Volume 8
Supplement 1
November 2010
JOURNAL OF
TRANSLATIONAL MEDICINE
5th European Workshop on Immune-Mediated
Inl ammatory Diseases
Sitges-Barcelona, Spain
1-3 December 2010
Meeting abstracts
Editors
Dominique L Baeten
Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands
Ricardo Pujol-Borrell
Blood and Tissue Bank, Laboratory of Immunobiology for Research and Application to Diagnosis (LIRAD), Health Science
Research Institute ‘Germans Trias i Pujol’, Badalona (Barcelona), Spain
Workshop Chairs
Juan D Cañete
Arthritis Unit, Rheumatology Dept., Hospital Clinic de Barcelona, Barcelona, Spain
Francisco Lozano
Servei d’Immunologia, Hospital Clínic de Barcelona, Barcelona, Spain
Organizing Steering Committee
Dominique Baeten, Amsterdam, The Netherlands
Juan D Cañete, Barcelona, Spain
João Eurico Fonseca, Lisboa, Portugal
Francisco Lozano, Barcelona, Spain
Jose Pablos, Madrid, Spain
Antonio Puccetti, Genua, Italy
Ricardo Pujol-Borrell, Barcelona, Spain
Alberto Sanchez-Fueyo, Barcelona, Spain
Martin van Hagen, Rotterdam, The Netherlands
Volume 8
Supplement 1
November 2010
JOURNAL OF
TRANSLATIONAL MEDICINE
Contents
INVITED LECTURES (I1-I17)
I1 Immunosurveillance by gamma delta T cells - lessons from the cancer field
AC Hayday, E Binda, A Robert, M Serrano and F Dieli
I2 A genomic approach to biomarker discovery in human autoimmune diseases
V Pascual
I3 Skin-derived tumor specific T cells predict clinical outcome in dendritic cell vaccination studies in both stage III and IV melanoma patients
EHJG Aarntzen, W J Lesterhuis, M Van Rossum, GJ Adema, CF Figdor, CJA Punt and IJM De Vries
I4 HLA guided epitope discovery in Type 1 diabetes to generate novel therapeutics
M Peakman
I5 GWAS in IMIDs RM Plenge
I6 Crohn’s disease is caused by a failure of the innate immune response with major abnormalities in macrophage biology AW Segal
I7 RNA interference and viruses in mammalian cells B Monsef
I8 MicroRNAs in the context of human diseases E Sonkoly
I9 Human T helper cells in immunity and autoimmunity: Th17 and beyond
F Sallusto
I10 Exploring new inflammatory pathways in the synovium IB McInnes
I11 Primary antibody deficiencies in the context of normal B-cell differentiation
M van der Burg
I12 Early-onset inflammatory bowel disease caused by mutant IL10 receptor
EO Glocker, D Kotlarz , K Boztug , EM Gertz, AA Schäffer, F Noyan, M Perro, J Diestelhorst, A Allroth, D Murugan, N Hätscher, D Pfeifer, KW Sykora, M Sauer, HI-eipe, M Lacher, R Nustede, C Woellner, U Baumann, U Salzer, S Koletzko, N Shah, AW Segal, A Sauerbrey, S Buderus, SB Snapper, B Grimbacher and C Klein
I13 Chemokines as inflammatory mediators of fibrosis in liver fibrosis
HE Wasmuth
I14 Biomarkers inform clinical trials and pathogenesis in systemic sclerosis
R Lafyatis
I15 Mechanisms of accelerated atherosclerosis associated with IMIDs
Z Mallat
I16 Understanding the molecular bases of tissue inflammation RA Flavell
ORAL PRESENTATIONS (O1-O8)
O1 Identification of novel genetic markers associated with the clinical phenotypes of systemic sclerosis through a genome wide association strategy
O Gorlova, JM Martin , B Rueda , BPC Koeleman , J Ying, M Teruel, LM Diaz-Gallo, JC Broen, MC Vonk, CP Simeon, BZ Alizadeh, MJH Coenen, AE Voskuyl, AJ Schuerwegh, PLCM van Riel, M Vanthuyne, R van ‘t Slot, A Italiaander, RA Ophoff, N Hunzelmann, V Fonollosa, N Ortego-Centeno, MA González-Gay, FJ García-Hernández, MF González-Escribano, P Airo, J van Laar, J Worthington, R Hesselstrand, V Smith, F De Keyser, F Houssiau, MM Chee, R Madhok, P Shiels, R Westhovens, A Kreuter, E de Baere, T Witte, L Padyukov, A Nordin, R Scorza, C Lunardi, BA Lie, A M Hoffmann-Vold, P García de la Peña, P Carreira, J Varga, M Hinchcliff, AT Lee, P Gourh, CI Amos, G Riemekasten, A Herrick, L Beretta, C Fonseca, CP Denton, PK Gregersen, S Agarwal, S Assassi, FK Tan, FC Arnett , TRDJ Radstake, MD Mayes and J Martin
