DNA-PK inhibitor ...with DNA-PK inhibitor for 2 days (middle panel) or 6 days (inhibitor was replenished every 2 ...
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Disruption of mitochondrial DNA replication in Drosophila increases mitochondrial fast axonal transport in vivo.
... expressed in motor neurons using the D42-Gal4 driver, and its axonal transport was assayed in the segmental nerves using time lapse confocal imaging in crawling third instar Drosophila larvae (Figure 9A). Measurement of ...
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Epigenetically-inherited centromere and neocentromere DNA replicates earliest in S-phase.
... a DNA sequence that is both necessary and sufficient for function; whereas, in most other eukaryotes, centromeres are maintained by poorly characterized epigenetic mechanisms in which DNA has a less ...
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Benchmarking pathway interaction network for colorectal cancer to identify dysregulated pathways
... the DNA replication pathway (ID: 281) interacted with three pathways, i) APC/C-mediated degra- dation of cell cycle proteins (ID: 77), ii) regulation of mitotic cell cycle (ID: 850), and iii) mitotic ...
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Virus-Induced Chaperone-Enriched (VICE) domains function as nuclear protein quality control centers during HSV-1 infection.
... It is well established that viruses depend on host molecular chaperones for many aspects of their life cycles (reviewed in [27]). For instance bacteriophage l requires the activities of E. coli DnaK (Hsc70 homologue) and ...
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Chiasmata promote monopolar attachment of sister chromatids and their co-segregation toward the proper pole during meiosis I.
... conserved DNA replication checkpoint factor, which delays cell cycle progression upon DNA replication stress, promotes proper fork progression, and contributes to sister chromatid cohesion in ...
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Intrinsic bent DNA sites in the chromosomal replication origin of Xylella fastidiosa 9a5c
... of DNA nec- essary and sufficient for molecular replication ...prokaryotic replication sites can present conserved structural domains such as curved DNA, which plays an important role in ...
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Modulating chromatin structure and gene expression during African swine fever virus infection : new strategies for an efficient vaccine rational design
... genome replication and ...single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) over a wide range of temperatures, pH values, and salt concentrations and in an ATP-independent manner, with an ...
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ATM and ATR activities maintain replication fork integrity during SV40 chromatin replication.
... chromatin replication suggested the possibility that other checkpoint kinases might also contribute to viral ...hyper-activated DNA-PK (Figure S4B, compare lane 1 with lanes 2–4) ...viral DNA ...
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