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Insights into cytochrome bc

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Academic year: 2019

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Fig. 1: chemical structures of atovaquone analogues and their experi- experi-mental pIC 50  values for antimalarial activity.
Fig. 3 shows in detail the structural elements from  the CYB subunit involved in the constitution of the Q o site in cytochrome bc 1
Fig. 3: characterisation of Q o  site in Plasmodium falciparum bc 1 . (A) Alignment of cytochrome b sequences from Plasmodium sp causing human  malaria and homologous proteins in yeast, cow, chicken and human showing structural elements composing the Q o
Fig. 4: binding mode analysis for atovaquone analogues in the Q o  site in Plasmodium falciparum bc 1
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