Non-small cell carcinoma
Experimental study of peripheral-blood pro-surfactant protein B for screening non-small cell lung cancer
... expressions of surfactant proteins and vascular endotheli-al growth factors in lung cancer patients and healthy people, and found that the above two indicators are clearly overexpressed in lung cancer, and higher in ...
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High-density lipoprotein cholesterol is a favorable prognostic factor and negatively correlated with C-reactive protein level in non-small cell lung carcinoma.
... Several small molecule tyrosine kinase inhibitors (TKIs) such as the anti-EGFR targeted drug gefitinib and erlotinib have been tested in clinical trials with some clinical success in lung cancer ...
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Predictive significance of standardized uptake value parameters of FDG-PET in patients with non-small cell lung carcinoma
... F– –fluoro-2-deoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) is widely used to diagnose and stage non-small cell lung cancer (NSCLC). The aim of this retrospective ...
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HOXA5 inhibits metastasis via regulating cytoskeletal remodelling and associates with prolonged survival in non-small-cell lung carcinoma.
... for cell adhesion, migration, and polarity ...controls cell polarity, invasion, and actin cytoskeleton organisation ...A549 cell motility and in- vasiveness were decreased via c-Crk dephosphorylation ...
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Watermelon Stomach, Hemorrhagic Pericarditis, Small Cell Carcinoma of the Lung and Synchronous Squamous Cell Carcinoma of the Tongue Base
... on culture. No malignant cells found. Up- per gastrointestinal endoscopy to explain dysphagia showed a normal esophagus, but revealed typical aspects of GAVE (Fig. 2). We were unable to confirm it histologically through ...
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MicroRNA-dependent regulation of transcription in non-small cell lung cancer.
... a small set of nine gene-signatures, in which ABCC3 is included, has been recently proposed for sub-classification of NSCLC ...adeno- carcinoma than in SCC and found that the expression of this gene may be ...
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Inhibitory Activity of (+)-Usnic Acid against Non-Small Cell Lung Cancer Cell Motility.
... Hepatotoxicity of usnic acid may restrict their potential medicinal use in cancer therapeutics [28]. However, most of hepatotoxicity in human was observed when high dose of usnic acid was orally administrated as a ...
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Non-small cell lung cancer in never smokers: a clinical entity to be identified
... squamous cell carcinoma (SCC), adenocarcinoma and other types of carcinoma (large-cell carcinoma, poorly or undifferentiated carcinoma and not otherwise specified ...
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The Clinical Activity of PD-1/PD-L1 inhibitors in Metastatic Non-Clear Cell Renal Cell Carcinoma
... Unlike ccRCC, where the initiating oncogenic event has been attributed to VHL gene inactivation (6), driver mutation events of distinct nccRCC entities are heterogeneous (7 –10). The diversity of this population and the ...
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Identification of novel deregulated RNA metabolism-related genes in non-small cell lung cancer.
... cancer cell lines stimulated with insulin-like growth factor ...colon carcinoma, and lymphoma, suggesting an association of this protein with high cell division rates ...lular carcinoma [48], ...
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Immune checkpoint inhibitors for advanced non-small cell lung cancer: emerging sequencing for new treatment targets
... as non-platinum based single agents like paclitaxel, docetaxel, gemcitabine, vinorelbine and irinotecan have improved the median survival to 7–9 months and 1-year survival rate to over ...with non-squamous ...
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PAK1 kinase promotes cell motility and invasiveness through CRK-II serine phosphorylation in non-small cell lung cancer cells.
... inhibiting cell migration and promoting apoptosis in normal and malignant cells ...in cell motility and metastasis ...and cell motility and it seems that PAK kinases play a role in metastatic ...
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SINGLE AGENT DOCETAXEL AS SECOND- LINE CHEMOTHERAPY FOR PRETREATED PATIENTS WITH RECURRENT NON- SMALL CELL LUNG CANCER
... From January 2005 to May 2008 thirty six patients entered the study, including 28 men and 8 women. Some clinical characteristics of these patients are shown in table 1. The median patient’s age was 59 (range 39-71). The ...
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The prognostic value of phosphorylated AKT expression in non-small cell lung cancer: a meta-analysis.
... Moreover, the prognostic significance of p-AKT expression has been examined in many cancers, although evidence is still limited. Ermoian et al. [6] found no association between p-AKT and patient survival in gliomas; but ...
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Intercellular contact-dependent survival of human A549, NCI-H596 and NCI-H520 non-small cell lung carcinoma cell lines
... contact-regulated cell death of LIM 1863 colon carcinoma cells. In our cell lines, p53 status was previously studied and both A549 and H596 cells displayed wild-type p53 with mRNA and protein levels ...
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Synergistic Effects between mTOR Complex 1/2 and Glycolysis Inhibitors in Non-Small-Cell Lung Carcinoma Cells.
... Although the Warburg effect is a well-recognized hallmark of cancer metabolism, its regula- tory mechanism is still largely unclear. The mammalian target of rapamycin (mTOR) is a well conserved serine/threonine kinase, ...
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Association of TERT Polymorphisms with Clinical Outcome of Non-Small Cell Lung Cancer Patients.
... [1]. Non-small cell lung cancer (NSCLC) accounts for about 85% of lung cancer cases, with the majority of pa- tients presenting with advanced disease (stage IIIor IV), making surgical treatment ...
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Percutaneous cryoablation for the treatment of medically inoperable stage I non-small cell lung cancer.
... Surgical resection is currently the standard treatment for stage I non-small cell lung cancer (NSCLC). However, in patients who are medically inoperable due to significant comorbidities, other ...
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Non-Small Cell Lung Cancer: Screening, Diagnosis, and Staging
... The National Lung Cancer Screening Trial (NLST), 18 a large prospective randomized trial funded by the National Cancer Institute (NCI), to determine whether screening with low-dose CT, as compared with chest radiography ...
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Giant basal cell carcinoma
... The characteristics of this tumor define it as a Giant exophytic basal cell carcinoma. The patient was subjected to total surgical removal of the tumor. The histological examination showed changes in the ...
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