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[PDF] Top 20 A Library of Plasmodium vivax Recombinant Merozoite Proteins Reveals New Vaccine Candidates and Protein-Protein Interactions.

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A Library of Plasmodium vivax Recombinant Merozoite Proteins Reveals New Vaccine Candidates and Protein-Protein Interactions.

A Library of Plasmodium vivax Recombinant Merozoite Proteins Reveals New Vaccine Candidates and Protein-Protein Interactions.

... lack of knowledge about the molecular mechanisms of merozoite inva- sion and antimalarial immunity, relatively few ...P. vivax antigens have been investigated as vac- cine ... See full document

24

TLR5-dependent immunogenicity of a recombinant fusion protein containing an immunodominant epitope of malarial circumsporozoite protein and the FliC flagellin of Salmonella Typhimurium

TLR5-dependent immunogenicity of a recombinant fusion protein containing an immunodominant epitope of malarial circumsporozoite protein and the FliC flagellin of Salmonella Typhimurium

... immunogenicity of new malaria vaccine candidates based on the expression of fusion proteins containing immunodominant epitopes of merozoites and Salmonella enterica ... See full document

5

Comparative recognition by human IgG antibodies of recombinant proteins representing three asexual erythrocytic stage vaccine candidates of Plasmodium vivax

Comparative recognition by human IgG antibodies of recombinant proteins representing three asexual erythrocytic stage vaccine candidates of Plasmodium vivax

... studies of the naturally acquired antibody responses to merozoite sur- face protein-1 (MSP-1) of Plasmodium vivax, we had evidence that the responses to distinct erythrocytic ... See full document

6

Expression and Evaluation of Recombinant Plasmodium knowlesi Merozoite Surface Protein-3 (MSP-3) for Detection of Human Malaria.

Expression and Evaluation of Recombinant Plasmodium knowlesi Merozoite Surface Protein-3 (MSP-3) for Detection of Human Malaria.

... markers and vaccine candidates for ...variety of antigens; one of which is the merozoite surface protein (MSP)-3 which has partially significant effects on retarding ... See full document

15

Antigenicity and Immunogenicity of Plasmodium vivax Merozoite Surface Protein-3

Antigenicity and Immunogenicity of Plasmodium vivax Merozoite Surface Protein-3

... comparison of human antibody reactivities to different antigens revealed major ...FP-2 and FP-3 of PvMSP-3b, possibly because they share a number of common B and T cell ...lack ... See full document

10

A viral-human interactome based on structural motif-domain interactions captures the human infectome.

A viral-human interactome based on structural motif-domain interactions captures the human infectome.

... analysis of the true positive results found by the three methods did not show significant differences when the VirHostNet and NIAID databases were used (one-tailed exact Fisher test; P-value ...predictions ... See full document

13

Francisca Monteiro PhD thesis

Francisca Monteiro PhD thesis

... levels of lactate, ammonia and alanine, a behavior that, with the exception of alanine, is not shown by Sf9 cells, at least in such an ...overexpression of PC did not succeed in diminishing ... See full document

228

R Alan Wilson+ , Rachel S Curwen, Simon Braschi, Stephanie L Hall, Patricia S Coulson, Peter D Ashton

R Alan Wilson+ , Rachel S Curwen, Simon Braschi, Stephanie L Hall, Patricia S Coulson, Peter D Ashton

... moieties of glycoproteins and glycolipids that can func- tion as antigenic epitopes, provoking antibody produc- ...component of protection (Eberl et al. 2001). This is especially true of the ... See full document

6

Sequence motifs in MADS transcription factors responsible for specificity and diversification of protein-protein interaction.

Sequence motifs in MADS transcription factors responsible for specificity and diversification of protein-protein interaction.

... structures and contain information about specific molecular interactions, which in turn determine biological functions of ...how protein sequences define interaction specificity is largely ... See full document

13

Dynamic proteomics of human protein level and localization across the cell cycle.

Dynamic proteomics of human protein level and localization across the cell cycle.

