Drug screening
Are Peripheral Blood Mononuclear Cells Derived from Patients with Certain Myopathies Suitable for Personalized Drug Screening?
... Background: Limb girdle muscular dystrophies (LGMDs) and several other disorders which share their speciic phenotype are rare, predominantly hereditary conditions with no curative treatment. Differential diagnosis of ...
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In vitro and in vivo experimental models for drug screening and development for Chagas disease
... vivo screening protocols as well as the lack of biomarkers for treating ...in Drug Screening and Development for Chagas Disease, held in Rio de Janeiro, Brazil, on the 25th and 26th of November 2008 ...
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In vitro and in vivo experimental models for drug screening and development for Chagas disease
... and screening protocols to evaluate the trypanocidal activity of a given compound and to the lack of parasitological markers for preclinical ...a drug screening ...
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Trends in protein-based biosensor assemblies for drug screening and pharmaceutical kinetic studies
... enable screening any receptor-ligand ...for drug screening analysis, ensuring a better amplification and enabling the creation of a next generation of ultrasensitive ...
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Optimisation of embryonic and larval ECG measurement in zebrafish for quantifying the effect of QT prolonging drugs.
... toxicity screening is of paramount importance for safe cardiac drug ...preliminary screening for detection of cardiac dysfunction by electrocardiography (ECG) is costly and requires a large number of ...
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Formalization, annotation and analysis of diverse drug and probe screening assay datasets using the BioAssay Ontology (BAO).
... for Drug Discovery Investigations (DDI) [22] describes aspects of drug discovery, but its scope does not include detailed descriptions of biological assays including assay design, biological target, ...
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A portable lipid bilayer system for environmental sensing with a transmembrane protein.
... Planar bilayer lipid membranes (BLMs) have been proposed as a useful platform for various potential applications including single ion channel analysis, drug screening, nanopore sensing at the ...
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Rev. bras. farmacogn. vol.23 número5
... for drug screening with potential effect on the pathogenic relatives Leishmania ...the screening and evaluation of new compounds, due to their physiological similarities with the pathogenic ...
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Cheburator software for automatically calculating drug inhibitory concentrations from in vitro screening assays.
... analysis. Our software, Cheburator, is user friendly, customizable, does not require programming or extensive statistical skills, and comes with detailed documentation. It can also process many text- based data files ...
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Achievement of constitutive fluorescent pLEXSY-egfp
... the drug screening, the compound itself may be able to reduce resazurin, leading to false-positive ...a drug led to cell death or simply led to cell growth arrest because killed cells may pro- duce ...
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Differential in vitro activity of the DNA topoisomerase inhibitor idarubicin against Trypanosoma rangeli and Trypanosoma cruzi
... in drug susceptibility to idarubicin, a drug which displayed substantial trypanocidal activity against ...in drug screening and pre-screening is appeal- ing and may well be useful, ...
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Rev. Bras. Cardiol. Invasiva vol.20 número2 en a03v20n2
... in drug- eluting balloon technology. One is the drug, the other is the balloon catheter, and the last is the excipient that binds the drug to the balloon catheter surface and releases it to the ...
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Guidelines for drug donations
... prevents drug donations from being valued in the recipient country according to the product’s retail price there, which could lead to elevated overhead costs for import tax, port clear- ance, and handling in the ...
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Tyrosine kinase syk non-enzymatic inhibitors and potential anti-allergic drug-like compounds discovered by virtual and in vitro screening.
... of drug-like compounds that could impede the interaction of Syk with its cellular partners while maintaining an active kinase ...the drug-like compound C-13, with promising in vivo anti-allergic ...for ...
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PSA-Screening
... antigen screening after 2012 US Preventive Services Task Force ...cancer screening in men aged 50–69 years (STHLM3): A prospective population-based diagnostic ...
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Braz. J. Pharm. Sci. vol.53 número3
... for drug-likeliness. Drug-likeliness of the shortlisted compounds was defined by mutagenic and carcinogenic properties, RO5, and total polar surface ...the drug-likeliness properties of the top five ...
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Drug abuse prevention
... Considering Resolutions XLI of the XXVII Meeting of the Directing Council, XXV of the XXI Pan American Sanitary Conference, and XVII of the XXIX Meeting of the Dir[r] ...
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AIDS drug treatment
... In addition to reducing mortality, results of the controlled trial showed that zidovudine also signifi- cantly reduced the risk of acquiring an AIDS- defining opportunis[r] ...
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Drug abuse prevention
... Although it may take several years before all the countries have epidemiological surveillance systems to measure the drug abuse problem and monitor its course, it [r] ...
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Drug abuse prevention
... This Institute has prepared a plan of action for the training of resources and the development of registers for the epidemiological surveillance of problems related to drug use in Peru. [r] ...
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