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Conformational Sampling and Binding Site Assessment of Suppression of Tumorigenicity 2 Ectodomain.

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Fig 1. Models of ST2 fitted to the SAXS data using MultiFoXS and MES algorithms. (A) Fitting curves and residual plots of the 1-state and 3-state models based on MultiFoXS and MES
Fig 2. Projection of IL-1R1/2, ST2 crystal structures and ST2 ECD models to the first three principal components subspace
Fig 3. Projection of ST2 ECD conformations obtained from a total of 80 ns aMD simulations to the PC subspace
Fig 4. Projection of ST2 ECD conformations obtained from aMD simulations and the mean shift cluster analysis
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