... Regulation of proteins across the cell cycle is a basic process in cell ...lack of methods to accurately follow protein levels and localizations over ...percent of human genes ... See full document

11

Interface-resolved network of protein-protein interactions.

Interface-resolved network of protein-protein interactions.

... specificity and competition between protein-protein interactions ...This new type of network represents interactions between individual interfaces used in functional ... See full document

14

BM5 - SEQUENCE DIVERSITY, ANTIBODY RECOGNITION AND EVOLUTION OF THE MALARIA VACCINE CANDIDATE ANTIGEN MEROZOITE SURFACE PROTEIN-2 (MSP-2) OF PLASMODIUM FALCIPARUM

BM5 - SEQUENCE DIVERSITY, ANTIBODY RECOGNITION AND EVOLUTION OF THE MALARIA VACCINE CANDIDATE ANTIGEN MEROZOITE SURFACE PROTEIN-2 (MSP-2) OF PLASMODIUM FALCIPARUM

... non-normalized and normalized cDNA libraries of CL Brener epimastigotes (Urmenyi et ...1999) and were kindly provided by ...BLASTN and BLASTX programs indicates that 75% of the ESTs ... See full document

43

Immunogenicity of a Prime-Boost Vaccine Containing the Circumsporozoite Proteins of Plasmodium vivax in Rodents

Immunogenicity of a Prime-Boost Vaccine Containing the Circumsporozoite Proteins of Plasmodium vivax in Rodents

... transmission of this disease would benefit from the development of an efficacious ...case of the deadly parasite P. falciparum, the recombinant RTS,S vaccine containing the ... See full document

15

Characterization of a new malaria vaccine candidate against Plasmodium vivax using genetically modified rodent Plasmodium parasites

Characterization of a new malaria vaccine candidate against Plasmodium vivax using genetically modified rodent Plasmodium parasites

... knowledge of the Plasmodium genome and the possibility of its manipulation, it was demonstrated that sporozoites lacking certain stage-specific genes become impaired to complete their ... See full document

68

Cellular immune response of humans to the circumsporozoite protein of Plasmodium vivax

Cellular immune response of humans to the circumsporozoite protein of Plasmodium vivax

... [r] ... See full document

6

Targeting protein-protein interactions for parasite control.

Targeting protein-protein interactions for parasite control.

... formaldehyde and embedded in paraffin using standard histological ...deparaffinized and partially digested using pepsin HCl (DakoCytomation, Hamburg, Germany) for approximately 7 minutes and hybrid- ... See full document

12

Expressão, purificação e caracterização da proteína capsidial de Cowpea mild mottle virus e suas aplicações na detecção viral

Expressão, purificação e caracterização da proteína capsidial de Cowpea mild mottle virus e suas aplicações na detecção viral

... antigenicity of CpMMV-CP was assessed using the software ANTHEPROT (Deleage et ...(1986) and Welling et al. (1985). The pattern of antigenicity in the two methods used presented some differences in ... See full document

56

Deletion of a malaria invasion gene reduces death and anemia, in model hosts.

Deletion of a malaria invasion gene reduces death and anemia, in model hosts.

... older and that there were small differences in the absolute number injected parasites or the reticulocytes on Day ...deletion of msp7 gene does not have a major effect on acute infection in 6– 8 week old ... See full document

8

Associação de metemoglobinemia e deficiência de glicose-6-fosfato desidrogenase em pacientes com malária tratados com primaquina.

Associação de metemoglobinemia e deficiência de glicose-6-fosfato desidrogenase em pacientes com malária tratados com primaquina.

... malária vivax ou mista V+F (vivax + falciparum) e da unidade hospitalar ...malária vivax e 1 com malária mista; Grupo 2: 161 indivíduos sem diagnóstico clínico de metemoglobinemia, em tratamento com ... See full document

4

Plasmodium vivax antigen discovery based on alpha-helical coiled coil protein motif.

Plasmodium vivax antigen discovery based on alpha-helical coiled coil protein motif.

... titers and antibody ...P. vivax parasites; these four peptides induced the strongest antibody ...PvPep43 and PvPep82.02 are chromosome- associated proteins with the other two being ... See full document

13

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