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DOI:

10.1590/0004-282X20150186

IMAGES IN NEUROLOGY

Transient ischemic attack caused by cerebral

ergotism

Ataque isquêmico transitório causado por ergotismo cerebral

Gustavo Andrés Gaye-Saavedra, Federico Preve, Silvana Albisu, Mariana Legnani

Association of protease inhibitors and ergotamine

caus-ing systemic ergotism is well established

1,2,3

. Cerebral

ergot-ism is poorly reported

4,5

. We describe the case of an HIV

positive 49 yo man under protease inhibitors (ritonavir)

pre-senting with total reversible left hemiparesis after the intake

of 3 g of ergotamine. After 20 minutes he was

spontaneous-ly asymptomatic. TIA was diagnosed. Parenchymal MRI was

normal, cervical doppler ultrasound showed symmetric

nar-rowing in both internal carotid arteries, causes of cardiac

em-bolism were properly excluded. Angio Magnetic Resonance

Imaging (Figures 1 and 2) was performed in acute stage and

evolution, as well as cerebral angiography, leading to the

di-agnosis of cerebral ergotism. Between both MRI showed, only

aspirin 325 mg and bed rest was indicated.

Universidad de la República, Facultad de Medicina, Hospital de Clínicas, Unidad AVC, Montevideo, Uruguay.

Correspondence: Gustavo Andrés Gaye Saavedra; Hospital de Clínicas, Facultad de Medicina, Universidad de la República; Av Italia, s/n; 11600; Montevideo, Uruguay; E-mail: gayeandres@hotmail.com

Conflict of interest: There is no conlict of interest to declare.

Received 30 July 2015; Received in inal form 22 September 2015; Accepted 14 October 2015.

References

1. Finn BC, Vadalá S, Meraldi A, Bruetman JE, Martínez JV, Young P. [Ergotism and HIV]. Medicina (B Aires). 2013;73(4):346-8. Spanish. 2. Acle S, Roca F, Vacarezza M, Álvarez Rocha A. [Ergotism secondary

to ergotamine-ritonavir association: Report of three cases]. Rev Med Chil. 2011;139(12):1597-600. Spanish. doi:10.4067/S0034-98872011001200010

3. Ayarragaray JE. Ergotism: a change of persepective. Ann Vasc Surg. 2014;28(1):265-8. doi:10.1016/j.avsg.2013.02.005

4. Spiegel M, Schmidauer C, Kampl A, Sarcletti M, Poewe W. Cerebral ergotism under treatment with ergotamine and ritonavir. Neurology. 2001;57(4):743-4.

5. Langer B, Bechara MJ, Wolosker N, Sitrangulo Júnior C, Marino JC. [Transient cerebral ischemic attack and amaurosis fugax caused by carotid ergotism]. Rev Paul Med. 1991;109(2):91-2. Portuguese.

Figure 1.

Angio MRI showing progressive and symmetrical

narrowing in both internal carotid arteries after the origin with

minimum intracranial illing. T1 fat suppression secuence did

not show a dissection pattern.

Figure 2.

Control MRI at 7 days: Normal illing of both internal

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VI

ERRATUM

DOI:

10.1590/0004-282X20150186errata

Erratum

Arquivos de Neuro-Psiquiatria. ahead of print Epub 24-Nov-2015.

Imagem

Figure 2. Control MRI at 7 days: Normal illing of both internal  carotid arteries is seen

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