O2 Linking genotype to cell function in chronic inflammation: analysis of the IL-23/Th17 axis in spondylarthropathy M Roumier, M Coffre, H Law, C Salliot, M Dougados, E Bianchi and L Rogge
O3 Cytosolic phospholipase A2α gene silencing in monocytes alters development of Th1 responses and reduces autoimmune arthritis
G Courties, J Presumey, M Baron, V Escriou, P Van Lent, D Scherman, A Cantagrel, W Van den Berg, C Jorgensen, J-L Davignon and F Apparailly
O4 RANKL expression in human T-lymphocytes requires cooperative signaling through the T-cell receptor and adhesion molecule CD2
BP Harvey and Z Kaymakcalan
O5 Single-cell analysis techniques reveal a striking heterogeneity of human CD4+ T cell subsets
O6 Sustained T cell Rap1 activation protects against Experimental Autoimmune Encephalomyelitis (EAE) via modulation of T cell responses
G Franco Salinas, S Krausz, W Dontje, PP Tak, D Baeten and K Reedquist
O7 Skewed X-chromosomal inactivation impacts T regulatory cell function in systemic sclerosis
JCA Broen, ILM Wolvers-Tettero, L Geurts-van Bon, MC Vonk, MJH Coenen, R Lafyatis, TRDJ Radstake and AW Langerak
O8 Fra-1 regulates inflammatory and degenerative arthritis T Kireva, K Zwerina, W Baum, S Hayer, G Schett and J Zwerina
POSTER PRESENTATIONS (P1-P73)
P1 The neonatal Fc receptor is expressed by human lymphocytes K van Bilsen, J Bastiaans, WA Dik, EF De Haas, SG Baarsma, RW Kuipers, PM van Hagen
P2 Differential association of two PTPN22 coding variants with
Crohn’s disease and ulcerative colitis LM Diaz-Gallo
P3 Single-cell gene profiling analysis of human regulatory T cell subsets
S Maiella, S Dong, C Becavin, M Coffre, K Placek, E Bianchi, A Benecke, L Rogge
P4 TLR signals modify the expression of scavenger receptors C Zamora, E Cantó, JC Nieto, C Juarez, S Vidal
P5 A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with Systemic Sclerosis in a large European cohort
B Rueda
P6 IMID-Biobank: Biobank of immune-mediated inflammatory diseases (IMIDs)
S Marsal, J Cañete, J Tornero, A Fernandez-Nebro, JM Hernanz, J Panes, A Julià, R Tortosa
P7 Genetic polymorphisms of inflammatory molecules in Tunisian inflammatory bowel diseases
Y Gorgi, W Ben Aleya, D Khazen, I Sfar, H Aounallah-Skhiri, L Mouelhi, S Jendoubi-Ayed, M Makhlouf, T Ben Rhomdhane, S Matri, A Filali, H Aouadi, T Najjar, K Ayed, T Ben Abdallah
P8 Cytokines and apoptosis genes polymorphisms influence the outcome of hepatitis C virus infection
L Ksiaa-Cheikh Rouhou, I Sfar, H Aounallah-Skhiri, H Aouadi, S Jendoubi-Ayed, T Ben Abdallah, K Ayed, Y Lakhoua-Gorgi
P9 Lack of adalimumab’s complement dependent cytotoxicity on human cells expressing complement regulatory proteins KM Grebe, J Salfeld, Z Kaymakcalan
P10 Efficacy of adalimumab in sarcoidosis
LSJ Kamphuis, WK Lam-Tse, WA Dik, J Bastiaans, P van Biezen, PLA van Daele, DJ Kwekkeboom, RWAM Kuijpers, GS Baarsma, PM van Hagen, H Hooijkaas, JAM van Laar
P11 Differences in virus prevalence and load in the hearts of patients with chronic dilated cardiomyopathy with and without immune-mediated inflammatory disease R Dennert, P van Paassen, C Bruggeman, P Wolffs, JW Cohen Tervaert, S Heymans
P12 Inflammatory T-lymphocyte proliferation in morbid obesity K Van der Weerd, PM van Hagen, WA Dik, BS Schrijver, DH Schweitzer, AW Langerak, RM Kiewiet, MO Van Aken, JJM Van Dongen, AJ Van der Lelij, FJT Staal
P13 Elevated soluble Flt1 mediates an anti-angiogenic state in patients with ANCA-associated vasculitis
