HIV drug resistance
Early warning indicators for HIV drug resistance in Cameroon during the year 2010.
... for HIV drug resistance ...of resistance to the limited options of ARVs available within the national context, as it is the case in several resource-limited ...in drug pick-up may be ...
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Incidence and associated factors of HIV drug resistance in Chinese HIV-infected patients receiving antiretroviral treatment.
... National HIV Reference ...chain. HIV viral load and drug resistance mutation tests were performed at the National Center for AIDS/STD Control and Prevention (NCAIDS), China ...Plasma ...
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Brazilian Network for HIV Drug Resistance Surveillance: a survey of individuals recently diagnosed with HIV
... consecutive HIV-positive specimens were collected and genotyped. The HIV drug resistance prevalence can be categorized into three different levels: low (<5%), moderate (5% to 10%), and high ...
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HIV Drug Resistance Surveillance in Honduras after a Decade of Widespread Antiretroviral Therapy.
... pre-ART drug resistance (PDR) to protease inhibitors (PI, pink), nucleoside RT inhibitors (NRTIs, green), non-nucleoside RT Inhibitors (NNRTIs, red), and more than one ARV family (purple) are ...
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HIV drug resistance mutations in proviral DNA from a community treatment program.
... the HIV Stanford Database for Quality Assessment ...hypermutation. HIV-1 PR and RT sequences recovered from PBMC and viral RNA have been submitted to GenBank with the accession numbers KJ69464 to ...
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A combined screening platform for HIV treatment failure and resistance.
... spiked HIV-negative blood plasma, and both rounds of PCR were performed on the ...for resistance associated mutations by entering them into the Stanford University HIV Drug Resistance ...
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Performance of an in-house human immunodeficiency virus type 1 genotyping system for assessment of drug resistance in Cuba.
... monitoring drug resistance in HIV- 1 infected patients ...(ENVA HIV Drug Resistance Typing panels from QCMD (Quality Control for Molecular Diagnostics, Glasgow, UK)) for which ...
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High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen.
... antiretroviral drug treatment history of all children are depicted in Table ...of HIV drug resistance testing after a median of 18 months (IQR 12–24 months) exposure to the current ...ABC- ...
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Molecular characterisation of newly identified HIV-1 infections in Curitiba, Brazil: preponderance of clade C among males with recent infections
... (http://www.ial.sp.gov.br/cgi-bin/ HIV/submissao) was used for subtyping analysis. HIV-1 clade was screened by BLAST (NCBI) and the REGA HIV-1 Subtyping Tool and further characterised by phy- ...
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Tg Ahmad Akram Tg Mohd Ariffina , Rafidah Hanim Shueba
... of HiV-1 subtypes and drug resistance associated mutations in Malaysia were conducted mainly in ...on HiV-1 infected Malaysian children is missing, although HiV drug ...
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Different frequencies of drug resistance mutations among HIV-1 subtypes circulating in China: a comprehensive study.
... other drug resistance mutations were differently among subtypes, sites 41, 69, 101, 106, 179, 190, 210 and 215 were dominant in subtype B, while sites 68, 69, 75, 101, 106, 179, 190, 210, 215 and 238 in ...
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High-levels of acquired drug resistance in adult patients failing first-line antiretroviral therapy in a rural HIV treatment programme in KwaZulu-Natal, South Africa.
... Individuals were recruited at all 17 PHC clinics between December 2010 and March 2012. There were two possible routes for enrolment: i) Routine clinic - adults with virological failure (latest VL .1000 copies/ml) were ...
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Modeling HIV-1 drug resistance as episodic directional selection.
... three HIV-1 datasets obtained from the South African mirror of the Stanford HIV Drug Resistance Database (HIVdb) ...detecting drug resistance would include pre- and post- ...
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Comparisons of Primary HIV-1 Drug Resistance between Recent and Chronic HIV-1 Infection within a Sub-Regional Cohort of Asian Patients.
... Genotypic HIV-1 drug resistance testing was performed locally with externally quality controlled in-house or commercial assays, on samples collected within six months prior to ART ...three ...
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HIV-1 Drug Resistance Mutations: Potential Applications for Point-of-Care Genotypic Resistance Testing.
... Stanford HIV Drug Resistance Database (HIVDB) mutation penalty scoring system was used to identify major NRTI, NNRTI, and PI-resistance mutations and to characterize the level of ...
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J. Pediatr. (Rio J.) vol.85 número2 en v85n2a01
... (NRTI) resistance mutations, particularly T215Y/F, M184V/I and D67N, M41L and K219Q/E, reflecting the widespread exposure to zidovudine and ...had resistance mutations to non-nucleoside reverse tran- ...
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Virologic failure of protease inhibitor-based second-line antiretroviral therapy without resistance in a large HIV treatment program in South Africa.
... Females represented 85% of the patients whose viruses were sequenced, which is slightly higher than the distribution of females commencing second-line ART (75%)[9]. While the demographic and clinical characteristics of ...
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HIV - highlights in drug research.
... O HIV é um vírus e, como tal, é um germe microscópico que, devido a sua incapacidade de auto-reprodução (replicação), precisa infectar uma célula que servirá como hospedeira para a produção de novos ...o ...
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Conservation patterns of HIV-1 RT connection and RNase H domains: identification of new mutations in NRTI-treated patients.
... of HIV-1 RT has shown five positions of the connection domain that interact with DNA (G359, A360, H361, K395 and E396) and a unique position (K390) that interacts with RNA ...within HIV-1 group M (10–70% ...
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Clinical management of children diagnosed with HIV and hepatitis C virus infection
... 9:45 Early versus deferred highly active antiretroviral therapy in HIV infected infants: a European collaborative cohort study Goetghebuer T., Haelterman E., Le Chenadec J., Dollfus C., Gibb D., Boyd K., Judd A., ...
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