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Novel Penicillin Analogues as Potential Antimicrobial Agents; Design, Synthesis and Docking Studies.

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Academic year: 2017

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Fig 1. Synthesis of Penicillin derivatives (4a-h).
Fig 2. Chemical structure and three dimensional view of compounds 4c and 4e with highlighted green show the main penicillin nucleus and red show the designed moiety to increase the bioactivity.
Table 1. Antibacterial activity result of penicillin derivatives (4a-h).
Table 2. Hydrogen bonding between penicillin derivatives (4a-h) and receptor.
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