[PDF] Top 20 Probing the informational and regulatory plasticity of a transcription factor DNA-binding domain.
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Probing the informational and regulatory plasticity of a transcription factor DNA-binding domain.
... their binding sites must have enough information to be distinguishable from all other sequences in the genome, and (2) they must bind these sites with an affinity that appropriately modulates ... See full document
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Role of cysteines in the stability and DNA-binding activity of the hypochlorite-specific transcription factor HypT.
... the DNA-binding domain in the correct position for efficient DNA-binding ...HypT DNA-binding (i.e., oxidation in vitro), Cys4 becomes oxidized and ... See full document
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High-precision, in vitro validation of the sequestration mechanism for generating ultrasensitive dose-response curves in regulatory networks.
... In the above studies molecular beacons served as a convenient, synthetic toolkit to quantitatively and precisely test the sequestra- tion ...themselves of any specific biological ...test ... See full document
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MYT3, a Myb-like transcription factor, affects fungal development and pathogenicity of Fusarium graminearum.
... members of the Myb protein family, MYT1 and MYT2, in Fusarium ...MYT1 and MYT2 are involved in female fertility and perithecium size, ...knowledge of Myb proteins in F. ... See full document
10
DNA-MATRIX: a tool for constructing transcription factor binding sites Weight matrix
... for the development of computational methods for motif ...number of motif finding algorithms have been implemented and applied to various motif models over the past few ...identify ... See full document
3
A structural-based strategy for recognition of transcription factor binding sites.
... given factor has a well-characterized PWM, it is straightforward to identify potential ...set of sequences thought to contain a common motif exists, de novo motif discovery approaches can be used to ... See full document
10
Co-localization of the oncogenic transcription factor MYCN and the DNA methyl binding protein MeCP2 at genomic sites in neuroblastoma.
... MYCN and MeCP2 can co- operate to regulate gene expression by altering higher-order chromatin ...to the promoter of active genes, indicating that a chromatin loop forms to allow the adjacent ... See full document
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Two residues in the basic region of the yeast transcription factor Yap8 are crucial for its DNA-binding specificity.
... recognize the Y8RE (Figure 5A). This finding, together with the fact that Yap1 nuclear sequestration is activated under arsenic stress, raises the question of why this transcription ... See full document
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Uncovering MicroRNA and Transcription Factor Mediated Regulatory Networks in Glioblastoma.
... DCX, and CACNA1E) belonged to GMB-related genes and 7 (FOSB, FOSL1, NFE2L1, NR4A2, SMAD4, TCF12, and YY1) belonged to human ...Among the 8 GBM-related genes, NOTCH2 and MET have been ... See full document
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Comprehensive human transcription factor binding site map for combinatory binding motifs discovery.
... know the map between transcription factors (TFs) and their binding sites is essential to reverse engineer the regulation ...10%–20% of the transcription ... See full document
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A linear model for transcription factor binding affinity prediction in protein binding microarrays.
... TF binding specificity based on PBM ...data and metrics from the DREAM5 transcription factor/DNA motif recognition challenge, our model can also be applied in less artificial ... See full document
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N-termini of fungal CSL transcription factors are disordered, enriched in regulatory motifs and inhibit DNA binding in fission yeast.
... in the same biological processes (adhesion, cell-cycle regulation, ploidy main- tenance), but their roles in these processes seem to be ...antagonistic. The relative levels of both Cbf11 and ... See full document
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Interactions between the R2R3-MYB transcription factor, AtMYB61, and target DNA binding sites.
... on the model of AtMYB61, the molecular interactions shared between the binding sites of AtMYB61 to its targets supported in vitro binding data (Figure ...AtMYB61 ... See full document
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Multi-species comparative analysis of the equine ACE gene identifies a highly conserved potential transcription factor binding site in intron 16.
... control of blood pressure. The human ACE gene contains an intronic Alu indel (I/D) polymorphism that has been associated with variation in serum enzyme levels, although the functional mechanism has ... See full document
10
Differential methylation of the HPV 16 upstream regulatory region during epithelial differentiation and neoplastic transformation.
... 7008–124) of the HPV16 reference clone (sequence identical to that published in the GenBank under the accession number NC_001526) was PCR-amplified with Pfu polymerase (Stratagene) and ... See full document
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O papel do fator de transcrição POD-1 na regulação de SF-1 e LRH-1 em células tumorais...
... SF-1 foi inicialmente identificado como fator regulador de transcrição de várias enzimas esteroidogênicas, tais como P450SCC, CYP11B1 e CYP21 ativando diretamente o promotor desses genes através da sequência consenso ... See full document
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Joint Analysis of the Discount Factor and Payoff Parameters in Dynamic Discrete Choice Games
... independently of the discount factor and speci…cation of the remaining components of the payo¤ ...on the payo¤s as well as the dependence structure ... See full document
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Interaction of the transactivation domain of B-Myb with the TAZ2 domain of the coactivator p300: molecular features and properties of the complex.
... in the low micromolar range (1–10 m ...number of protein complexes involved in transcriptional and translational regulation [65], [69], [70], which is consistent with the require- ment to form ... See full document
12
Human Papillomavirus Type 18 cis-Elements Crucial for Segregation and Latency.
... that the segregation efficiency is determined solely by the E2BSs and that the transcription factor binding sites in the URR do not play an apparent role in ... See full document
24
The Impact of the Expansion of the Bolsa Familia Program on the Time Allocation of Youths And Their Parents Lia Chitolina Miguel Nathan Foguel Naercio Menezes-Filho
... household, the program caused an increase of more than 11 percentage points in the probability of attending ...in the estimated impact is the fact that his/her family is only ... See full document
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