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Rev. Assoc. Med. Bras. vol.57 número6 en v57n6a07

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ACCREDITATION

615

Rev Assoc Med Bras 2011; 57(6):615

1. Comparison with oral administration showed that the action of inhaled BDL is faster and has fewer side efects (Alternative A).

2. he inhalation route is preferably recommended for the use of β-adrenergic in asthma attack (Alternative C).

3. here is similar eicacy between the use of high-dose inhaled corticosteroids and systemic corticosteroids (Alternative A).

4. Aminophylline has a narrow therapeutic safety margin and may cause poisoning and side efects (Alternative D).

5. Continuous treatment with corticosteroids is associated with decreased rates of hospitalization (Alternative B).

RESPONSESTO CLINICALSCENARIO: UPDATEON CHILDHOODASTHMA: DRUG TREATMENT

[PUBLISHEDIN RAMB 2011, 57(5)]

Update on gastroesophageal reflux disease (GERD): diagnosis

ALOISIO CARVALHAES, JAIME NATAN EISIG, WANDERLEY MARQUES BERNARDO

1. Should patients with heartburn and endoscopic examination without upper esophageal erosions be submitted to esophageal pH-metry to conirm the diagnosis?

a. Abnormal pH-metry deines the diagnosis with 50% certainty. b. Normal pH-metry excludes the diagnosis with 95% certainty. c. In these patients, pH-metry has a sensitivity of 65%.

d. In these patients, pH-metry has a speciicity of 100%.

2. Is the wireless capsule for esophageal pH monitoring better than conventional esophageal pH-metry to diagnose GERD?

a. Although the capsule is less invasive, the level of discomfort is the same. b. he capsule records a higher number of relux episodes.

c. Interference in daily life is higher with the capsule.

d. he number of diagnoses is similar between the two procedures.

3. Should all patients with atypical manifestation undergo esophageal pH-metry?

a. he prevalence of GERD in patients with atypical symptoms is 63.4%. b. In patients with chronic cough, most symptoms depend on the relux. c. Acid relux is associated with more atypical symptoms.

d. Globus sensation can only be investigated with dual-channel pH-metry.

4. Should patients with refractory GERD undergo esophageal biopsy?

a. he diameter of intercellular spaces in GERD is half the normal.

b. he recovery of the intercellular space is similar to the recovery of symptoms. c. Sensitivity and speciicity of biopsy are 98% and 99%, respectively.

d. Biopsy allows the diagnosis of GERD non-responsive to treatment.

5. Should patients with asthma be investigated for GERD?

a. Pantoprazole 40 mg twice daily for 1 week improves asthma symptoms. b. he use of omeprazole 20 mg twice daily does not afect asthma symptoms.

c. In asthmatic patients with relux symptoms, normal pH-metry predicts therapeutic unresponsiveness. d. Symptoms of relux in pulmonary ibrosis are less frequent than a positive-test result for GERD.

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