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Tabela Suplementar 1 - Lista de genes diferencialmente expressos entre os modelos de superexpressão

de Dicer (dcr-1 o/e) ou Argonauta (alg-1 o/e), mutantes para isp-1 ou clk-1 e seus respectivos controles. Na tabela estão indicadas as vias nas quais os genes estão envolvidos e se os mesmos se encontram aumentados ou diminuídos em cada modelo. Vias: (1) Metabolismo de Carbono, (2) Mitocôndria, (3) Desenvolvimento Embrionário, (4) Reprodução, (5) Metabolismo de Glioxilato e Dicarboxilato, (6) Ciclo Celular, (7) Via das Pentoses-fosfato, (8) Ciclo dos Ácidos Tricarboxílicos, (9) Piridoxal Fosfato,

(10) Biossíntese de Aminoácidos, (11) Glicólise, (12) Metabolismo de Tirosina, (13) Determinação do

Tempo de Vida, (14) Splicing Alternativo, (15) Ribossomo, (16) Tradução, (17) Enzimas que utilizam NAD como Substrato, (18) Regulação da Tradução, (19) Metabolismo de Arginina e Prolina, (20) Gliconeogênese, (21) Degradação de Ácidos Graxos, (22) Metabolismo de Purinas, (23) Metabolismo de Glicina, (24) Fasciculação Axonal, (25) Proteína de Auto renovação de Células Tronco Piwi, (26) Metabolismo de Glicina, Serina e Treonina, (27) Regulação Negativa da Sinalização da Proteína Quinase C, (28) Reparo de DNA por 'mismatch', (29) Balsas Lipídicas, (30) Regulação do Estabelecimento da Polaridade Celular (31) RNA de interferência. AUM = gene com expressão aumentada, DIM = gene com expressão diminuída.

Nome do Gene Vias em que

está envolvido

dcr-1 o/e

alg-1

o/e clk-1 isp-1

10-formyltetrahydrofolate dehydrogenase(alh-3) AUM 2 (Zwei) IG domain protein(zig-6) AUM

2,3-bisphosphoglycerate-independent phosphoglycerate mutase(ipgm-1) (1) (3) (4) (10) (11) (13) (14) (23) (26) AUM AUM

26S proteasome non-ATPase regulatory subunit 6(rpn-7) (3) (4) (13) DIM

28S ribosomal protein S7, mitochondrial(mrps-7) (2) (15) (16) DIM 4-hydroxyphenylpyruvate dioxygenase(hpd-1) (12) (13) AUM 60S ribosomal protein L13a(rpl-16) (3) (15) (16) DIM

60S ribosomal protein L19(rpl-19) (3) (4) (13) (15)

(16) DIM

60S ribosomal protein L36(rpl-36) (3) (4) (15) (16) DIM 60S ribosomal protein L37a(rpl-43) (3) (15) (16) DIM

ABC Transporter family(abt-1) AUM Acetyl-CoA acetyltransferase homolog, mitochondrial(kat-1) (1) (2) (5) (21) AUM ACEtyl-CoA Regulator(acer-1) (2) AUM

Adenylate kinase(let-754) (2) (3) (4) (22)

(27) (30) (31) DIM DIM Adenylosuccinate synthetase(adss-1) (3) (4) (22) AUM

Alcohol dehydrogenase 1(sodh-1) (12) (13) (17) AUM Alcohol dehydrogenase class-3(H24K24.3) (1) (12) (14) (17) AUM Alcohol/Ribitol Dehydrogenase family(ard-1) (4) AUM

ALP/Enigma encoding(alp-1) (13) (31) AUM

Alpha-1,4 glucan phosphorylase(T22F3.3) (3) (9) AUM alpha-CaTuliN (catenin/vinculin related)(ctn-1) AUM Aminomethyltransferase(gcst-1) (1) (5) (23) (26) AUM

Annexin(nex-1) AUM

APYrase(apy-1) (4) (13) (22) AUM AQuaPorin or aquaglyceroporin related(aqp-2) DIM