S Le Roux, R Pepper, A Dufay, M Néel, N Lamandé, M Rimbert, R Josien, M Hamidou, M Hourmant, HT Cook, B Charreau, E Larger, A Salama, F Fakhouri
P14 Functional relevance of a non-synonymous substitution in the CD5 gene (V471A) targeted for positive selection in East Asian populations
T Bielig, E Carnero-Montoro, L Bonet, J Engelken, M Arias, E Bosch, F Lozano
P15 Atopy in cutaneous and arthropatic psoriasis E Hajdarbegovic, AAA Westgeest, HB Thio
P16 Safety of treatment with biologics for psoriasis in daily practice: 5-year data
PPM Van Lümig, RJB Driessen, MAM Berends, JB Boezeman, PCM van de Kerkhof, EMGJ de Jong
P17 CCL4L polymorphisms and serum levels are associated with psoriasis severity
E Pedrosa, L Carretero-Iglesia, A Boada, R Colobran, I Pujol-Autonell,R Pujol-Borrell, C Ferrándiz, M Juan, JM Carrascosa
P18 Demonstration of novel innate immune cells in psoriasis R Mak, C Hundhausen, E Botti, U Laggner, K Grys, I Tosi, FO Nestle
P19 Expression of IL-1 family members upon stimulation with IL-17 differs in keratinocytes derived from psoriasis patients and healthy donors
P Muhr, J Zeitvogel, T Werfel, M Wittmann
P20 Mutations in the Fas gene found in Spanish ALPS (autoimmune lymphoproliferative syndrome) patients L Martínez-Martínez, C González-Santesteban, MV Rubiales, M Orta, I Badell, O de la Calle-Martin
P21 Discovery and validation of immunological biomarkers using an advanced flow cytometry platform
F Villanova, P Di Meglio, M Inokuma, VC Maino, FO Nestle
P22 Mast cells are major contributors to the pathophysiology of Graves’ Ophthalmopathy (GO)
L Van Steensel, D Paridaens, PM van Hagen, RWAM Kuijpers, WA Van den Bosch, HA Drexhage, H Hooijkaas, WA Dik
P23 Perivascular adipocytes and signaling through toll-like receptors: Role in the pathophysiology of atherosclerosis C Benaiges, X Garcia-Moll, E Mateus, C Muñoz, E Cantó, E Pérez, R Leta, E Moga, S Vidal, C Juarez
P24 Modulation of oxidative stress and TNFα secretion by peritoneal macrophages of arthritic rats fed with a flavonoid-enriched diet
S Ramos-Romero, FJ Pérez-Cano, C Ramírez-Santana, C Castellote, A Franch, M Castell
P25 Cocoa diet diminishes the anti-collagen humoral response in collagen-induced arthritis in rats
S Ramos-Romero, T Pérez-Berezo, FJ Pérez-Cano, C Castellote, M Castell, A Franch
P26 Toll-like receptor ligands regulate the migratory pattern of leukocytes
JC Nieto, E Cantó, MA Ortiz, C Juarez, S Vidal
P27 T cell repertoire analysis and comparison between different compartments in two MS patients
M Salou, L Michel, A Garcia, A Elong-Ngono, S Wiertlewski, JP Soulillou, S Brouard, DA Laplaud
P28 Mechanisms of action of Methylthioadenosine: Pathways implicated in neuroprotection in models of Multiple Sclerosis and other neurological diseases
P29 Natural Killer receptors distribution in Multiple Sclerosis JE Martinez-Rodriguez, M López-Botet
P30 Synovial fibroblast hyperplasia correlates with rheumatoid arthritis duration and activity and is partially reversed by anti-TNF therapy
E Izquierdo, JD Cañete, R Celis, MJ Del Rey, A Usategui, S Marsal, R Sanmartí, G Criado, JL Pablos
P31 Transcriptional response to hypoxia of normal and rheumatoid arthritis synovial fibroblasts
MJ Del Rey, E Izquierdo, A Usategui, E Gonzalo, FJ Blanco, F Acquadro, JL Pablos
P32 Monitoring of anti-TNF biological treatments
A Ruiz del Agua, D Pascual-Salcedo, A Balsa, I Ramos, L Novalbos, S Ramiro, A Martínez, L Simón, D Nagore
P33 Cytokine pattern in very early rheumatoid arthritis favours B cell activation and survival
RA Moura
P34 Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis R Cascão
