[PDF] Top 20 Hippocampal network oscillations in APP/APLP2-deficient mice.
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Hippocampal network oscillations in APP/APLP2-deficient mice.
... prominent network patterns with highly synchronized neuronal behavior ...occurrence in normal animals is state-dependent and mutually exclusive, they do share a number of common mechanisms ...both ... See full document
7
APP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active Zone.
... changed in the elderly mice, when impairments in spatial and working memory become obvious ...the APP-KO mice, deletion of both APP and APLP2 provokes a lethal phenotype ... See full document
22
Network models predict that reduced excitatory fluctuations can give rise to hippocampal network hyper-excitability in MeCP2-null mice.
... MeCP2- deficient brain is the presence of hyper-excitable network ...responses. In the hippocampus, such responses exist despite there being an overall decrease in spontaneous excitatory drive ... See full document
11
In vitro dose-dependent inhibition of the intracellular spontaneous calcium oscillations in developing hippocampal neurons by ketamine.
... abnormalities in the frequency and amplitude of the cytosolic calcium oscillations can impact the normal physiological functions of neuronal ...developing hippocampal neurons as its study subjects to ... See full document
8
DBA/2J genetic background exacerbates spontaneous lethal seizures but lessens amyloid deposition in a mouse model of Alzheimer's disease.
... aid in the identification of new genes and pathways it is necessary to generate alternative mouse strains relevant to ...fruitful in the identification of genetic factors that modulate other disease ... See full document
18
A novel role for CD55 in granulocyte homeostasis and anti-bacterial host defense.
... CD55 in granulocyte homeostasis and anti- bacterial host ...CD55-deficient mice display increased numbers of circulating ...granulocytes in the blood stream, the marginated pool, and the ... See full document
8
Functional deficiency of MHC class I enhances LTP and abolishes LTD in the nucleus accumbens of mice.
... expressed in various brain areas, especially in regions undergoing activity-dependent synaptic plasticity, but their role in the nucleus accumbens (NAc) is ...unknown. In this study, we ... See full document
8
Rev Bras Med Esporte vol.13 número5
... role in this context. In this review, we showed the re- sults of different models and configurations of physical exercise in oxidative and neurotrophic metabolism of the Central Nervous Sys- tem ... See full document
6
Differential and site specific impact of B cells in the protective immune response to Mycobacterium tuberculosis in the mouse.
... cells in the absence of immunoglobulin in the protective immune response to ...Mtb in the spleen but that excess IL-10 is directly responsible for the increased susceptibility seen in ... See full document
11
Partial absence of pleuropericardial membranes in Tbx18- and Wt1-deficient mice.
... newborn mice revealed additional, as yet undescribed, pericardial defects that prompted us to investigate the role of Tbx18 in the development of this tissue in more ...Tbx18-null mice die ... See full document
9
A Susceptible Mouse Model for Zika Virus Infection.
... placed in the Zika forest in Uganda in 1947; thereafter, ZIKV was isolated from a pool of Aedes africanus mosquitoes from the same forested area ...detected in several African and Asian ... See full document
13
Renal failure affects the enzymatic activities of the three first steps in hepatic heme biosynthesis in the acute intermittent porphyria mouse.
... this in vivo study using the AIP mouse ...weeks in order to maintain high hepatic production and high flow of both porphyrin precursors and porphyrin throughout the ...AIP mice developed a ... See full document
9
IL-15 deficient tax mice reveal a role for IL-1α in tumor immunity.
... fixed in 10% buffered formalin and paraffin-embedded sections were processed for immunohisto- chemical ...deparaffinized in xylene, and rehydrated in deionized ...pressure) in citric acid ... See full document
11
Characterization of Lethal Zika Virus Infection in AG129 Mice.
... DENV in wildtype mice, we postulate that ZIKV proteins likely cannot bind and degrade the homologs for STING [29,30] and STAT-2 [31]; therefore, ZIKV-infected wildtype mice induce efficient IFN-α/β ... See full document
11
Quantitative changes of nicotinic receptors in the hippocampus of dystrophin-deficient mice
... dystrophin in Duchenne muscle dystrophy (DMD) and in the mutant mdx mouse results in progressive muscle degeneration, structural changes at the neuromuscular junction, and destabilization of the ... See full document
9
The Vi capsular polysaccharide enables Salmonella enterica serovar typhi to evade microbe-guided neutrophil chemotaxis.
... from mice with C3-deficiency [39]. In serum from C3-deficient mice (bred on a C57BL/6 background), neutrophils from C3-deficient mice did not exhibit a chemotactic response ... See full document
9
Afadin regulates puncta adherentia junction formation and presynaptic differentiation in hippocampal neurons.
... lost in mossy fiber- CA3 pyramidal cell synapses in the afadin f/f ;camk2a-Cre hippo- campus in which the afadin gene was inactivated in excitatory neurons after synaptogenesis, and that the ... See full document
8
Survival of adult generated hippocampal neurons is altered in circadian arrhythmic mice.
... Bmal1 in cell proliferation is ...proliferation in the SGZ in Bmal1-KO animals, and attributed this to enhanced entry and diminished exit from the cell cycle ...with in vitro cell culture ... See full document
7
Cardiovascular changes in atherosclerotic ApoE-deficient mice exposed to Co60 (γ) radiation.
... mainly in terms of induction of cancer, somatic mutations in exposed individuals can also lead to other maladies, and heritable mutations are implicated in disease risk in future generations ... See full document
10
Altered lipid metabolism in residual white adipose tissues of Bscl2 deficient mice.
... linearity in response for specific lipids was observed, and to ensure that the ratios of specific lipid ion abundances compared to other lipids within the mixture remained constant ...operating in infusion ... See full document
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