MAML1 enhances the transcriptional activity of Runx2 and plays a role in bone development.

Runx1 (Runt-related transcription factor 1), a transcription factor that is essential for HSC emergence during the endothelial to hematopoietic cell fate conversion, but not

In the budding yeast Saccharomyces cerevisiae , resistance to arsenic is achieved through the activ- ation of the transcriptional regulator Yap8 [yeast AP-1-like transcription

methylation in promoter regions of osteoblastic- related genes (i.e. RUNX2, OSX, DLX5 and BSP ) in relation to osteoblastic differentiation potential. in

On the one hand, SUMOylation of Sox2 inhibits its transcriptional activity and represses Nanog transcription, while SUMOylation also disturbs the protein- protein interaction

Sox9 as a master transcription factor for chondrogenesis also delayed BMP2 induced bone formation of MSCs, and endochondral ossification through repress Runx2 expression, and thus

We found that Med19 activity is required in the Drosophila haltere disc for transcriptional activation of CG13222 / edge and bab2 , but is dispensable for Ubx-mediated repression

Given that intermolecular disulfide bond formation occurs upon HOCl, NH2Cl, and H2O2 treatment both in vitro and in vivo but only HOCl-stressed cells show HypT- dependent

Here we report that Mixl1 interacts physically and functionally with the T-box protein Brachyury and related members of the T-box family of transcription factors.. Transcriptional