Genetic heterogeneity
Genetic Heterogeneity in Colorectal Cancer and its Clinical Implications
... for genetic diagnosis and the efficacy of targeted ...between genetic heterogeneity and the patients’ ...of genetic heterogeneity in colorectal tumours, its causes and impact on the ...
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Candidate gene linkage analysis indicates genetic heterogeneity in Marfan syndrome
... the genetic heterogeneity of this ...of genetic heterogeneity in MFS by performing linkage analysis of the FBN1 and TGFBR2 genes in 34 families (345 subjects) who met the clinical diagnostic ...
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Genetic heterogeneity of induced pluripotent stem cells: results from 24 clones derived from a single C57BL/6 mouse.
... The genetic heteroge- neity that results from this cloning of individual cells has been addressed in some studies using small numbers of iPSC ...of genetic hetero- geneity that can result from iPSC ...
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It's All about Those Bases: The Need for Incorporating Parasite Genetic Heterogeneity into the Development of Schistosome Vaccines.
... seen in the vaccine literature (e.g., tegument, tetraspanin, glycan, etc.) found that laboratory strains were dramatically over-represented relative to field strains for all Schistosoma mansoni studies and in submitted ...
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Genetic heterogeneity of Escherichia coli strains isolated from raw milk, Minas Frescal cheese, and food handlers
... The genetic pattern of E. coli strains was carried out by pulsed-field gel electrophoresis (PFGE) of restricted DNA, using a CHEF DRII 2 , following the method of Pfaller et al. (1992) with modifications. Briefly, ...
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Genetic heterogeneity of Shiga toxin-producing Escherichia coli strains isolated in São Paulo, Brazil, from 1976 through 2003, as revealed by pulsed-field gel electrophoresis
... Several other virulence factors involved in the pathogenicity of STEC have been described. The intimin encoded by the eae gene, located in the chromosomal locus of enterocyte efface- ment, is responsible for the intimate ...
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CorrectionBraz J Med Biol Res 2011; 44(8): 793-800Candidate gene linkage analysis indicates genetic heterogeneity in Marfan syndrome
... 1 Departamento de Genética e Biologia Evolutiva, Instituto de Biociências, 2 Laboratório de Otorrinolaringologia/LIM32, Hospital das Clínicas, Faculdade de Medicina, Universidade de Sã[r] ...
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Dynamics of hepatitis B virus quasispecies in association with nucleos(t)ide analogue treatment determined by ultra-deep sequencing.
... of genetic information of the ...rare genetic variants of the viruses that cannot be detected using standard direct population sequencing techniques ...abundant genetic heterogeneity of HBV at ...
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Intraclonal protein expression heterogeneity in recombinant CHO cells.
... Therapeutic glycoproteins have played a major role in the commercial success of biotechnology in the post-genomic era. But isolating recombinant mammalian cell lines for large-scale production remains costly and ...
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Arq. NeuroPsiquiatr. vol.57 número2A
... Myotubular/Centronuclear myopathy (CNM) presents a great clinical and genetic heterogeneity. According to the period of onset of the signs and symptoms and degree of muscular involvement, three forms of ...
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Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery.
... the genetic heterogeneity within tumors, which contributes to the observed phenotypic diversity ...Thus, heterogeneity presents a major challenge to optimizing therapeutic regimens, as the targeting ...
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Phylogenetic quantification of intra-tumour heterogeneity.
... intra-tumour genetic heterogeneity (for short: heterogeneity) is now a major focus of cancer genomics research [1–12] due to its potential to provide prognostic information [13–15] and to explain ...
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Rubinstein-Taybi syndrome: a female patient with a de novo reciprocal translocation t(2; 16)(q36.3; p13.3) and dysgranulopoiesis
... 9. Bartholdi D, Roelfsema JH, Papadia F, Breuning MH, Niedrist D, Hennekam RC, et al. Genetic heterogeneity in Rubinstein-Taybi syndrome: delineation of the phenotype of the irst patients carrying mutations ...
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Environmental heterogeneity: Anuran diversity in homogeneous environments
... 2007). However, in this study, the diversity index reflected the environmental heterogeneity. The species richness and diver- sity were directly proportional to the environmental heteroge- neity of the ponds ...
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Dynamic behavior, stochasticity and enviromental heterogeneity in Tribolium castaneum
... high heterogeneity populations ...low heterogeneity populations ...moderate heterogeneity populations ...no heterogeneity populations ...
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Impact of emphysema heterogeneity on pulmonary function.
... Emphysema heterogeneity in COPD subjects significantly contributed to linear regression models of lung function that included overall emphysema (LAA%), HI, age, gender, and smoking ...history. Heterogeneity ...
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Genetic characterization of Brazilian bovine viral diarrhea virus isolates by partial nucleotide sequencing of the 5’-UTR region
... Sul (132 and UFSM3) in 2004. In Paraná State, in 2003, a sister group was observed (303). The isolate 3/4 from State of Mato Grosso do Sul formed a sister-group with the isolates 303, 132, UFSM3, 1/5, EVI006. The results ...
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THEORY AND ANALYSIS OF PARTIAL DIALLEL CROSSES
... it can be concluded that yield-increasing genes have a fre- quency less than 1/2 in the second parental group. In short, the frequency of genes which increase trait expression is approximately 1/2 in group 1 and less in ...
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Drifting fronds and drifting alleles: the genetic architecture of the estuarine seaweed Fucus ceranoides L.
... In CHAPTER II a combination of molecular markers was employed to infer the patterns of genetic exchange between F. ceranoides and two parapatric congeners, and to assess its consequences for the species ...
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Cad. Saúde Pública vol.15 suppl.1
... M olecular epidemiology, predictive genetic tests, and social.. communication of genetic contents.[r] ...
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