ARGinine Kinase(argk-1) (19) DIM Aspartate aminotransferase(got-2.1) (1) (2) (4) (10)

(12) (19) DIM Aspartate aminotransferase(got-2.2) (1) (2) (10) (12)

(19) AUM

ASpartyl Protease(asp-4) AUM

ATP synthase subunit alpha, mitochondrial(H28O16.1) (2) (3) (4) (13)

(14) AUM

ATP synthase subunit(atp-3) (2) (3) (4) (13) AUM ATP-dependent (S)-NAD(P)H-hydrate dehydratase(R107.2) (17) DIM

ATP-dependent DNA helicase II subunit 2(cku-80) AUM AuTophaGy (yeast Atg homolog)(atg-18) (3) (13) AUM BLOC (Biogenesis of Lysosome-related Organelles Complex) and

n(blos-7) DIM

BRCA1-associated RING domain protein 1(brd-1) AUM Ca(2+)/calmodulin-dependent protein kinase phosphatase(fem-

2) (3) (4) DIM

Cadherin-related hmr-1(hmr-1) (3) (4) (14) (24) DIM

CaDmium Responsive(cdr-2) AUM AUM Caenorhabditis GTP-binding Protein(cgp-1) DIM

Calcium Channel, Alpha subunit(cca-1) DIM

Calcium-transporting ATPase(mca-3) (3) DIM cAMP-dependent protein kinase regulatory subunit(kin-2) (4) (14) (27) (30) DIM

CarboxyPeptidase D family(cpd-1) DIM Carboxypeptidase(K10C2.1) (29) DIM DIM

Cathepsin B-like cysteine proteinase 4(cpr-4) AUM Cathepsin B-like cysteine proteinase 6(cpr-6) AUM AUM

CathePsin Z(cpz-1) (3) AUM

Cation transporting ATPase(catp-1) DIM Cell Division Cycle related(cdc-5L) (3) (4) (6) DIM

Chitinase-like protein C25A8.4(cht-3) AUM

CHItinase-Like(chil-20) AUM

CILiary localization(cil-7) (3) DIM

COLlagen(col-53) DIM DIM DIM

COP9 signalosome complex subunit 4(csn-4) (3) (4) DIM

C-type LECtin(clec-209) AUM

C-type LECtin(clec-63) AUM AUM

Cuticle collagen 8(col-8) AUM

CUTiclin-Like(cutl-4) AUM DIM Cytochrome b-c1 complex subunit 1, mitochondrial(ucr-1) (2) (3) (4) (13) AUM

CYtochrome P450 family(cyp-33C11) DIM

CYtochrome P450 family(cyp-33C8) AUM Cytoplasmic dynein 2 heavy chain 1(che-3) DIM DAF-16/FOXO Controlled, germline Tumor affecting(dct-18) AUM AUM

DeHydrogenases, Short chain(dhs-11) AUM

DeHydrogenases, Short chain(dhs-14) AUM

DeHydrogenases, Short chain(dhs-28) AUM Delta(9)-fatty-acid desaturase fat-6(fat-6) (3) (4) (13) (14) DIM

Diacylglycerol kinase AUM

Dicer Related Helicase(drh-3) (3) DIM DIM Discoidin domain-containing receptor tyrosine kinase B(ddr-2) (14) AUM DNA-directed RNA polymerase II subunit RPB1(ama-1) (3) (4) (22) AUM DNaJ domain (prokaryotic heat shock protein)(dnj-27) AUM AUM Dolichyl-diphosphooligosaccharide--protein glycosyltransferase

subunit stt-3(stt-3) (3) (4) DIM DreBriN 1/DreBriN-like (where Drebrin is from Developmentally

REgulated BRaIN protein) family homolog(dbn-1) DIM DIM E3 ubiquitin-protein ligase(wwp-1) (3) (13) (24) AUM AUM Elongation factor Ts, mitochondrial(tsfm-1) (2) (3) (4) (16) AUM AUM EMC Endoplasmic Membrane protein Complex (yeast EMC)

homolog(emc-1) DIM

Endogenous-RNAi deficient arGOnaute(ergo-1) (18) (25) DIM ENhancer of Uncoordination(enu-3.3) (13) AUM

