[PDF] Top 20 Molecular basis of live-attenuated influenza virus.
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Molecular basis of live-attenuated influenza virus.
... Human influenza is a seasonal disease associated with significant morbidity and ...inactivated influenza virus strains mixture, or by intranasal administration of a group of three ... See full document
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Influenza H5 hemagglutinin DNA primes the antibody response elicited by the live attenuated influenza A/Vietnam/1203/2004 vaccine in ferrets.
... component of strategies aiming to prevent and control pandemic ...route of natural infection, live attenuated influenza virus (LAIV) vaccines induce both local mucosal and ... See full document
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Immunogenicity and protective efficacy of a live attenuated H5N1 vaccine in nonhuman primates.
... spread of highly pathogenic H5N1 influenza viruses among poultry and wild birds, together with the emergence of drug-resistant variants and the possibility of human-to-human transmission, has ... See full document
11
Molecular basis of efficient replication and pathogenicity of H9N2 avian influenza viruses in mice.
... avian influenza viruses (AIVs) have shown expanded host range and can infect mammals, such as humans and ...mechanisms of mammalian adaptation and interspecies transmission of H9N2 AIVs remain poorly ... See full document
9
The Yellow Fever 17D Vaccine Virus as a Vector for the Expression of Foreign Proteins: Development of New Live Flavivirus Vaccines
... site of the vi- ral genome. The pioneer study of Racaniello and Baltimore (1981) first showed the feasibility to generate poliovirus from cloned ...development of in vitro transcription systems it ... See full document
9
Potent host-directed small-molecule inhibitors of myxovirus RNA-dependent RNA-polymerases.
... regulators of the activity of RdRp complexes of different negative-strand RNA viruses [64]: host cell kinases of the PI3K- Akt pathway manipulate paramyxovirus RdRp activity through ... See full document
14
Comparative sequence analysis of the P-, M- and L-coding region of the measles virus CAM-70 live attenuated vaccine strain
... intention of the present study was to acquire genetic information about the vaccine produced at our ...role of these proteins in the attenuation process. The study of molecular characteristics ... See full document
10
Pathogenesis of the 1918 pandemic influenza virus.
... first influenza pandemic of the 21st century was caused by a novel swine-origin H1N1 influenza virus that emerged in early ...This virus is substantially less virulent than the 1918 ... See full document
4
Intranasal immunization of baculovirus displayed hemagglutinin confers complete protection against mouse adapted highly pathogenic H7N7 reassortant influenza virus.
... units of adjuvant free, purified live Bac- HA, inactivated Bac-HA, inactivated H7N7 reassortant virus (IV), or wild-type baculovirus (Bac-wt; 10 8 PFU) and PBS ...with live Bac-HA, inactivated ... See full document
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Generation and Characterization of Live Attenuated Influenza A(H7N9) Candidate Vaccine Virus Based on Russian Donor of Attenuation.
... Generation of A(H7N9) candidate vaccine viruses by reverse genetics The mutations present in the HA of a vaccine candidate seed virus could potentially affect its antigenicity and effectiveness [39, ... See full document
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Rapid strategy for screening by pyrosequencing of influenza virus reassortants--candidates for live attenuated vaccines.
... number of methods which have been used for reassortment detection, including real-time RT- PCR [50], conventional RT-PCR [25,26], and conventional sequencing ...genotyping of influenza reassortants ... See full document
11
Análise retrospectiva de aspectos clínicoepidemiológicos de infecções respiratórias agudas virais em crianças atendidas em um serviço de emergência de um hospital terciário de Fortaleza
... crianças por pneumonia correspondem a mais de 960 mil casos por ano (ALMEIDA; FERREIRA FILHO, 2004). Deve ser ressaltado que ainda existe uma escassez de dados referentes a pneumonia em países em desenvolvimento, ... See full document
117
Genetic and Molecular Basis of Arrhythmias
... The cardiac sodium channel is the gene altered in LQT3 and in Brugada Syndrome. It was quite unexpected that an inward current defect would lead to prolongation of QT in- terval and therefore SCN5A was not one ... See full document
6
MOLECULAR CHARACTERIZATION OF INFLUENZA B VIRUS OUTBREAK ON A CRUISE SHIP IN BRAZIL 2012
... to influenza viruses, people should be advised that pre-existing major medical conditions (diabetes, chronic lung diseases, immunodeficiency) can increase the likelihood of ...risk of complications ... See full document
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J. Pediatr. (Rio J.) vol.83 número3 en v83n3a06
... episodes of RVGE in Belém were caused by G9 serotype and thus provided an opportunity to assess the performance of the vaccine in a setting where a heterologous RV strain was ... See full document
8
Diverse Uses of Feathers with Emphasis on Diagnosis of Avian Viral Infections and Vaccine Virus Monitoring
... presence of retroviruses in ...material of an infected bird. For that reason the transmission of retroviruses by air is not trivial and was considered relatively unimportant, although avian leucosis ... See full document
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A Review of Approaches Targeting the Replacement of Coccidiostat Application in Poultry Production
... effects of polysaccharide extracts from two mushrooms, namely Lentinus edodes and Tremella fuciformis, and from a herb known as Astragalus ...impact of the polysaccharides on cellular and humoral immunity ... See full document
14
Phylodynamics and molecular evolution of influenza A virus nucleoprotein genes in Taiwan between 1979 and 2009.
... number of infections for this period and that the recent rise during 2002–2005, inferred in the BSP, could be a consequence of denser sampling after monitoring influenza activity started in 2000 ... See full document
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Immune Response in Cattle Vaccinated against Rabies
... 88.2% of the animals which received a booster dose of Fuenzalida and Palacios modi- fied vaccine one year after the first vaccination with ERA vaccine presented a titre of > 25 in the neu- ... See full document
6
Molecular findings from influenza A(H1N1)pdm09 detected in patients from a Brazilian equatorial region during the pandemic period
... and molecular diagnosis - Clini- cal specimens (combined nose and throat swabs or lung tissue fragments of deceased subjects) were collected from outpatients and hospitalised patients in Recife and its ... See full document
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