P35 Caspase-1 is active since the early phase of rheumatoid arthritis
R Cascão, J Polido-Pereira, H Canhão, AM Rodrigues, M Navalho, H Raquel, AF Mourão, C Resende, JE Fonseca, LF Moita
P36 Spondyloarthropathy and rheumatoid arthritis: Two different diseases, a similar cytokine network
R Cascão
P37 Certolizumab pegol has a different profile from other anti-TNFs, including golimumab, in a variety of in vitro assays G Fossati, A Nesbitt
P38 Influence of variants of Fcg receptor IIA on the European league against rheumatism responses to anti-tumour necrosis factor alpha therapy in psoriatic arthritis
J Ramirez
P39 Identification of distinct polarized macrophage subsets in inflammatory arthritis
C Ambarus, S Krausz, J Hamann, MH Wenink, TRDJ Radstake, PP Tak, D Baeten
P40 Fecal S100A12 levels measured by a new ELISA are increased in ulcerative colitis (UC) and Crohn’s disease (CD) and correlates with intestinal damage
P Garnero, C Préaudat, S Vermeire
P41 Preferential expression of NF-κB-inducing kinase (NIK) in blood vessels of rheumatoid arthritis synovial tissue containing ectopic lymphoid neogenesis
AR Noort, KPM van Zoest, SW Tas, PP Tak
P42 IL-17A producing mast cells as therapeutic target in spondyloarthritis
N Yeremenko, I Gofita, T Noordenbos, PP Tak, J Canete, D Baeten
P43 TNF and IL-6 differentially regulate the production of DKK-1, a master regulator of bone remodelling, by fibroblast-like synoviocytes
N Yeremenko, R Bisoendial, J Zwerina, G Schett, PP Tak, D Baeten
P44 Descriptive study of patients with uveitis attended during one-year period - Diagnostic classification and treatment MV Hernández, V Ruiz-Esquide, JA Gomez-Puerta, J Ramirez, G Espinosa, A Adan, JD Cañete, R Sanmarti
P45 Interstitial lung disease in patients with scleroderma - Treatment with rituximab
A Muñoz, R Martínez, S Rodríguez, ML Velloso, JL Marenco
P46 Variants of PBEF predispose to systemic sclerosis and pulmonary arterial hypertension development JCA Broen
P47 Polymorphisms in the interleukin 4, interleukin 13 and corresponding receptor genes are not associated with Systemic Sclerosis and do not influence gene expression JCA Broen
P48 Systemic Sclerosis: Focus on lipid profile implications in pro-thrombotic disorder
C Ancuta, E Ancuta, C Belibou, R Chirieac
P49 Increased expression of A-kinase anchoring proteins in T cells from systemic lupus erythematosus patients
MJ Pérez-Lorenzo, M Galindo, AJ García-González, G Criado
P50 Role of TRAILR1 and TNFR1A polymorphisms in the
susceptibility and pharmacogenetics of rheumatoid arthritis and ankylosing spondylitis patients treated with infliximab MJ Morales-Lara, P Conesa-Zamora V Santaclara, D Torres-Moreno, F Pedrero, J Corral, M Perez-Guillermo, FJ Rodríguez-Martínez, E Soriano-Navarro
P51 Influence of a polymorphism IL1B gene in the response of
rheumatoid arthritis and ankylosing spondylitis patients treated with infliximab
MJ Morales-Lara, P Conesa-Zamora, V Santaclara, D Torres-Moreno, F Pedrero, J Moreno-Morales, V Cogolludo
P52 Painful myositis in the anti-synthetase syndrome with anti-PL12 antibodies
P Mehta, L Patel, F Roncaroli, MC Pickering, A Brand
P53 Toll-like receptor dependent autoantigens in animal models and humans in use to improve collagen induced arthritis B Marklein, Z Konthur, T Häupl, SR, MJ Shlomchik, G Steiner, H Lehrach, GR Burmester, F Apparailly, K Skriner
P54 Myeloid cell subsets dynamic during progression of mouse collagen-induced arthritis
J Presumey, C Jorgensen, G Courties, F Apparailly
P55 Anticitrullinated peptide antibodies (ACPA) in the serum of heavy smokers without arthritis - A differential role of associated pulmonary disease?
