Activation of Cre recombinase alone can induce complete tumor regression.

Antiapoptotic members of the Bcl-2 family (B cell CLL/lymphoma 2), that belong to the intrinsic route of the activation of caspases, such as Bcl-xL (extra-large B-cell lymphoma)

RESULTS: Prima-1 was able to reactivate p53 function in the T24 (p53 mt) bladder cancer cell line and promote apoptosis via the induction of Bax and Puma expression, activation of

For the irst-line treatment of follicular lymphoma, R-CHOP (rituximab combined with CHOP) compared to CHOP alone as the irst-line treatment for follicular lymphoma, the

Histopathological testing of the tumor confirms the diagnosis of lymphoma and immunophenotyping differentiates primary nasal lymphoma - derived from T-cells - from B-cell

Hence, in this study, we sought to clarify the following issues: (1) whether PRC alone can be used as an isolated growth medium to induce osteogenic differentiation of hMSCs,

By crossing the Osx-Cre mouse with the R26-mT/mG reporter line and analyzing the progenies at two months of age, we find that Osx-Cre targets not only osteoblasts, osteocytes

Using the Mx1-Cre;mT/mG reporter mouse model, we found that the calvarial cells exhibited minimal background Mx1-Cre activity prior to Cre activation by IFN α treatment as compared

Figure 2. Pitx3-Cre driven expression of eYfp is detected in all mdDA neurons in the adult murine brain. A) Expression of eYfp in the lens and areas of the telencephalon