[PDF] Top 20 PLASMODIUM FALCIPARUM RESPONSE TO CHLOROQUINE IN THE AMERICAS
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PLASMODIUM FALCIPARUM RESPONSE TO CHLOROQUINE IN THE AMERICAS
... In addition, recru- descence of infection has been observed in the first seven days or in infections in which the parasitemia is not con- trolled in the same perio[r] ... See full document
2
Emerging Plasmodium vivax resistance to chloroquine in South America: an overview
... from the monkey-adapted Belem strain. In doing so, these authors demonstrated that it is feasible to perform WGS of ...throughout the genome that will enable large-scale geno- typing studies ... See full document
6
Pfcrt haplotypes and the evolutionary history of chloroquine-resistant Plasmodium falciparum
... calculated the geographic distance be- tween the capital cities in each pair of countries and cal- culated the genetic distance utilising the online computer program IBDSW ...evidence ... See full document
6
Real-time imaging of the intracellular glutathione redox potential in the malaria parasite Plasmodium falciparum.
... changes in the cytosolic glutathione redox potential of the malaria parasite Plasmodium ...falciparum. The sensor allows live cell spatiotemporal resolution of the ... See full document
18
J. Braz. Chem. Soc. vol.20 número4
... for in vitro activity against chloroquine-sensitive Plasmodium falciparum 3D7, Trypanosoma brucei rhodesiense STIB900 and Leishmania donovani ...developed in order to compare ... See full document
16
In vivo selection of plasmodium falciparum parasites carrying the chloroquine-susceptible pfcrt K76 allele after treatment with artemether-lumefantrine in Africa
... K76 in the recurrent infections ob- served in the present study is consistent with earlier in vitro data supporting a role for this gene in ...P. falciparum susceptibility ... See full document
8
Effect of transmission reduction by insecticide-treated bednets (ITNs) on antimalarial drug resistance in western Kenya.
... Despite the clear public health benefit of insecticide-treated bednets (ITNs), the impact of malaria transmission-reduction by vector control on the spread of drug resistance is not well ... See full document
10
Atovaquone and Proguanil Hydrochloride Compared with Chloroquine or PyrimethamineSulfadoxine for Treatment of Acute Plasmodium falciparum Malaria in Peru
... 1995, to May, 1996, in Piura, a medium-sized city in northern Peru where malaria is ...of the area and were considered ...uncomplicated falciparum malaria were eligible for the ... See full document
6
Plasmodium falciparum in the southeastern Atlantic forest: a challenge to the bromeliad-malaria paradigm?
... related to landscape modification, particularly by agriculture, which suggests that human modification of natural environments significantly increases the risk of infectious disease outbreaks, causing ... See full document
12
The role of pfmdr1 in Plasmodium falciparum tolerance to artemether-lumefantrine in Africa
... carrying the 1246D allele among reinfecting parasites, although not statistically significant (P ¼ ...due to the established high frequency already at ...of the combined 86N/1246D hapl- otype ... See full document
7
Commercial drugs containing flavonoids are active in mice with malaria and in vitro against chloroquine-resistant Plasmodium falciparum
... increased in the second half of the 20th century, prompting the change in malaria treatment from chloroquine to sulfadoxine/pyri- methamine and then to ... See full document
6
In Vitro Chloroquine Resistance Modulation Study on Fresh Isolates of Brazilian Plasmodium falciparum: Intrinsic Antimalarial Activity of Phenothiazine Drugs
... needed to check the pro- posed mechanistic hypothesis, we believe our findings are important to demonstrate the antiplasmodial effect of phenothiazine drugs at concentrations lower than those ... See full document
8
Sequence analysis of coding DNA fragments of pfcrt and pfmdr-1 genes in Plasmodium falciparum isolates from Odisha, India
... resulting in ap- proximately 300 million new cases and causing approxi- mately ...across the globe (WHO ...by Plasmodium falciparum, a protozoan parasite that com- pletes its sexual life cycle ... See full document
7
Cad. Saúde Pública vol.22 número12
... were to investigate the molecular basis for Plasmodium falciparum resistance to chloroquine in isolates from the Brazilian Amazon and to identify polymor- ... See full document
9
Genetics of chloroquine-resistant malaria: a haplotypic view
... across the continent. The high prevalence of the S tct VMNT haplotype in South Ameri- can countries is attributed to many factors, such as (i) the absence of CQ pressure, (ii) ... See full document
15
Efficient measurement of opsonising antibodies to Plasmodium falciparum merozoites.
... phagocytosis response was observed for merozoites opsonised with immune plasma, with low levels of background EtBr positive cells observed with non-immune plasma (Figure ...equivalent to non-opsonised ... See full document
10
A Sowunmi+ , AA Adedeji, GO Gbotosho, BA Fateye, TC Happi
... resistance to chloroquine (CQ) increases in ex- tent and severity, alternative regimens available to con- trol programmes in developing endemic countries in- cluding ... See full document
7
KF Vasconcelos, CV Plowe, CJ Fontes, D Kyle, DF Wirth, LH Pereira da Silva, MG Zalis
... Resistance to this drug emerged rapidly and different studies have dem- onstrated the widespread prevalence of the DHFR Asn-108 mutation which confers moderate resis- tance to pyrimethamine ... See full document
8
Luiz Hildebrando P da Silva
... on the erythrocyte membrane. Sera from symptomatic patients recognised the protein product of PF3D7_0533100, annotated as PfEMP1 ...of the iRBC membrane and is highly associated with malaria ... See full document
7
Luiz Hildebrando P da Silva
... is the main target of naturally acquired antibodies and is associated with protection from age-related clinical manifestations in symptomatic infections (Chan et ...examined the differences in ... See full document
7
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