V Ruiz-Esquide, MJ Gómara, V Peinado, JA Gómez-Puerta, MV Hernández, JA Barberá, JD Cañete, I Haro, R Sanmartí
P56 BIK is a novel pro-apoptotic target gene for miR-125b in human monocytes
I Duroux-Richard
P57 National survey of patients with psoriatic arthritis in Spain: Disease activity, pharmacological therapy and impact on quality of life
JD Cañete, R Rodríguez, J Ramírez
P58 Cytokine expression in synovial tissue of psoriatic arthritis and its relationship with lymphoid neogenesis, disease activity and erosive disease: A longitudinal study
R Celis, J Ramírez, R Sanmartí, JL Pablos, JD Cañete
P59 Interleukin-1-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in human OA chondrocytes is associated with histone H3K4 methylation
N Chabane, N Zayed, J Martel-Pelletier, JP Pelletier, H Fahmi
P61 Prostaglandin D2 enhances interleukin -1beta- induced cyclooxygenase-2 expression in osteoarthritic cartilage N Zayed, FE El Mansouri, N Chabane, J Martel-Pelletier, JP Pelletier, H Fahmi
P62 Patients with non-relapsing ANCA-associated vasculitis have increased numbers of circulating IL-10 producing Th17 cells B Wilde, M Thewissen, P van Paassen, M Hilhorst, J Damoiseaux, O Witzke, JW Cohen Tervaert
P63 BioRePortAP, an electronic clinical record coupled with a database: An example of its use in a single centre
R Campanilho-Marques, J Polido Pereira, AM Rodrigues, F Ramos, MJ Saavedra, M Costa, JA Pereira da Silva, H Canhão, JE Fonseca
P64 Eight years of experience with biological treatment in juvenile idiopathic arthritis
AF Mourão
P65 Predictors of chronicity and the discriminative value of the new ACR/EULAR rheumatoid arthritis classification criteria in an untreated polyarthritis cohort with less than 6 weeks of disease duration
AF Mourão
P66 The effect of Rituximab treatment on T cells MA Ortiz
P67 Proteomic analysis of Systemic Sclerosis serum identifies the toll-like receptor agonists S100A8/A9 as a novel possible pathogenic marker
L van Bon, A Loof, H Wittkowski, W van Heerde, M Vonk, J Roth, W van den Berg, P van Lent, TRDJ Radstake
P68 Upregulation of inflammatory genes and downregulation of sclerostin are key elements for fracture healing
JE Fonseca
P69 Rituximab reduces anti-cardiolipin levels in patients with systemic lupus erythematosus
R Martínez-Pérez, A Muñoz-Jiménez, S Rodríguez-Montero, A Fernández-Nebro, L Carreño, JL Marenco
P70 Rituximab reduces the hospitalization in patients with systemic lupus erythematosus
R Martínez-Pérez, A Fernández-Nebro, M López-Lasanta, ML Velloso-Feijoo, A Muñoz-Jiménez, J López Longo, JL Marenco
P71 Rituximab is effective in the treatment of nephritis in lupus patients, refractory to conventional immunosuppressive therapy
R Martínez, A Muñoz, ML Velloso, S Rodríguez Montero, MA Belmonte-López, JL Marenco
P72 Analysis of biologic therapy in rheumatoid arthritis in a southern Spanish hospital population
J Uceda-Montañés, R Hernández-Sánchez, S Rodríguez-Montero, ML Velloso-Feijoo, A Muñoz-Jimenez, R Martínez-Perez, JL Marenco
P73 Mycophenolate mofetil use in refractory juvenile systemic lupus erythematosus
Author index
