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Thrombospondin1 deficiency reduces obesity-associated inflammation and improves insulin sensitivity in a diet-induced obese mouse model.

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Academic year: 2017

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Table 1. Sequences of primers used in the study.
Figure 1. TSP1 deficiency had no effect on obesity development in a high fat diet induced obese mouse model
Figure 2. Obese TSP1-/- mice had improved glucose tolerance and insulin sensitivity. Male TSP1-/- mice and wild type littermate controls were fed LF or HF diet for 16 weeks
Figure 5. Obesity induced systemic inflammation was reduced in TSP1-/- mice. Plasma IL-6, TNF-a, and PAI-1 levels were measured as described in Material and Methods section
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