Telomere length
Telomere length as a biomarker for adiposity changes after a multidisciplinary intervention in overweight/obese adolescents: the EVASYON study.
... A calibration curve of the same DNA sample of reference (64– 0.25 ng in 2-fold dilutions) was included for each measurement as a standard, to control the day-to-day variations. Standard curve with linearity R 2 .0.98 was ...
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Telomere length in subjects with schizophrenia, their unaffected siblings and healthy controls : evidence of accelerated aging
... Sayer, A.A., Barbieri, M., Bekaert, S., Bischoff, C., Brooks-Wilson, A., Chen, W., Cooper, C., Christensen, K., De Meyer, T., Deary, I., Der, G., Diez Roux, A., Fitzpatrick, A., Hajat, A., Halaschek-Wiener, J., Harris, ...
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Telomere Length in Peripheral Blood Leukocytes Is Associated with Severity of Biliary Atresia.
... ated telomere length in BA patients, but did not measure the activity of telomerase ...of telomere length relating to BA in these ...between telomere shortening and the severity of ...
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Correlation of chromosomal instability, telomere length and telomere maintenance in microsatellite stable rectal cancer: a molecular subclass of rectal cancer.
... Shortened telomeres have been linked to chromosomal instability (CIN) in the setting of age-related diseases associated with genetic disruption and carcinogenesis [5]. Telomeres are comprised of repeat TTAGGG sequences ...
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Telomere length of circulating leukocyte subpopulations and buccal cells in patients with ischemic heart failure and their offspring.
... A secondary focus of our study was the heredity of TL traits among cell populations. Heritability of mean leukocyte telomere length has been demonstrated previously [12,14,24]. We now add to this the ...
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Systemic lupus erythematosus and vitamin D deficiency are associated with shorter telomere length among African Americans: a case-control study.
... or telomere length at baseline in SLE patients, there was a significant correlation between telomere length and 25(OH)D level in all subjects (controls and patients) with the lowest 25(OH)D ...
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Sedentary behavior, physical activity and cardiorespiratory fitness on leukocyte telomere length
... influence telomere length (as was the purpose of this study) could provide important insights that assist in identifying factors that may help to attenuate risks associated with these ...
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Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings.
... that telomere length is reduced in hippocampal CA1 neurons in Alzheimer’s disease, and this has been postulated to result, at least in part, from oxidative stress ...whether telomere length ...
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Extreme telomere length dimorphism in the Tasmanian devil and related marsupials suggests parental control of telomere length.
... distinct telomere size classes is of great ...of telomere length control in mammals [47]. There are two telomere shortening mechanisms, namely the gradual telomere attrition which ...
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Decreased leukocyte telomere length (LTL) is associated with stroke but unlikely to be causative.
... The telomere length of stroke subjects was significantly shorter than that of siblings and normal ...of telomere length between the sibling and normal ...the telomere shortening in ...
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Preanalytical Conditions and DNA Isolation Methods Affect Telomere Length Quantification in Whole Blood.
... quantifying telomere length originally published by Cawthon [22, 31] and have established a cost- and time-effective multiplex assay, which can be run in the 384-well format using as little as 10 ng of DNA ...
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Blood cell telomere length is a dynamic feature.
... to telomere length they were ...in telomere length (‘‘RTL decreasers’’) whereas 25 demonstrated elongated/stable telomeres (‘‘RTL ...between telomere length and body mass index ...
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Telomere length modulation in human astroglial brain tumors.
... in telomere length [48] and it has been reported that the forced tethering of a large number of TRF1 molecules to a single telomere induce a significant shortening of telomere ...progressive ...
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Depressive symptoms are not associated with leukocyte telomere length: findings from the Nova Scotia Health Survey (NSHS95), a population-based study.
... leukocyte telomere length may reflect the fact that leukocyte telomere length is influenced by cumulative environ- mental factors over time, whereas assessments of depressive symptoms ...
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Telomere length trajectory and its determinants in persons with coronary artery disease: longitudinal findings from the heart and soul study.
... of telomere shortening, cells lose the ability to replicate and may cease dividing (senescence) or undergo programmed cell ...Human telomere length is influenced by both genetic and environmental ...
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Leukocyte telomere length in HIV-infected and HIV-exposed uninfected children: shorter telomeres with uncontrolled HIV viremia.
... shortening telomere length and potentially mimicking immunosenescence ...addition, telomere dynamics in HIV infection are complicated by the fact that telomerase comprises a reverse transcriptase ...
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Telomere length and childhood trauma in Colombians with depressive symptoms
... Epidemiological studies have provided strong evidence for the finding that adverse experiences during childhood, such as neglect or abuse, are associated with signifi- cant increases in the risk of developing depression. ...
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Longer leukocyte telomere length is associated with smaller hippocampal volume among non-demented APOE ε3/ε3 subjects.
... to telomere shortening due to the end-replication ...critical length is reached, the cell will either undergo apoptosis or enter a state of replicative senescence ...that telomere length (TL) ...
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Healthy lifestyle and leukocyte telomere length in U.S. women.
... PCR-based telomere assay developed by Cawthon et al ...of telomere repeat copy number to single-copy gene copy number (T:S ratio) was derived and the relative LTL was measured as the exponentiated T:S ...
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Telomere Length – a New Biomarker in Medicine
... Ponadto dostęp- ność sekwencji telomerowych dla telomerazy jest regulo- wana przez białka TRF1 i TRF2 (TRF1 – reguluje dostęp telomerazy, nadekspresja TRF2 powoduje skracanie się [r] ...
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