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The role played efflux systems on the resistance to antibiotics

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Academic year: 2021

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Figure  1.  Outer  membrane  permeability  barrier  in  Gram-negative  bacteria.  Drugs  penetrate across the outer membrane, the more hydrophilic passing through the narrow porin channel with  difficulty,  and  the  more  lipophilic  penetrating  through
Figure  2.  Diagrammatic  representation  of  the  membrane  topology  of  single-  or  multi-component proton-driven pumps in Gram-negative bacteria
Figure  3.  Schematic  illustration  of  the  main  types  of  bacterial  drug  efflux  pumps
Figure  4.  Structural  model  for  the  12-transmembrane  segment  (A)  and  the  14-  transmembrane  segment  (B)  drug  efflux  pumps  of  the  MFS
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