Aarntzen EHJG, I3 Adán AR, P44 Adema GJ, I3 Agarwal S, O1 Airò P, O1, P5, P46, P47 Alberch J, P28 Alcain G, P2 Aliprantis A, P47 Alizadeh BZ, O1, P2 Allanore Y, P47 Allroth A, I12 Almeida M, P73 Alsina M, P38 Ambarus C, P39 Amos CI, O1 Ancuta C, P48 Ancuta E, P48 Aouadi H, P7, P8 Aounallah-Skhiri H, P7, P8 Apparailly F, O3, P53, P54, P56 Aquadro F, P31
Arias, MT, P14 Arnett FC, O1, P46 Assassi S, O1 Ayed K, P7, P8
Baarsma SG, P1, P10 Badell I, P20
Baeten D, O6, P39, P42, P43 Balsa A, P32
Barberá JA, P55 Barclay ML, P2 Baron, M, O3 Bastiaans J, P1, P10 Baum, W, O8 Baumann U, I12 Becavin C, P3 Belibou C, P48
Belmonte-Lopez MA, P71 Ben Abdallah T, P7, P8 Ben Aleya W, P7 Ben Romdhane T, P7 Benaiges C, P23 Benecke A, P3 Berends MAM, P16 Beretta L, O1, P5, P46, P47 Bianchi E, O2, O5, P3 Bielig, T, P14 Binda, E, I1 Bisoendial R, P43 Blanco FJ, P31 Blanco F, P38 Boada A, P17 Boezeman JB, P16 Bonet, L, P14 Bosch E, P14 Bossini-Castillo L, P5 Botti, E, P18
Bottini N, P2 Boztug K, I12 Brand, A, P52
Broen, JCA, O1, O7, P5, P46, P47 Brouard S, P27
Brouwer C, P46 Bruggeman C, P11 Buderus S, I12 Burmester GR, P53, P56
Caetano-Lopes J, P68 Campanilho-Marques R, P63 Camps MT, P5
Cañete JD, P6, P30, P38, P42, P44, P55, P57, P58
Canhão H, P33, P34, P35, P36, P63, P64, P65, P68, P73 Cantagrel A, O3
Cantó, E, P4, P23, P26 Capela S, P65 Cardeña C, P2 Carnero-Montoro E, P14 Carrascosa JM, P17 Carreira P, O1, P5, P46, P47 Carreno L, P69
Carrtero-Iglesia L, P17
Cascão R, P33, P34, P35, P36, P65 Castell M, P24, P25
Castellote C, P24, P25 Castellvi I, P5 Celis R, P30, P58 Ceña, V, P28
Chabane N, P59, P60, P61 Charreau B, P13 Chee MM, O1, P5 Chirieac R, P48 Claes, K, P5
Coenen MJH, O1, O7, P5, P46, P47 Cof re M, O2, O5, P3
Cogolludo V, P51
Cohen Tervaert JW, P11, P62 Colobran R, P17
Conesa-Zamora P, P50, P51 Cook, HT, P13
Corominas H, P66 Corral J, P50 Costa M, P63 Courties G, O3, P54 Criado G, P30, P49 Crusius JB, P2 Cueto I, P2
Damoiseaux J, P62 Davignon JL, O3 de Baere E, O1 De Haas E, P1 de Jong EMGJ, P16 De Keyser F, O1, P5
de la Calle-Martín O, P20 De Langhe E, P5 De Vries IJM, I3 Del Rey MJ, P30, P31 Dennert R, P11 Denton CP, O1, P5, P46 Di Meglio P, P21 Di Penta A, P28 Diaz C, P66 Diaz-Gallo LM, O1, P2 Diaz-Torné C, P66 Dieli F, I1 Diestelhorst J, I12 Dieude P, P47
Dik WA, P1, P10, P12, P22 Dong, S, P3
Dontje W, O6 Dougados M, O2 Drexhage HA, P22 Driessen RJB, P16 Dufay, A, P13 Duroux-Richard I, P56
Egurbide MV, P5
El Mansouri FE, P59, P60, P61 Elong Ngono A, P27 Engelken J, P14 Errea, O, P28 Escriou V, O3 Espino-Paisán L, P2 Espinosa G, P5, P44
Fabre, S, P56 Fahmi H, P59, P60, P61 Fakhouri F, P13 Fernandes D, P68
Fernandez-Nebro A, P5, P6, P69, P70
Fernández-Sueiro JL, P38 Ferrnadiz C, P17 Figdor CF, I3 Filali A, P7 Flavell RA, I16
Fonollosa V, O1, P5, P46, P47 Fonseca C, O1, P5, P46 Fonseca JE, P33,P34, P35, P36,
P63, P64, P65, P68, P73 Fossati G, P37
Franch A, P24 Franch E, P25 Franco Salinas G, O6 Fransen K, P2
Galindo MA, P49 Gallego M, P5 Garcia A, P27
Garcia de la Peña P, O1, P5 García-González AJ, P49
García-Hernández FJ, O1, P5 Garcia-Moll X, P23 Garnero P, P40 Gearry RB, P2 Geli C, P66 Gertz, EM, I12
Geurts-van Bon L, O7, P46 Glocker EO, I12
Goi ta I, P42 Gómara JM, P55 Gomes Pedro J, P64 Gómez-García M, P2 Gomez-Gracia I, P5 Gómez-Puerta JA, P44, P55 González-Escribano MF, O1, P5 Gonzalez-Gay MA, O1, P5, P46,
