Severe malaria
Lack of association of interferon regulatory factor 1 with severe malaria in affected child-parental trio studies across three African populations.
... developing severe malaria, we performed a family-based test of association for 18 Single Nucleotide Polymorphisms (SNPs) across the gene in three African populations, using genotype data from 961 trios ...
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Recognition, perceptions and treatment practices for severe malaria in rural Tanzania: implications for accessing rectal artesunate as a pre-referral.
... With the aim of facilitating the successful introduction of rectal artesunate through a well-grounded understanding of symptom recognition and treatment practices for ‘‘severe malaria,’’ the study collected ...
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The role of animal models for research on severe malaria.
... on severe malaria have focused on infection by the malaria parasite Plasmodium ...with severe malaria show signs of profound metabolic derangement and cerebral ma- laria, and may have ...
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ASSOCIATION OF HBsAG WITH SEVERE MALARIA - FACT OR FICTION?
... AGAINST SEVERE MALARIA?: If this association is true, then people with HBV vaccination should be at a lesser risk of contracting malaria and its severity later ...against malaria are at ...
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Key words: severe malaria, Plasmodium falciparum, PfEMP1, pathogenesis, cytoadherence, rosetting,
... including severe malaria. Severe Malaria and PfEMP1 Genotype Few studies have reported associations of severe malaria and particular PfEMP1 protein ...19 severe ...
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Incidence of Severe Malaria Syndromes and Status of Immune Responses among Khat Chewer Malaria Patients in Ethiopia.
... Severe malaria symptoms independently associated with khat chewing Based on logistic regression tests, variables that are associated with khat chewing were age, body temperature, prostration, parasite load, ...
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Assessing the association of severe malaria infection and ABO blood groups in northwestern Ethiopia
... A cross-sectional study was conducted at Felegeselam Health Center, northwestren Ethiopia, to assess the asso- ciation of ABO blood group antigens with severe malaria in December 2011. Felegeselam is ...
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Volume status in severe malaria: no evidence provided for the degree of filling of the intravascular compartment.
... with severe malaria complicated by metabolic acidosis ...with severe acidosis (base defi cit ...with severe malaria can be satisfactorily resolved only through prospective randomized ...
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Mortality patterns and site heterogeneity of severe malaria in African children.
... of severe malaria have different predictablity for mortality at different ...of severe disease are different between sites reflecting disparate patient and parasite populations as well as different ...
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Severe malaria and Plasmodium
... impetus for the development of an anti-PAM vaccine. However, several issues concern- ing the expression of antigens by PAM para- sites and the precise immunological mechan- isms involved in protection remain unre- solved ...
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Diagnosing severe falciparum malaria in parasitaemic African children: a prospective evaluation of plasma PfHRP2 measurement.
... ‘‘true’’ severe malaria with increasing sequestered parasite ...causing severe disease independent of a high total parasite ...‘‘true’’ severe malaria was derived according to PfHRP2 ...
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Rev. Soc. Bras. Med. Trop. vol.50 número2
... in severe malaria" highlights the importance of the SNPs in TLR4 (Asp299Gly) and TLR9 (-1237C/T and -1486C/T) in ...of malaria and the association with severe clinical manifestations of ...
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Vascular dysfunction as a target for adjuvant therapy in cerebral malaria
... addition, severe malaria patients show lower reactive hyperaemia-peripheral arterial tonometry (RH- PAT) index (a measurement of reactive vasodilation) than uninfected controls or patients with ...
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Dihydrofolate-Reductase Mutations in Plasmodium knowlesi Appear Unrelated to Selective Drug Pressure from Putative Human-To-Human Transmission in Sabah, Malaysia.
... nation malaria setting in Sabah where hospital admission is mandatory for all malaria cases, fever was frequently treated empirically with single dose SP by public health officials in the community for ...
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Hemolysis is associated with low reticulocyte production index and predicts blood transfusion in severe malarial anemia.
... The study was designed as a case-control study to identify variables that discriminate malaria patients with and without SMA. Variables associated with RBC production, RBC removal, clinical and parasitological ...
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Rev. bras. ter. intensiva vol.23 número3 en v23n3a15
... Severe P. falciparum parasitemia, defined as the infection of more than 5% of the red blood cells, has been correlated with an increase in microcirculatory effects and with harmful metabolic effects, such as ...
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Rev. Soc. Bras. Med. Trop. vol.47 número1
... Introduction: We evaluated the in vitro antimalarial activity of tigecycline as an alternative drug for the treatment of severe malaria. Methods: A chloroquine-sensitive Plasmodium falciparum reference ...
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Defining childhood severe falciparum malaria for intervention studies.
... the malaria slide performed after admission is the first malaria investigation of their ...of malaria, the MAFs would be increased among malnutrition ...of severe malaria in whom the MAF ...
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Knowledge, attitudes and practices about malaria in an urban community in south-western Nigeria
... Malaria control depends heavily on prompt, effec- tive treatment and not knowing the correct dose may be a barrier to effective case management. Given these results, in an urban setting, public health inter- ...
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CD19.R17: Malaria eradication
... the malaria eradication programs and to urge them to continue to take the necessary steps to ensure that these programs are properly financed and efficiently administered and that the most effective methods are ...
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