Candidate vaccine
Comparative evaluation of phenol and thimerosal as preservatives for a candidate vaccine against American cutaneous leishmaniasis
... a candidate vaccine, preserved by phenol, to induce immunity against ...the candidate vaccine group, but this evidence of immunogenicity induced by the candidate vaccine was not ...
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A glycoprotein E gene-deleted bovine herpesvirus 1 as a candidate vaccine strain
... a candidate vaccine strain ...no vaccine containing gene-deleted BoHV-1 or BoHV-5 is yet available in ...a vaccine strain; 3) it is highly immunogenic in cattle; 4) genital and respiratory ...
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Differing patterns of selection and geospatial genetic diversity within two leading Plasmodium vivax candidate vaccine antigens.
... for vaccine design. The malaria vaccine field is just beginning to unravel how antigenic diversity within a single parasite population can reduce vaccine efficacy ...vivax vaccine – antigenic ...
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Comparative evaluation of phenol and thimerosal as preservatives for a candidate vaccine against American cutaneous leishmaniasis
... the candidate vaccines to induce persistent pro- tection in C57BL/10 mice against a challenge with in- fective ...each candidate vaccine according to the schedule described in the materials and ...
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Generation and Characterization of Live Attenuated Influenza A(H7N9) Candidate Vaccine Virus Based on Russian Donor of Attenuation.
... A(H7N9) candidate vaccine viruses by reverse genetics The mutations present in the HA of a vaccine candidate seed virus could potentially affect its antigenicity and effectiveness [39, ...the ...
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StreptInCor: a candidate vaccine epitope against S. pyogenes infections induces protection in outbred mice.
... on vaccine development for ...terminus-based vaccine was first developed using the 26 most frequent GAS strains in the ...30-valent vaccine construction that was immunogenic in rabbits, inducing ...
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Safety and immunogenicity of a glycoprotein E gene-deleted bovine herpesvirus 1 strain as a candidate vaccine strain
... BoHV-1 vaccine accompanied by a reliable vaccination program would probably confer protection to both viruses in areas where they ...this vaccine against BoHV-5 challenge to generate confirmatory data that ...
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Hepatitis B Vaccines and HPV Vaccines Have Been Hailed as Major Public Health Achievements in Preventing Cancer--Could a Schistosomiasis Vaccine be the Third?
... ing candidate vaccine suggest that it may feature both pre- and post-exposure efficacy for intes- tinal and urogenital schistosomiasis ...the vaccine in young children should be a ...HPV ...
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Protection against multiple influenza A virus strains induced by candidate recombinant vaccine based on heterologous M2e peptides linked to flagellin.
... In this study, we investigated the possibility of developing an M2e-based candidate vaccine that is capable of forming protective immune response simultaneously against human and avian influenza A viruses. ...
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Mucosal vaccination with recombinant adenovirus encoding nucleoprotein provides potent protection against influenza virus infection.
... mucosal vaccine candidate that could offer broad-range cross-protection against multiple strains of influenza ...our candidate vaccine virus via two different, intranasal and sublingual, ...
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A Library of Plasmodium vivax Recombinant Merozoite Proteins Reveals New Vaccine Candidates and Protein-Protein Interactions.
... more vaccine can- didates, we expressed the entire ectodomains of 37 proteins that are predicted to be involved in ...of candidate vaccine ...
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Production of a subunit vaccine candidate against porcine post-weaning diarrhea in high-biomass transplastomic tobacco.
... Enterotoxigenic Escherichia coli (ETEC) strains that produce long proteinaceous appendages on their surfaces, called F4 fimbriae (F4+ ETEC), are the key culprit for Post-Weaning Diarrhea (PWD) among newly weaned piglets ...
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A novel live-attenuated vaccine candidate for mayaro Fever.
... This vaccine candidate was also highly immunogenic, inducing high levels of neutralizing antibody titers in both adult CD1 and A129 mice at 28 days ...
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Evaluation of Leishmania donovani protein disulfide isomerase as a potential immunogenic protein/vaccine candidate against visceral Leishmaniasis.
... Encouraged with these observations we further evaluated the prophylactic potential of LdPDI as a plasmid DNA vaccine to L. donovani challenges. It has been shown in a variety of experimental models of infection ...
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Recombinant tegumental protein Shistosoma japonicum very lowdensity lipoprotein binding protein as a vaccine candidate against Schistosoma japonicum
... a vaccine for schistosomiasis. Develop- ment of a vaccine against the disease remains a worth- while and desirable goal in view of controlling the trans- mission of schistosomiasis (Chitsulo et ...
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Structure of the malaria antigen AMA1 in complex with a growth-inhibitory antibody.
... One such antigen that shows promise as a vaccine candidate is apical membrane antigen 1 (AMA1). AMA1 is a type I integral membrane protein with a 55–amino acid cytoplasmic segment and a 550–amino acid ...
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High resolution human leukocyte antigen class I allele frequencies and HIV-1 infection associations in Chinese Han and Uyghur cohorts.
... In our Uyghur cohort, the frequency of HLA-B*5101 was significantly higher in the HIV-1 negative group. A novel HIV-1 vaccine candidate designed for B*5101 positive individuals protected mice against ...
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Characterization of a new malaria vaccine candidate against Plasmodium vivax using genetically modified rodent Plasmodium parasites
... With the advancements in the genetic engineering field, the increased knowledge of the Plasmodium genome and the possibility of its manipulation, it was demonstrated that sporozoites lacking certain stage-specific genes ...
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Rev. Saúde Pública vol.20 número1
... of measles vaccine storage montly, temperature.. Leia-se: of measles vaccine storage, mostly temperature..[r] ...
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A candidate HIV/AIDS vaccine (MVA-B) lacking vaccinia virus gene C6L enhances memory HIV-1-specific T-cell responses.
... HIV-1 vaccine candidate, termed MVA-B DC6L, which contains a deletion in the vector backbone of MVA-B of the VACV C6L ...the candidate HIV/AIDS vaccine vector MVA-B could improve the humoral ...
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