P47
Gonzalez-Santesteban C, P20 Gonzalo E, P31
Gorgi, Y, P7 Gorlova O, O1 Gourh P, O1, P46 Graca L, P33, P34, P36 Grebe KM, P9 Gregersen PK, O1 Grimbacher B, I12 Gruen J, P56 Grützkau A, P56 Grys K, P18
Hajdarbegovic E, P15 Hamann J, P39 Hamidou M, P13 Haro I, P55 Harvey BP, O4 Hätscher N, I12 Häupl, T, P53, P56 Hayday AC, I1 Hayer, S, O8
Hernández MV, P44, P55 Hernandez-Sanchez R, P72 Hernanz JM, P6
Herrick A, O1, P5, P46, P47 Hesselstrand R, O1, P5, P46 Heymans S, P11
Hilhorst M, P62 Hinchclif M, O1 Hof mann-Vold AM, O1 Hooijkaas H, P10, P22 Hourmant M, P13 Houssiau F, O1, P5 Hundhausen C, P18
Hunzelmann N, O1, P5, P46, P47
Jorgensen C, O3, P54, P56 Josien R, P13
Juan M, P17
Juarez C, P4, P23, P26, P66 Julià , A, P6
Kamphuis LSJ, P10 Kaymakcalan Z, O4, P9 Kerschensteiner M, P28 Khazen D, P7 Kiener H, P46, P47 Kiewiet RM, P12 Kireva T, O8 Klein C, I12
Koeleman BPC, O1, P5 Koletzko S, I12 Konthur Z, P53 Konttinen YT, P68 Kotlarz D, I12 Krausz S, O6, P39 Kreipe H, I12 Kreuter A, O1, P5 Ksiaa-Cheikh Rouhou L, P8 Kuijpers RWAM, P1, P10, P22 Kwekkeboom DJ, P10 Kyburz D, P46
Lacher M, I12 Lafyatis R, I14, O7 Laggner U, P18 Laiz AM, P66 Lakhoua-Gorgi Y, P8 Lamandé N, P13 Lam-Tse WK, P10 Langerak AW, O7, P12 Laplaud DA, P27 Larger E, P13 Law H, O2 Le Roux S, P13 Lecellier CH, P56 Lee AT, O1 Lehrach H, P53 Lesterhuis WJ, I3 Leta R, P23 Lie BA, O1, P5 Llobet JM, P66 Loof A, P67 Lopes A, P68 Lopez I, P28 López R, P38 Lopez Longo J, P70 Lopez-Botet M, P29 Lopez-Lasanta M, P70 López-Nevot MA, P2 Lozano F, P14, P38 Lucas R, P68 Lunardi C, O1
Macieira CP, P64, P73 Madhok R, O1, P5 Maiella S, O5, P3 Maino VC, P21 Mak R, P18 Makhlouf M, P7 Mallat Z, I15
Marenco JL, P45, P69, P70, P71, P72
Marklein B, P53 Marques-Ponte RC, P73 Marsal S, P6, P30
Martel-Pelletier J, P59, P60, P61 Martin JM, O1
Martin J, O1, P2, P5, P46, P47 Martin K, P28
Martínez A, P32 Martínez R, P45, P71 Martinez-Martinez L, P20 Martinez-Pérez R, P69, P70, P72 Martinez-Rodriguez JE, P29 Mateus E, P23
Matri, S, P7 Matute C, P28 Mayes MD, O1, P46 McInnes IB, I10 Mehta P, P52 Mendoza JL, P2 Merriman TR, P2 Michel L, P27 Moga, E, P23 Moita, LF, P35 Moll C, P38 Monjardino T, P68 Monteiro J, P68 Montilla C, P38
Morales-Lara MJ, P50, P51 Moreno B, P28
Moreno-Morales J, P51 Mouelhi L, P7
Moura RA, P33, P34, P36, P65 Mourão AF, P33, P34, P35, P36,
P64, P65 Muhr, P, P19 Muñoz C, P23 Muñoz A, P45, P71
Munoz-Jiménez A, P69, P70, P72 Murugan D, I12
Nagore D, P32 Najjar, T, P7 Navalho M, P35 Navarrete N, P5 Néel M, P13 Nesbitt A, P37 Nestle FO, P18, P21 Niederer F, P46 Nieto A, P2 Nieto JC, P4 Nieto Sáchica JC, P26 Noordenbos T, P42 Noort, AR, P41 Nordin A, O1, P5 Novalbos L, P32 Noyan F, I12 Nustede R, I12
Ophof RA, O1 Orta M, P20
Ortego-Centeno N, O1, P5, P46, P47
Ortiz MA, P26, P66
Pablos JL, P30, P31, P58 Padykov L, P5 Padyukov L, O1 Palm Ø, P5 Panés J, P6 Parent J, P28 Paridaens D, P22 Pascual V, I2
Pascual-Salcedo D, P32 Patel L, P52
Peakman M, I4 Pedrero F, P50, P51 Pedrosa E, P17 Peinado V, P55 Pelletier JP, P59, P60, P61 Pepper R, P13
Pereira JP, P73
Pereira da Silva JA, P36, P63, P64, P65, P73
