Squamous cell of head and neck
Genetic alterations in head and neck squamous cell carcinomas
... loss of nor- mal function of the TP53 tumor suppressor gene is believed to contribute to the develop- ment of the majority of human cancers ...17p13.1 and consists of 11 exons ...
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A novel role for BDNF-TrkB in the regulation of chemotherapy resistance in head and neck squamous cell carcinoma.
... MAPK, and Src signaling pathways to induce various physiological functions including anti-apoptosis and cell proliferation, angiogenesis, anoikis and metastasis ...results of current ...
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GSTM1, GSTT1 and GSTP1 Ile105Val polymorphisms in outcomes of head and neck squamous cell carcinoma patients treated with cisplatin chemoradiation
... 90% of CDDP excretion in our patients was measured within the first 24 h after ...kinetics of CDDP ...29 and considered essential to pharmacokinetics and pharmacodynamics stud- ies 30 ...urine ...
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Expression of the T cell receptor αβ on a CD123+ BDCA2+ HLA-DR+ subpopulation in head and neck squamous cell carcinoma.
... regulation of the TCR subsequent to cell ...control. Cell viability was confirmed by staining with Annexin and ...shown) and BDCA2 and was located in the centre of the PDC ...
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Regional Neck Metastization of Head and Neck Skin Cancer
... in head and neck, due to chronic sun exposure. The risk of neck metastasis depends on their histology and ...Melanoma and Merkel carcinoma with N0 neck stage, have ...
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Evaluation of Tissue Expression and Salivary Levels of HER2/neu in Patients with Head and Neck Squamous cell Carcinoma
... expression and age, gender, tumor size, lymph node and distant metastasis, tumoral stage and histologic differentiation in our ...over-expression and overall survival of patients with ...
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Invasive head and neck cutaneous squamous cell carcinoma: clinical and histopathological characteristics, frequency of local recurrence and metastasis
... cavity, and internal organs (lungs), where the incidence of metastases is ...findings of other studies where the frequency of metastatic cuta- neous SCC in regional lymph nodes is low, ...
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Evidence-Based Treatment Options in Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck
... development of the past decade in the first-line treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) was the ...
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Epidermal growth factor receptor inhibition reduces angiogenesis via hypoxia-inducible factor-1α and Notch1 in head neck squamous cell carcinoma.
... The squamous epithelial tissue specific and time inducible combined Tgfbr1/Pten knockout mice (Tgfbr1/Pten 2cKO, K14-Cre ERtam ; Tgfbr1 flox/flox ; Pten flox/flox ) were maintained as previous- ly described ...
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Impact of HPV infection on the development of head and neck cancer
... cancer of the hypophar- ynx, nasopharynx, oropharynx, and ...for head and neck cancer in France in 2007, and tumors were more frequently detected in the oropharynx among these ...
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Pilomatrixoma in the head and neck
... plates of necrotic squamous cells amidst neutrophils, lymphocytes and multinucleated giant cells with fibrosis, suggesting ...sibility of a well differentiated squamous cell ...
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Indication of elective contralateral neck dissection in squamous cell carcinoma of the hypopharynx
... files of hypopharyngeal squamous cell carcino- ma patients undergoing neck dissection were ...description of the lymph nodes involved were excluded from the ...consisted of 174 ...
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Cetuximab plus platinum-based chemotherapy in head and neck Squamous Cell Carcinoma: a retrospective study in a single Comprehensive European Cancer Institution
... patients) and included approx- imately half of the total number of patients involved in the EXTREME ...outside of a clinical ...months) and OS (11 ...population, and a Figure 1. ...
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Dose dependent activation of retinoic acid-inducible gene-I promotes both proliferation and apoptosis signals in human head and neck squamous cell carcinoma.
... survival of a virus relies upon the evolution of strategies that modulate host cell signaling pathways, particularly those governing apoptosis and cell survival ...completion of ...
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Analysis of death receptor 5 and caspase-8 expression in primary and metastatic head and neck squamous cell carcinoma and their prognostic impact.
... expression of DR5. In fact, one study has shown that TRAIL enhances the invasion of apoptosis-resistant pancreatic ductal adenocarcinoma cells in vitro and increases distant metastasis ...liver) ...
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Expression of DNA translesion synthesis polymerase η in head and neck squamous cell cancer predicts resistance to gemcitabine and cisplatin-based chemotherapy.
... Materials and Methods. To test the specificity of the developed antibody, we used this antibody to probe the presence of Pol using cell lysates from the human fibroblast GM637 cells or the ...
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Classical and molecular cytogenetic analysis in head and neck squamous cell carcinomas
... tion and cytogenetic analysis were carried out by standard techniques on primary cultures, as previously described (Rogatto et ...(Sigma), and the cells were grown in Ham’s F-10 medium (Sigma) supplemented ...
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Incidence of Etiologic Factors in Squamous Cell Carcinoma of Head and Neck in Ahvaz
... descriptive, and prospective research, from September 2006 to December 2010, patients in the ELT and surgical wards of the Imam Khomeini and Golestan hospitals (the major university hospitals ...
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Effect of ethanol extracts of Antrodia cinnamomea on head and neck squamous cell carcinoma cell line
... Head and neck squamous cell carcinoma (HNSCC) is one of the most common malignant tumors, representing over 95% of all head and neck cancer cases ...
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Mutational landscape of head and neck squamous cell carcinomas in a South Asian population
... Receptor) and ERBB4 (Erb-B2 Receptor Tyrosine Kinase 4) were identified as ...addition, cell cycle, actin cytoskeleton regulation, PI3K-Akt signal- ing and other pathways in cancer were among those ...
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