Therapeutic efficacy
Preventive and therapeutic efficacy of finasteride and dutasteride in TRAMP mice.
... Method/Principal Findings: Six-week-old C57BL/6 TRAMP x FVB male mice were randomized to AIN93G control or pre- and post- finasteride and dutasteride diet (83.3 mg drug/kg diet) groups (n =30–33) that began at 6 and 12 ...
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Application of Fluorescent Protein Expressing Strains to Evaluation of Anti-Tuberculosis Therapeutic Efficacy In Vitro and In Vivo.
... anti-TB efficacy of rifampicin and isoniazid therapy in vitro and in vivo using the L5-tdTomato strain demonstrated that this strain can be used to identify anti-TB therapeutic efficacy as quickly as ...
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Fabrication principles and their contribution to the superior in vivo therapeutic efficacy of nano-liposomes remote loaded with glucocorticoids.
... We report here the design, development and performance of a novel formulation of liposome- encapsulated glucocorticoids (GCs). A highly efficient (.90%) and stable GC encapsulation was obtained based on a transmembrane ...
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Therapeutic efficacy of florfenicol against Streptoccoccus agalactiae infection in nile tilápia (Oreochromis nicoticus)
... After the safety assay, the therapeutic efficacy of FLO was tested. The florfenicol in doses from 10 to 60 mg/Kg of live weight was shown to be ineffective to control S. agalactiae infection in Nile ...
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Radiotherapy-induced anti-tumor immunity contributes to the therapeutic efficacy of irradiation and can be augmented by CTLA-4 blockade in a mouse model.
... The molecular mechanisms that mediate anti-tumor immunity, in terms of irradiation-induced immunogenic tumor cell death and its impact on the prognosis of cancer patients, have also been investigated. Apetoh et al. ...
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Factors Associated with Therapeutic Efficacy of Intravesical OnabotulinumtoxinA Injection for Overactive Bladder Syndrome.
... Overall, 89 patients received intravesical injection. Eighty patients, including 42 men and 38 women, had received follow-up at 3 months. The overall success rate was 63.8%. The global response assessment, urgency ...
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Preconditioning via angiotensin type 2 receptor activation improves therapeutic efficacy of bone marrow mononuclear cells for cardiac repair.
... Similar to the in vivo data, in vitro angiogenesis assay also showed that HUVEC tube length was significantly increased in the presence of conditioned medium collected from AT[r] ...
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EVALUATION OF THE ELISA-F29 TEST AS AN EARLY MARKER OF THERAPEUTIC EFFICACY IN ADULTS WITH CHRONIC CHAGAS DISEASE
... These studies demonstrate the effectiveness of the trypanocidal treatment after a period of 15 years. The required prolonged time of follow-up constitutes the main difficulty for the therapeutic evaluation in ...
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Administration of BMSCs with muscone in rats with gentamicin-induced AKI improves their therapeutic efficacy.
... showed therapeutic effect on the regulation of some inflammatory ...better therapeutic action on down-regulating RANTES and MIP-2 (Figure 7A), and the effect Figure ...
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EVALUATION OF THE THERAPEUTIC EFFICACY OF LEVAMISOLE HYDROCHLORIDE ON THIRD- STAGE LARVAE OF Lagochilascaris minor IN EXPERIMENTALLY INFECTED MICE
... Although therapeutic combinations with levamisole often present satisfactory results in human lagochilascariosis, it is important to consider the safety and efficacy of these combinations because these ...
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Therapeutic efficacy of neuromuscular electrical stimulation and electromyographic biofeedback on Alzheimer’s disease patients with dysphagia
... A series of 103 Alzheimer ’s disease patients with dysphagia were divided into 2 groups, among which the control group (n=50) received swallowing function training and the treatment grou[r] ...
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Protective and therapeutic efficacy of Mycobacterium smegmatis expressing HBHA-hIL12 fusion protein against Mycobacterium tuberculosis in mice.
... Tuberculosis (TB) remains a major worldwide health problem. The only vaccine against TB, Mycobacterium bovis Bacille Calmette-Guerin (BCG), has demonstrated relatively low efficacy and does not provide ...
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Preparation for radioiodine therapy: How to increase therapeutic efficacy and accelerate unbound radioiodine excretion
... Therapeutic application of radioiodine 131 I in postop- erative ablation of the remaining thyroid tissue, as well as in treatment of recidives and/or local and remote metastases of differentiated thyroid carcinoma ...
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Therapeutic efficacy by targeting correction of Notch1-induced aberrants in uveal tumors.
... the therapeutic effect of adenovirus through the joint application of traditional radiotherapy or chemotherapy have augmented responses, but toxicity remains a major limiting factor ...the efficacy of the ...
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The emergence of YMDD mutants precedes biochemical flare by 19 weeks in lamivudine-treated chronic hepatitis B patients: an opportunity for therapy reevaluation
... of therapeutic efficacy associated with the development of resistance to lamivudine (LMV) and the availability of new alterna- tive treatments for chronic hepatitis B patients, early detection of viral ...
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SA-4-1BBL costimulation inhibits conversion of conventional CD4+ T cells into CD4+ FoxP3+ T regulatory cells by production of IFN-γ.
... robust therapeutic efficacy against established TC-1 tumors ...peutic efficacy was associated with tumor-specific killing activity, high frequency of IFN-c secreting CD4 ...
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Rev. LatinoAm. Enfermagem vol.21 número6
... EN 1499 method, logarithmic reduction factors were determined for the number of colony forming units of Escherichia coli K12 before and after hand hygiene of 15 volunteer subjects, and compared using the one-tailed ...
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Experimental and placebo auriculotherapy for stressed nurses: randomized controlled trial
... the therapeutic efficacy of experimental and sham auricu- lotherapy for the treatment of stress levels identified in the nurses of a large Charity Hospital in São Paulo, comparing with a control group ...
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Therapeutic Assessment of Chloroquine-Primaquine Combined Regimen in Adult Cohort of Plasmodium vivax Malaria from Primary Care Centres in Southwestern India.
... Outstanding therapeutic efficacy as evidenced in this study and other parallel study [3] reassures the contin- uation of CQ-PQ combined regimen for the treatment of uncomplicated ...of therapeutic ...
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Enhanced antitumor efficacy and reduced systemic toxicity of sulfatide-containing nanoliposomal doxorubicin in a xenograft model of colorectal cancer.
... low therapeutic index of the anticancer drugs due to serious toxicity to normal ...improved therapeutic efficacy of SCL-DOX was obtained without an increase in toxicity to the heart or to the bone ...
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