Positional bias of MHC class I restricted T-cell epitopes in viral antigens is likely due to a bias in conservation.

In this study, HLA transgenic mice, HLA-A2, -A24, -B7, -DR2, -DR3, and DR4, were immunized with 196 overlapping H1N1 peptides of the A/New York/348/2003 strain that contained the

The SAR analysis was facilitated by the linear PLS-regression model correlating the presence of a specific amino acid in p260 and p263 to the affinity of the peptides for A q

negativo, mantienen similar fondo semántico, se puede utilizar la definición antes mencionada para definir también al bias positivo y bias negativo. Las definiciones

The sequence of events used was: (1) specifica- tion of the trait and effects of the favorable genes, with insertion of the degree of dominance (the same for each gene),

The effect of mAb to MHC I and II molecules on the lymphocyte proliferative response to leishmania antigen in patients with tegumentary leishmaniasis is shown in Figure 1.. Although

Two authors (AHNB, HSM) extracted the data from each study and entered them into a table with the following information: sample (age group, sex, clinical

We present a structure-based method for predicting class II epitopes that combines molecular mechanics docking of a fully flexible peptide into the MHC binding cleft followed by

In particular, the prediction performance of GPS-MBA 1.0 is much poorer in terms of the MHC class I epitopes, such that only one and three epitopes were predicted as I-A g7 and