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SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling.

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Academic year: 2017

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Fig 1. Sdccag8 gt/gt mice exhibit rib cage and pre-axial polydactyly phenotypes. (A–D) Skeletal preparation of E18.5 rib cage and hind limbs, demonstrate misalignment (red arrows) of sternum ossification centers in Sdccag8 gt/gt embryos (A), when compared
Fig 2. Sdccag8 is required or cilia formation and Hh signaling. (A,B) Sdccag8 gt/gt cells have shorter cilia.
Table 1. Identification of human SDCCAG8 complex proteins a .
Fig 3. SDCCAG8 associates with a characteristic set of proteins at the centrosome. (A) The Sdccag8 interacting proteins discovered by SILAC as centrosomal components belong to 4 functional groups, i.e.
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