Liver cancer
Anti-liver cancer activity in vitro and in vivo induced by 2-pyridyl 2,3-thiazole derivatives
... hydrazine-thiazole derivatives displayed Human dihydroorotate dehy- drogenase inhibition with in vivo anti-arthritic activity and rat liver mi- tochondrial monoamine oxidase inhibition ( Li et al., 2015; Raciti et ...
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Prognostic significance of the neutrophil-to-lymphocyte ratio in primary liver cancer: a meta-analysis.
... Regarding liver cancer, some tumor characteristics have been shown to have prognostic value, including vascular invasion[41] and an increased AFP ...
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Therapeutic mechanism of treating SMMC-7721 liver cancer cells with magnetic fluid hyperthermia
... normal liver tissues, which indicates that Bax is probably an important apoptosis- regulating gene ...gastric cancer, prostate cancer, ovarian cancer, and other tumor cells ...with ...
13
Mechanism of action of novel piperazine containing a toxicant against human liver cancer cells
... in cancer therapy (Ahmed & Van Etten, ...breast cancer and leukemia has been exhibited by piperazine analogues (Yoshida, Maehara & Sugimachi, ...human liver cancer ...
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Possibility of In-House Preparation of Liver Cancer Diagnostic Kits Based on AFP ELISA Test
... Our research was focused on the study of possibility of preparation the AFP Enzyme-Linked Immunosorbent Assay (ELISA) diagnostic kits using tumor marker protein named alpha-fetoprotein (AFP) for hepatocellular carcinoma ...
6
20-years of population-based cancer registration in hepatitis B and liver cancer prevention in the Gambia, West Africa.
... National Cancer Registry of The Gambia (NCR) was established in July ...chronic liver disease, specifically, primary liver cancer and cirrhosis later in adult life ...of cancer during ...
11
Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach.
... in cancer tissues described above, the HBV insertional frequencies in cancer tissues were statistically larger than that in cancer-adjacent tissues (p ...of cancer hepatocytes in liver ...
23
Low density lipoprotein modi fied silica nanoparticles loaded with docetaxel and thalidomide for effective chemotherapy of liver cancer
... In the present study, we successfully developed a docetaxel (DTX) and thalidomide (TDD) co-delivery system based on low density lipoprotein (LDL) modified silica nanoparticles (LDL/SLN/DTX/TDD). By employing the tumor ...
10
Gene silencing of Toll-like receptor 2 inhibits proliferation of human liver cancer cells and secretion of inflammatory cytokines.
... TLR2 Gene by siRNA Inhibits Tumorigenesis in Nude Mice By having established the significant effects of TLR2 knock- down by RNAi in BEL-7402 cells in vitro, we wonder whether TLR2 RNAi would also suppress the ...
7
Deleted in liver cancer 2 (DLC2) was dispensable for development and its deficiency did not aggravate hepatocarcinogenesis.
... in liver cancer 2), a Rho GTPase-activating protein, was previously shown to be underexpressed in human hepatocellular carcinoma and has tumor suppressor functions in cell culture ...of liver tumor ...
9
Liver cancer stem cells are selectively enriched by low-dose cisplatin
... Accumulating evidence has indicated the importance of cancer stem cells in carcinogenesis. The goal of the present study was to determine the effect of low-dose cisplatin on enriched liver cancer ...
5
Editor’s Pick: Non-Alcoholic Fatty Liver Disease – Changing the Prevalence of Liver Cancer?
... fatty liver disease are the two remaining big aetiologies of chronic liver disease in need of better ...fatty liver disease (NAFLD) that has shown the biggest increase in prevalence globally, mostly ...
7
IPA-3 inhibits the growth of liver cancer cells by suppressing PAK1 and NF-κB activation.
... Given that PAK1 has a pivotal role in controlling cell proliferation, the suppression on cell proliferation by IPA-3 could be a result of apoptosis induction. We demonstrated that administration of IPA-3 exhibited a ...
12
Liver cancer-derived hepatitis C virus core proteins shift TGF-beta responses from tumor suppression to epithelial-mesenchymal transition.
... Our study offers relevant observations regarding both the mechanisms of HCV-related carcinogenesis and the impact of TGF-b in human cancer. Indeed, we provide evidence that HCC- derived HCV core proteins alleviate ...
13
“Primum Non Nocere” in Interventional Oncology for Liver Cancer
... Another dreaded potential complication is infection. Ablation is classified as a “clean-contaminated” procedure, that is, a procedure performed without active inflammation that does not compromise sterility, with limited ...
13
Liver fluke induces cholangiocarcinoma.
... malignant liver cancers are of two main histologic types distinguished by their cellular ...the liver, and is the most common form of liver cancer throughout the ...of liver ...
8
Cytotoxicity of Marchantia convoluta leaf extracts to human liver and lung cancer cells
... and liver carcinoma (HepG2) cell lines was ...and liver cancer cell cultures with varying concentrations of extracts (15 to 200 µg/mL), cytotoxicity was determined by the 3-(4,5-dimethylthiazol- ...
8
Carcinoma after liver transplantation.
... The number of organ transplantation has increasing worldwide. Several authors have reported an increase in cancer incidence in these patients. There is a marked increase of a variety of tumors. However, common ...
2
Epidemiology of Acute Liver Failure from a Regional Liver Transplant Center in Portugal
... Background and Aims: Acute liver failure (ALF) is a rare dis- ease with potentially high mortality rates. We aimed to study the recent epidemiology of ALF in one of the Portu- guese liver transplant (LT) ...
7
Fatty Liver and Autoimmune Hepatitis: Two Forms of Liver Involvement in Lipodystrophies
... a liver with normal echogenicity and dimensions and a discrete homogeneous ...splenomegaly. Liver histology re- vealed a portal fibrous mass with partial nodular transformation, ...
8