Pérez E, P23 Pérez-Berezo T, P25 Pérez-Cano FJ, P24, P25 Pérez-Guillermo M, P50 Pérez-Lorenzo MJ, P49 Perez-Ranz E, P66
Perpétuo IP, P33, P34, P36, P68 Perro, M, I12
Pers YM, P56 Pfeifer D, I12 Pickering MC, P52 Placek K, O5, P3 Plenge RM, I5
Polido-Pereira J, P33, P34, P35, P36, P63, P64, P65 Ponsioen CY, P2 Ponte, C, P73 Préaudat C, P40 Presumey J, O3, P54, P56 Pros A, P5
Pujol-Autonell I, P17 Pujol-Borrell R, P17 Punt CJA, I3
Radstake TRDJ, O1, O7, P5, P39, P46, P47, P67
Ramírez J, P38, P44, P57, P58 Ramírez-Santana C, P24 Ramiro S, P32
Ramos I, P32
Ramos FO, P63, P64, P73 Ramos-Romero S, P24, P25 Raquel H, P35
Reedquist K, O6 Resende C, P35, P65
Riemekasten G, O1, P5, P46, P47 Rimbert M, P13
Robert A, I1 Roberts RL, P2 Rodrigo L, P2
Rodrigues AM, P33, P34, P35, P36, P63, P73
Rodrigues A, P64, P65, P68 Rodriguez L, P5
Rodríguez R, P38, P57 Rodríguez S, P45
Rodriguez Montero S, P71, P72 Rodríguez-Martínez FJ, P50 Rodriguez-Montero S, P69 Rogge L, O2, O5, P3 Roman-Ivorra JA, P5 Roncaroli F, P52 Rosário HS, P33, P34, P36 Roth J, P67
Roumier M, O2 Rubiales MV, P20 Rueda B, O1, P5, P46, P47 Ruiz del Agua A, P32 Ruiz-Esquide V, P44, P55
Saavedra MJ, P63 Salama A, P13 Salfeld J, P9 Salliot C, O2 Salou, M, P27 Salzer U, I12
Sanmartí R, P30, P38, P44, P55, P58
Santaclara V, P50, P51 Santos MJ, P64 Sauer, M, I12 Sauerbrey A, I12 Schäf er AA, I12 Scherman D, O3 Schett G, O8, P43 Schrijver BS, P12 Schuerwegh AJ, O1, P5 Schweitzer DH, P12 Scorza R, O1, P5, P46, P47 Segal, AW, I12, I6 Serra, J, P28 Serrano M, I1 Sfar I, , P7, P8 Shah N, I12 Shiels P, O1, P5 Shlomchik MJ, P53 Simao C, P73
Simeon CP, O1, P5, P46, P47 Simón L, P32
Skriner K, P53 Smith V, O1, P5 Snapper SB, I12 Sonkoly E, I8 Soriano-Navarro E, P50 Soulillou JP, P27 Sousa E, P64
Souto-Carneiro MM, P33, P34, P36 Staal FJT, P12
Steiner G, P53 Stone, R, P73 Suárez B, P38 Sykora KW, I12
Tak PP, O6, P39, P41, P42, P43 Tan FK, O1
Tas SW, P41 Taxonera C, P2 Teixeira da Costa J, P64 Teruel M, O1
Tolosa C, P5 Tornero J, P6
Torres-Moreno D, P50, P51 Tortosa R, P6
Tosi I, P18
Uceda-Montanes J, P72 Urcelay E, P2
Usategui A, P30, P31
van Aken MO, P12 van Biezen P, P10 van Bilsen K, P1 van Bodegraven AA, P2 van Bon L, P67 van Daele PLA, P10 van de Kerkhof PCM, P16 van den Berg W, O3, P67 van den Bosch WA, P22 van der Burg M, I11
van der Lelij AJ, P12 van der Weerd K, P12 van Dongen JJM, P12
van Hagen PM, P1, P10, P12, P22 van Heerde W, P67
van Laar JAM, O1, P5, P10 Van Lent P, O3, P67 van Lümig PPM, P16 van Paassen P, P11, P62 van Riel PLCM, O1 van Rossum M, I3 van Sommeren S, P2 van Steensel L, P22 van ’t Slot R, O1 van Zoest KPM, P41 Vanthuyne M, O1 Varga, J, O1 Velloso ML, P45, P71 Velloso-Feijoo ML, P70, P72 Vermeire S, P40
Viana Queiroz M, P33, P34 Vicente E, P5
Vidal S, P4, P23, P26, P66 Vieira de Sousa E, P33, P34, P36 Villanova F, P21
Villoslada P, P28 Vinagre F, P64
Vonk, MC, O1, O7, P5, P46, P47, P67
Voskuyl AE, O1, P5
Wasmuth HE, I13 Weersma RK, P2 Weinmann P, P65 Wenink MH, P39 Werfel T, P19 Westgeest AAA, P15 Westhovens R, O1, P5 Wiertlewski S, P27 Wijmenga C, P2
Wilde, B, P62 Witte T, O1, P5 Wittkowski H, P67 Wittmann M, P19 Witzke O, P62 Woellner C, I12 Wolf s P, P11
Wolvers-Tettero ILM, O7 Worthington J, O1, P5, P46, P47
Yeremenko N, P42, P43 Ying J, O1
