Prp4 Kinase Grants the License to Splice: Control of Weak Splice Sites during Spliceosome Activation.

Furthermore, this interaction is regulated by MEK kinase-dependent phosphorylation of STMN1, which has an important role in cell proliferation, differentiation, migration

To investigate the impact of SRSF5 regulated expression on pre-mRNA splicing in erythroid cells, we undertook a functional analysis on alternative splicing of the endogenous

Expression analysis of the splice variants revealed that one splice form (AgAQP1A) is specifically expressed in adult female ovaries, while the other (AgAQP1B) is

Physiological concentrations of cytokine in the picomolar range were sufficient for activating the protein kinase activity of PI3K leading to Ser585 phosphorylation and hemopoietic

In contrast to this model, the results of the present study with intact cells and tissues indicate that neither cGKI a nor cGKI b is phosphorylated in its N-terminal region in vivo ,

To comprehensively identify factors required for pericentric heterochromatin assembly, we performed a screen of the fission yeast haploid deletion library for mutants that

The mecha- nism of splice site selection in constitutive and alterna- tive splicing are closely connected, since components of the splicing machinery, essential for

Furthermore, the Srrm4- dependent splicing of Rest had been shown to affect the expression of numerous Rest-regulated genes in Neuro2A cells [37], and our analysis of the MJAY