Mucosa-associated lymphoid tissue lymphoma of the lachrymal gland: A case report

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BIBLID: 0370-8179, 133(2005) 5-6 p. 272-275 UDC: 617.764.1-006-08:615.849

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FIGURE 2. A computerized tomograph of the head revealed a tumour in front of the right eyeball in the right lachrymal gland, 26 mm in di-ameter.

SLIKA 4._{ƲǢǠǖǠǢǤǥǞǠǢǣǜǚǧǼǗǝǚǹǑǥǗǡǚǤǗǝǘǝǗǙǖǑǟǚǧǑǨǚǟǥǣǑǚ} ǚǙǓǠǖǟǚǧǜǑǟǑǝǑǥǠǒǝǚǜǥǝǚǞǦǠǗǡǚǤǗǝǟǚǧǝǗǙǚǹǑ HEǥǓǗǝǚǩǑǻǗ v

FIGURE 4. Penetration of tumour cells into the epithelium of acinus glands and exit channels in the form of lymphoepithelial lesions (HE, magniication ×40).

SLIKA 3.ƵǥǞǠǢǣǜǚǚǟǦǚǝǤǢǑǤǣǥǩǚǟǚǝǚǞǑǝǚǝǚǞǦǠǨǚǤǚǡǠǞǗ ǪǑǟǚǣǑǞǠǟǠǨǚǤǠǚǖǟǚǞBǼǗǝǚǹǑǞǑǼǗǝǚǹǗǣǝǚǩǟǗǨǗǟǤǢǠǨǚǤǚǞǑ ǚǡǝǑǙǞǑǼǗǝǚǹǑǞǑ HEǥǓǗǝǚǩǑǻǗv

FIGURE 3. Tumour iniltration was caused by small lymphocytes mixed with monocytoid B-cells, similar to centrocytes and plasma cells (HE, magniication ×20).

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Don-frid M. Primary intraocular marginal zone B-cell (MALT) lym-phoma. Eur J Haematol 1997; 58:1-2.

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ABSTRACT

Mucosa-associated lymphoid tissue (MALT) lymphoma has drawn attention in the last twenty years due to its pathological and clinical characteristics. It is a question of B-cell neoplasm with extranodal origin, and with invariable prolonged locali-sation, indicating indolent malignancy. It is believed that this type of lymphoproliferative neoplasm is triggered by chron-ic antigenchron-ic stimulation. This is supported by the observation that this type of extranodal lymphoma is frequently found in regions affected by chronic inflammation, such as mucosa of the stomach, the respiratory tract, as well as of the salivary and the thyroid glands. It is not common in the breasts, liver, kidneys, and gallbladder. Primary orbital lymphomas account for 5-14% of all extranodal lymphomas. The most commonly involved orbital tissue structures are: conjunctiva, the eyelids, and retrobulbar tissue, while the development of the disease in the lachrymal gland is extremely rare. No wonder that the

lit-erature on the presentation, treatment modalities, and recom-mendations for the monitoring of MALT lymphoma of the lach-rymal gland is so scarce. Given the aforementioned facts, the case report of a patient with primary localisation of MALT lym-phoma of the lachrymal gland was considered intriguing; ini-tially, the patient was successfully treated by surgical interven-tion followed by radiainterven-tion therapy (TD 30 Gy).

Key words: MALT lymphoma; lachrymal gland; radiation therapy

Ružica NEDELJKOV-JANČIĆ Institut za hematologiju Klinički centar Srbije

Dr Koste Todorovića 2, 11000 Beograd Tel: 011 361 7777, lokal 3723

E-mail: ruzicajn@yahoo.com

MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA

OF THE LACHRYMAL GLAND – A CASE REPORT

Ružica NEDELJKOV-JANČIĆ, Biljana MIHALJEVIĆ, Milena BAKRAČ, Milan PETROVIĆ Institute of Haematology, Clinical Centre of Serbia, Belgrade