Enolase(enol-1) (1) (3) (4) (10)

(11) (13) (14) AUM AUM Enoyl-CoA Hydratase(ech-4) (21) AUM AUM Enoyl-CoA Hydratase(ech-7) (2) (21) AUM EPHeXin (Eph-interacting GEF) homolog(ephx-1) (4) AUM Eukaryotic translation initiation factor 3 subunit L(C17G10.9) (14) (16) AUM

Eukaryotic translation initiation factor 5A-2(iff-2) (3) (4) (16) DIM

Eukaryotic translation initiation factor 6(eif-6) (3) (4) (16) DIM eXPOrtin (nuclear export receptor)(xpo-2) (3) (4) DIM F-actin-capping protein subunit alpha(cap-1) (3) (4) AUM

F-actin-capping protein subunit beta(cap-2) (3) (4) DIM

fatty Acid CoA Synthetase family(acs-11) AUM fatty Acid CoA Synthetase family(acs-2) (2) AUM AUM

F-box A protein(fbxa-219) DIM

F-box A protein(fbxa-48) DIM

F-box/WD repeat-containing protein lin-23(lin-23) (3) (6)(13) DIM

Female germline-specific tumor suppressor gld-1(gld-1) (3) (4) (13) (18) DIM FERM domain (protein4.1-ezrin-radixin-moesin) family(frm-1) DIM

FERM domain (protein4.1-ezrin-radixin-moesin) family(frm-2) (31) AUM AUM FIdGetin-Like (mammalian developmental AAA ATPase)

related(figl-1) (3) (4) (6) AUM FiLamiN (actin binding protein) homolog(fln-1) (3) (4) (24) AUM FiLamiN (actin binding protein) homolog(fln-1) (3) (4) (24) AUM

Folate-like transporter 2(folt-2) AUM

Fructose-1,6-BiPhosphatase(fbp-1) (1) (7) (20), AUM Fructose-bisphosphate aldolase 1(aldo-1) (1) (7) (10) (11)

(13) AUM AUM

FUcosyl Transferase(fut-5) DIM

FumarylAcetoacetate Hydrolase(fah-1) (3) (4) (12) AUM G Protein, Alpha subunit(gpa-13) DIM AUM

Galectin(lec-2) (29) AUM AUM

Galectin(lec-2) (29) AUM AUM

Galectin(lec-6) AUM

Gamma-tubulin Interacting Protein(gip-1) (3) AUM AUM Gastrulation defective protein 1(gad-1) (3) AUM GIT1 (mammalian G protein-coupled receptor kinase InTeractor

1) homolog(git-1) AUM

Glucose-6-phosphate isomerase(gpi-1) (1) (3) (7) (11)

(13) (20), AUM

GLuCuronosylTransferase-like(glct-6) (13) AUM GLYcosylation related(gly-10) (14) DIM DIM Grip (GRIP) and Coiled-Coil domain containing protein

related(gcc-1) AUM AUM

HEAT repeat-containing protein 1 homolog(toe-1) (3) DIM Heat shock 70 kDa protein F, mitochondrial(hsp-6) (2) (3) (4) (13) AUM Heat Shock Protein(hsp-43) AUM AUM AUM Heavy chain, Unconventional Myosin(hum-1) DIM Heavy chain, Unconventional Myosin(hum-4) AUM

High Incidence of Males (increased X chromosome loss)(him-4) AUM Histone acetyltransferase(mys-2) DIM DIM

Histone DeAcetylase(hda-11) AUM Histone-lysine N-methyltransferase(met-1) (4) (13) DIM

