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Protein interactions

Predicting and validating protein interactions using network structure.

Predicting and validating protein interactions using network structure.

... other protein pairs containing this domain pair might also ...observed protein interaction network, the probabilities of domain-domain interactions are ...that protein interactions ...

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A flow cytometry-based FRET assay to identify and analyse protein-protein interactions in living cells.

A flow cytometry-based FRET assay to identify and analyse protein-protein interactions in living cells.

... detect protein interactions in living cells by combining FRET and flow ...physical interactions that can be detected in any cellular compartment ...

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Protein-protein interactions in clathrin vesicular assembly: radial distribution of evolutionary constraints in interfaces.

Protein-protein interactions in clathrin vesicular assembly: radial distribution of evolutionary constraints in interfaces.

... adaptor protein, across eukaryotes, despite the differences in the nature of ...their protein-protein interactions through the tandem repeat ...

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Predicting Protein-Protein Interactions Using BiGGER: Case Studies

Predicting Protein-Protein Interactions Using BiGGER: Case Studies

... of protein interactions and protein ...Traditionally, protein interactions have been elucidated by experimental methods or, with lower impact, by simulation with protein docking ...

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Cooperative DNA Recognition Modulated by an Interplay between Protein-Protein Interactions and DNA-Mediated Allostery.

Cooperative DNA Recognition Modulated by an Interplay between Protein-Protein Interactions and DNA-Mediated Allostery.

... their protein-protein interactions can evoke latent DNA specificities, causing them to occupy binding sites rarely bound by the isolated protein ...

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Protein-protein interactions as a strategy towards protein-specific drug design: the example of ataxin-1.

Protein-protein interactions as a strategy towards protein-specific drug design: the example of ataxin-1.

... in protein-protein interactions with other partners ...the protein, which has been proposed to play a ‘dual’ role in regulation of transcription and RNA-processing and/or metabo- lism ...

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Protein-protein interactions within late pre-40S ribosomes.

Protein-protein interactions within late pre-40S ribosomes.

... the protein-protein interactions between the seven non-ribosomal proteins bound to pre-43S ribosomes using recombinant proteins in in vitro binding ...the interactions between these factors ...

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The Development of a Universal In Silico Predictor of Protein-Protein Interactions

The Development of a Universal In Silico Predictor of Protein-Protein Interactions

... Protein-protein interactions (PPIs) are essential for understanding the function of biological systems and have been characterized using a vast array of experimental ...of ...

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Identification of an FHL1 protein complex containing gamma-actin and non-muscle myosin IIB by analysis of protein-protein interactions.

Identification of an FHL1 protein complex containing gamma-actin and non-muscle myosin IIB by analysis of protein-protein interactions.

... modular protein binding interface to mediate protein-protein ...the interactions of FHL1 could provide important new insights into its functional role in both skeletal muscle development and ...

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A Library of Plasmodium vivax Recombinant Merozoite Proteins Reveals New Vaccine Candidates and Protein-Protein Interactions.

A Library of Plasmodium vivax Recombinant Merozoite Proteins Reveals New Vaccine Candidates and Protein-Protein Interactions.

... novel protein-protein interactions, confirming that the proteins are functional and further supporting their potential as vaccine ...recombinant protein library will facilitate future studies ...

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A simple detection method for low-affinity membrane protein interactions by baculoviral display.

A simple detection method for low-affinity membrane protein interactions by baculoviral display.

... In summary, we have developed a new method for detecting membrane protein interactions using the BV display system. The BV display system reported here is expected to be highly useful for the analysis of ...

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Intragenic suppressor of Osiaa23 revealed a conserved tryptophan residue crucial for protein-protein interactions.

Intragenic suppressor of Osiaa23 revealed a conserved tryptophan residue crucial for protein-protein interactions.

... the protein-protein interactions between Osiaa23 and ...(C-D) Interactions between Osiaa23 and OsARFs, Osiaa23 and OsARF(WS)s in the yeast two-hybrid ...the protein-protein ...

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Interface-resolved network of protein-protein interactions.

Interface-resolved network of protein-protein interactions.

... combined with homology modeling [5], genomic data [19], and docking algorithms [20–22], to both assign and infer [23] binding interfaces. While it would be possible to construct an IIN from the residue level details ...

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Heparan sulfate proteoglycans: structure, protein interactions and cell signaling

Heparan sulfate proteoglycans: structure, protein interactions and cell signaling

... to protein interactions leading to cell ...the interactions of heparan sulfates and target proteins, regarding both the fine structure of the polysaccharide chain as well precise protein ...

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Wiki-pi: a web-server of annotated human protein-protein interactions to aid in discovery of protein function.

Wiki-pi: a web-server of annotated human protein-protein interactions to aid in discovery of protein function.

... Protein-protein interactions (PPIs) are the basis of biological ...the interactions of a protein can help understand its molecular function and its association with different biological ...

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Targeting protein-protein interactions for parasite control.

Targeting protein-protein interactions for parasite control.

... via interactions with other proteins, so protein-protein interactions (PPIs) offer a realm of unexplored potential drug targets and are thought to be the next-generation of drug ...few ...

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Diversity of T cell epitopes in Plasmodium falciparum circumsporozoite protein likely due to protein-protein interactions.

Diversity of T cell epitopes in Plasmodium falciparum circumsporozoite protein likely due to protein-protein interactions.

... a protein can be due to a lack of evolutionary constraint and/or selective pressures leading to ...immune interactions) a protein will evolve towards a more stable confirmation one might expect an ...

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The many faces of protein-protein interactions: A compendium of interface geometry.

The many faces of protein-protein interactions: A compendium of interface geometry.

... Only a small fraction of family pairs appeared both in fused and separate forms in PQS (Table 4). In screening non- genuine fusions, we also filtered out PQS entries containing both intra- and inter-type interfaces of a ...

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Predicting Pharmacodynamic Drug-Drug Interactions through Signaling Propagation Interference on Protein-Protein Interaction Networks.

Predicting Pharmacodynamic Drug-Drug Interactions through Signaling Propagation Interference on Protein-Protein Interaction Networks.

... Recently, the paradigm in drug discovery has shifted from single-target drugs to multi-target drugs [36]. Therefore, it becomes necessary to identify the performance of PD DDIs for multi- target drugs. To evaluate the ...

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Sequence motifs in MADS transcription factors responsible for specificity and diversification of protein-protein interaction.

Sequence motifs in MADS transcription factors responsible for specificity and diversification of protein-protein interaction.

... molecular interactions, which in turn determine biological functions of ...how protein sequences define interaction specificity is largely missing, in particular for paralogous protein families with ...

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