Homeobox protein cut-like ceh-44(ceh-44) (14) DIM human FANCD2 (Fanconi's anemia defect) ortholog(fcd-2) (3) DIM

human SPG (spastic paraplegia)(spg-7) (2) (3) (4) (13) AUM

hypothetical protein(C01C4.2) DIM

hypothetical protein(C04G2.2) AUM

hypothetical protein(C09D4.3) DIM

hypothetical protein(C10C6.3) AUM

hypothetical protein(C14B1.9) (3) AUM

hypothetical protein(C17C3.15) AUM hypothetical protein(C17G10.2) (3) (4) AUM

hypothetical protein(C18E3.5) DIM

hypothetical protein(C18F10.7) DIM hypothetical protein(C27F2.8) (3) AUM hypothetical protein(C35E7.5) DIM

hypothetical protein(C41H7.4) (3) AUM

hypothetical protein(C46A5.4) AUM

hypothetical protein(C47B2.2) AUM

hypothetical protein(C47D2.1) AUM

hypothetical protein(C52E2.4) AUM hypothetical protein(C53D6.6) DIM

hypothetical protein(C53H9.2) (3) (4) DIM DIM

hypothetical protein(C55A1.6) AUM

hypothetical protein(D1081.7) (4) AUM

hypothetical protein(D2030.2) AUM

hypothetical protein(E01A2.1) DIM hypothetical protein(emb-4) (3) DIM

hypothetical protein(F01G4.4) (3) AUM

hypothetical protein(F02E9.10) DIM hypothetical protein(F07C3.3) DIM

hypothetical protein(F09F9.4) (3) (4) AUM AUM hypothetical protein(F14B6.2) AUM

hypothetical protein(F14D12.1) (31) DIM hypothetical protein(F14F7.5) AUM

hypothetical protein(F16C3.2) AUM

hypothetical protein(F19B10.2) AUM hypothetical protein(F25E2.2) (3) AUM hypothetical protein(F31C3.3) DIM DIM

hypothetical protein(F32D8.12) AUM hypothetical protein(F35E12.10) (29) AUM

hypothetical protein(F38A1.8) (3) (4) DIM

hypothetical protein(F38A5.2) AUM AUM hypothetical protein(F39C12.1) AUM

hypothetical protein(F41B4.3) DIM

hypothetical protein(F42H11.1) DIM

hypothetical protein(F46H5.2) AUM

hypothetical protein(F46H5.4) AUM

hypothetical protein(F46H5.7) AUM AUM

hypothetical protein(F53F1.2) AUM

hypothetical protein(F54F7.10) AUM

hypothetical protein(F54G2.2) DIM

hypothetical protein(F57B10.5) DIM hypothetical protein(F57F4.4) (29) AUM DIM hypothetical protein(H04D03.3) AUM

hypothetical protein(K03E5.2) DIM

hypothetical protein(K07H8.10) (3) DIM DIM hypothetical protein(K08C9.7) (24) AUM AUM

hypothetical protein(K08E4.6) DIM

hypothetical protein(K08H2.4) DIM

hypothetical protein(K09C8.2) DIM

hypothetical protein(K11H12.8) AUM AUM hypothetical protein(M02D8.3) AUM

hypothetical protein(M18.3) AUM

hypothetical protein(mlt-3) (13) AUM hypothetical protein(R08E5.3) AUM AUM hypothetical protein(R09F10.3) (3) (4) AUM hypothetical protein(R10E11.5) DIM hypothetical protein(R10E8.6) (3) AUM hypothetical protein(R11.3) DIM DIM

hypothetical protein(rsd-3) AUM

hypothetical protein(T02G5.7) (1) (2) (5) (21) AUM hypothetical protein(T06D8.2) (3) DIM

hypothetical protein(T07D3.9) AUM hypothetical protein(T12B3.4) DIM hypothetical protein(T20F5.6) AUM

hypothetical protein(T21B10.3) (3) AUM AUM hypothetical protein(T22B2.6) DIM

hypothetical protein(T22F3.2) DIM

hypothetical protein(T22F7.3) AUM

hypothetical protein(T23G11.7) AUM

hypothetical protein(T28B8.4) (3) DIM DIM hypothetical protein(T28C6.7) DIM

hypothetical protein(unc-70) (3) (13) (24) AUM

hypothetical protein(vab-10) (3) (4) DIM hypothetical protein(vab-10) (3) (4) DIM hypothetical protein(W01F3.2) AUM

hypothetical protein(W02B8.2) (3) DIM

hypothetical protein(W03F11.1) (4) DIM hypothetical protein(W08G11.1) DIM

hypothetical protein(W09C5.7) AUM

hypothetical protein(W09D10.1) AUM hypothetical protein(Y18H1A.9) AUM

hypothetical protein(Y26E6A.2) AUM

hypothetical protein(Y32B12B.2) DIM hypothetical protein(Y37A1B.5) AUM hypothetical protein(Y37E11AL.6) AUM

hypothetical protein(Y38F2AR.12) AUM hypothetical protein(Y39G8B.1) AUM hypothetical protein(Y39G8B.2) AUM hypothetical protein(Y40B1A.3) AUM AUM hypothetical protein(Y41C4A.11) AUM

hypothetical protein(Y43C5B.3) (16) DIM

hypothetical protein(Y43F8B.1) AUM

hypothetical protein(Y47A7.1) DIM

hypothetical protein(Y47D3A.31) DIM hypothetical protein(Y47G6A.22) AUM

hypothetical protein(Y51H7C.13) DIM hypothetical protein(Y52B11A.11) (3) DIM

hypothetical protein(Y62H9A.6) AUM

hypothetical protein(Y71H10B.1) (3) (4) (22) AUM

hypothetical protein(Y71H2AM.13) (31) AUM AUM hypothetical protein(Y82E9BR.21) DIM

hypothetical protein(Y95B8A.8) (24) AUM

hypothetical protein(ZC123.1) DIM

hypothetical protein(ZK1307.1) AUM

hypothetical protein(ZK380.4) AUM

hypothetical protein(ZK632.5) AUM hypothetical protein(ZK809.3) (3) (4) (13) AUM hypothetical protein(ZK829.7) AUM hypothetical protein(ZK909.3) (22) AUM Hypoxanthine PhosphoRibosylTransferase homolog(hprt-1) (22) DIM

IMportin Beta family(imb-1) (3) (4) AUM Increased Sodium Tolerance Related(istr-1) AUM INverted Formin/formin Three-related(inft-2) AUM

Isocitrate dehydrogenase [NAD] subunit, mitochondrial(idhg-2) (1) (2) (8) (10)

(17) AUM

Kynureninase(kynu-1) (9) AUM

Lamin-1(lmn-1) (3) (4) (13) AUM

Lim and Transglutaminase Domain(ltd-1) AUM L-lactate dehydrogenase AUM AUM

LONg(lon-1) (3) (4) AUM AUM

LysM Domain (peptidoglycan binding) protein(lmd-3) (13) DIM LYSosomal Trafficking regulator protein(lyst-1) AUM

Malate DeHydrogenase(mdh-1) (1) (2) (5) (8) (17) AUM Malate synthase(icl-1) (2) (8) (13) (14) AUM MATH (meprin-associated Traf homology) domain

containing(math-26) AUM

Mediator of RNA polymerase II transcription subunit 4(mdt-4) (3) AUM

Metabotropic GLutamate receptor family(mgl-2) (3) AUM Methylmalonic aciduria type A homolog, mitochondrial(mmaa-

1) (2) (3) (14) AUM

MethylMalonic Aciduria type B homolog(mmab-1) AUM MICOS complex subunit MIC60(immt-1) (2) AUM MiTochondrial Carrier Homolog(mtch-1) (2) (3) (13) AUM Mitochondrial Ribosomal Protein, Large(mrpl-28) (3) (15) DIM AUM

Mitogen-activated protein kinase mpk-1(mpk-1) (3) (4) (6)(13)

(14) AUM

Mitotic checkpoint serine/threonine-protein kinase bub-1(bub-

1) (3) (4) (6) AUM AUM

M-phase inducer phosphatase cdc-25.3(cdc-25.3) (6) DIM AUM

NeuReXin related(nrx-1) (13) AUM Nuclear hormone receptor family member nhr-55(nhr-55) AUM

Nuclear hormone receptor family member nhr-77(nhr-77) DIM NUCleoBindin homolog(nucb-1) DIM

NucleOLar protein(nol-1) (3) (4) (13) AUM DIM DIM OXidative stress Induced(oxi-1) AUM PAZ/PIWI domain-containing(ppw-1) (25) AUM PERMeable eggshell(perm-2) (3) (4) AUM

P-GlycoProtein related(pgp-10) AUM AUM Phosphatidate cytidylyltransferase, mitochondrial(Y71F9B.2) (2) AUM

Phosphoethanolamine MethylTransferase(pmt-1) (3) (4) DIM Phosphotransferase(hxk-3) (11) DIM

Piwi-like protein(wago-5) (25) DIM PLaSTin (actin bundling protein) homolog(plst-1) (3) AUM

Poly(U) Polymerase(pup-3) DIM

Prion-like-(Q/N-rich)-domain-bearing protein(pqn-59) (3) (4) DIM

Prion-like-(Q/N-rich)-domain-bearing protein(pqn-87) DIM DIM Prion-like-(Q/N-rich)-domain-bearing protein(pqn-87) DIM DIM Probable arginine kinase F46H5.3(F46H5.3) (14) (19) AUM AUM Probable ATP-dependent RNA helicase DDX55

homolog(ZK512.2) (4) DIM DIM

Probable electron transfer flavoprotein subunit alpha,

mitochondrial(F27D4.1) (2) (3) (4) AUM

Probable inorganic pyrophosphatase 1(pyp-1) (3) (4) (14) AUM Probable manganese-transporting ATPase catp-8(catp-8) AUM

Probable methylenetetrahydrofolate reductase(mthf-1) (1) (14) AUM Probable methylmalonyl-CoA mutase, mitochondrial(mmcm-1) (1) (2) (5) AUM

Probable NADH dehydrogenase [ubiquinone] flavoprotein 2,

mitochondrial(F53F4.10) (2) (3) (17) DIM Probable ornithine aminotransferase, mitochondrial(C16A3.10) (2) (9) (19) AUM

Probable phosphoribosylformylglycinamidine synthase(F10F2.2) (22) AUM Probable succinyl-CoA ligase [ADP/GDP-forming] subunit alpha,

mitochondrial(sucl-1) (1) (2) (3) (8) DIM AUM AUM Propionyl-CoA carboxylase alpha chain, mitochondrial(pcca-1) (1) (2) (5) AUM Proteasome subunit alpha type-1(pas-6) (3) (4) (13) AUM Protein kinase C(pkc-2) (14) DIM Protein phosphatase ppm-1(ppm-1) (14) AUM Protein unc-33(unc-33) (14) AUM

Protein ver-1(ver-1) AUM AUM

Protein-tyrosine-phosphatase(T20B6.1) AUM Protein-tyrosine-phosphatase(Y113G7C.1) (3) AUM Pumilio domain-containing protein 12(puf-12) (3) (4) (18) DIM

Pumilio domain-containing protein 7(puf-7) (6)(18) AUM Putative 28S ribosomal protein S5, mitochondrial(mrps-5) (2) (3) (15) (16) AUM

Putative metalloproteinase inhibitor tag-225(cri-2) AUM AUM Putative syntaxin-5(syx-5) (3) (4) DIM

PYruvate Carboxylase(pyc-1) (1) (2) (10) (13)

(20), DIM

RAB family(rab-1) (3) (4) AUM

RAB family(rab-28) DIM

Ran GTPase-activating protein 2(ran-2) (3) (4) (6)(14) DIM

Regulator of chromosome condensation(ran-3) (3) (4) (6) DIM Replication factor C subunit 4(rfc-4) (3) (4) (28) DIM

Replication Protein A homolog(rpa-4) (28) DIM

Reticulon-4-interacting protein 1, mitochondrial(rad-8) (2) (3) (4) AUM RhOMboid (Drosophila) related(rom-4) DIM DIM Ribonucleoside-diphosphate reductase small chain(rnr-2) (3) (4) (22) DIM AUM

Ribosomal Protein, Large subunit(rpl-30) (3) (4) (13) (15)

(16) DIM

Ribosomal Protein, Large subunit(rpl-32) (4) (15) (16) DIM AUM Ribosomal Protein, Small subunit(rps-24) (4) (15) (16) DIM

Ribosome production factor 2 homolog(Y54E10A.10) (4) DIM RNA-dependent RNA polymerase Family(rrf-3) (3) (4) AUM AUM

Serine hydroxymethyltransferase(mel-32)

(1) (2) (3) (5) (9) (10) (14) (23)

(26)

AUM AUM

Serine Palmitoyl Transferase famiLy(sptl-1) (3) (9) AUM Serine/threonine-protein kinase plk-2(plk-2) AUM

Serine--pyruvate aminotransferase(agxt-1) (1) (5) (9) (23)

(26) AUM

SET (trithorax/polycomb) domain containing(set-5) (13) AUM SKI (yeast SuperKIller) Helicase homolog(skih-2) AUM

SLC (SoLute Carrier) homolog(slc-25A10) (16) AUM Small Glutamine-rich Tetratrico repeat protein(sgt-1) (3) (4) AUM

Solute carrier organic anion transporter family

member(F21G4.1) AUM

Spindle-defective protein 5(spd-5) (3) (4) (6) DIM SR Protein Kinase(spk-1) (3) (4) (14) AUM SR protein related(rsr-2) (3) (4) (13) DIM Structural maintenance of chromosomes protein 1(him-1) (3) (4) (6)(14) DIM Succinate dehydrogenase [ubiquinone] flavoprotein subunit,

mitochondrial(sdha-1) (1) (2) (3) (8) AUM Suppressor of Ectopic Unc-5(seu-1) DIM

SYMpleKin cleavage and polyadenylation factor(symk-1) (3) (13) DIM T Cell Lineage defect(tcl-2) AUM TAF (TBP-associated transcription factor) family(taf-6.2) (3) (4) DIM

Target of rapamycin homolog(let-363) (3) (4) (13) (14)

(16) (18) DIM DIM TATA box-binding protein-associated factor RNA polymerase I

subunit B(F23H11.2) (4) AUM

TeNSin homolog(tns-1) DIM

THO Complex (transcription factor/nuclear export) subunit(thoc-

1) AUM

TransALDolase-1 homolog(tald-1) (1) (7) (10) (31) AUM AUM Transcription elongation factor SPT5(spt-5) (3) (4) DIM

Transcription initiation factor TFIID subunit 1(taf-1) (3) (4) AUM Transient receptor potential channel(gon-2) (4) DIM

TransKeTolase homolog(tkt-1) (1) (3) (4) (7) (10)

(13) AUM

Translationally-controlled tumor protein homolog(tct-1) (3) (4) DIM TWiNKle mtDNA helicase homolog AUM

Tyrosine-protein kinase receptor ver-3(ver-3) DIM Tyrosine-protein kinase(C25A8.5) AUM

Tyrosine-protein kinase(K09B11.5) DIM Tyrosine-protein kinase(kin-26) AUM

Ubiquinol-Cytochrome c oxidoReductase complex(ucr-2.3) (3) (4) AUM

Ubiquitin-Like Protease(ulp-2) (3) (4) AUM Uncharacterized GTP-binding protein C02F5.3(C02F5.3) AUM AUM

Uncharacterized protein AUM

VIG (Drosophila Vasa Intronic Gene) ortholog(vig-1) (3) DIM ViGiLN homolog(vgln-1) (3) (4) AUM

Vitellogenin-1(vit-1) AUM

Vitellogenin-6(vit-6) (14) AUM

Anexos

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