Cell injury
Nitrative Stress Participates in Endothelial Progenitor Cell Injury in Hyperhomocysteinemia.
... endothelial injury in hyperhomo- cysteinemia (HHcy), thirty healthy adult female Wistar rats were randomly divided into three groups: control, hyperhomocysteinemia model, and hyperhomocysteinemia with FeTMPyP ...
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Mononuclear Phagocyte-Derived Microparticulate Caspase-1 Induces Pulmonary Vascular Endothelial Cell Injury.
... endothelial cell apoptosis and injury occurs throughout all stages of acute lung injury (ALI/ARDS) and impacts disease ...endothelial injury has traditionally been focused on the role of ...
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Disturbance of copper homeostasis is a mechanism for homocysteine-induced vascular endothelial cell injury.
... The data obtained from this study showed that the exposure of HUVECs to Hcy at clinically relevant concentrations caused a concentration-dependent endothelial cell injury. Treatment with Hcy resulted in an ...
9
Renal Impairment with Sublethal Tubular Cell Injury in a Chronic Liver Disease Mouse Model.
... Renal injury markers, renal histology (including immunohistochemistry for tubular injury markers and transmission electron microscopy), autophagy, and oxidative stress were studied longitudinally in DDC- ...
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Regulation of S1P receptors and sphingosine kinases expression in acute pulmonary endothelial cell injury
... that the activity of SphK1 and the dynamic concentration balance of SphK1/S1P axis, are necessary for the modulation of inflammatory signals and are related to the regulation of innate, adaptive and other immune cells. ...
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Glomerular endothelial cell injury and damage precedes that of podocytes in adriamycin-induced nephropathy.
... One of the most important mediators released by the endothelium is NO. NO acts as a potent vasodilator, and also inhibits inflammation, growth of vascular smooth muscle and aggregation of platelets [20–23]. Dysregulation ...
12
Long non-coding RNA HOTAIR promotes UVB-induced apoptosis and in flammatory injury by up-regulation of PKR in keratinocytes
... keratinocyte injury is ...inflammatory injury in human keratinocytes (HaCaT ...IL-6. Cell viability was measured using trypan blue exclusion method and cell apoptosis using flow cytometry and ...
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Facilitative interaction between angiotensin II and oxidised LDL in cultured human coronary artery endothelial cells
... and LOX-1 expression are responsible for exten- sive cell injury. This interaction (cross-talk) sug- gests a critically important role for the RAAS and abnormal lipid levels in blood. Indeed, several ...
7
Effect of methamphetamine on the microglial damage: role of potassium channel Kv1.3.
... Meth-induced cell injury was ameliorated by MgTx, and recent evidence indicated that activated microglia express higher levels of Kv channels [19], then we next explored whether this effect could be related ...
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Environmental interaction, additive and non-additive genetic variability is involved in the expression of tissue and whole-plant heat tolerance in upland cotton (
... Tissue tolerance to heat stress was assessed by the in vitro cellular membrane thermostability (CMT) assay which provides a measure of relative cell injury (RCI), a low RCI value indicating higher CMT and ...
8
Clinics vol.68 número7
... of cell injury and has been associated with ischemic events in the intestine (25), while interleukin-1 beta is considered a marker of acute inflammation, resulting in the activation of macrophages during ...
5
Influence of Two Various Durations of Resistance Exercise on Oxidative Stress in the Male Rat’s Hearts
... reduce cell injury resultant from oxidative stress induced by ...and cell injury level in heart depend on duration of exercise may be due to reducing of the basic deteriorative reactions ...
5
Int. braz j urol. vol.36 número3
... epithelial cell injury akin to stent movement, as ureteric stents are associated with urinary tract complications that can signiicantly add to patient ...mechanical injury to the urinary ...
1
Clinics vol.70 número5
... proliferating cells at 60 min after reperfusion, as demon- strated by the increased expression of Ki-67. Thus, the IEGs c-fos and c-jun together may be responsible for cell prolifera- tion and apoptosis. The major ...
7
The jagged-2/notch-1/hes-1 pathway is involved in intestinal epithelium regeneration after intestinal ischemia-reperfusion injury.
... To inhibit the Notch signaling pathway, an in vitro transfection to silence Jagged-2 and Hes-1 expression was performed. siRNA were chemically synthesized by Ribobio (Guangzhou, China). The sequences of the siRNAs ...
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Autophagy: A Novel Therapeutic Target for Diabetic Nephropathy
... he evolution of autophagy has enabled it to be activated un- der nutrient-depleted conditions, to overcome long-term pe- riods of starvation. For the past several decades, many investi- gators have tried to identify ...
10
T cell IFN-γ suppression following alcohol and burn injury is independent of miRNA155.
... T cell activation and differentiation into various subsets is further controlled by a class of small non- coding RNAs referred to as microRNAs (miRNAs) ...immune cell development and function ...T ...
8
Leptin Downregulates LPS-Induced Lung Injury: Role of Corticosterone and Insulin
... Lung cells were lysed in RIPA buffer, run on 10% SDS-polyacrylamide electrophoresis gels and transferred onto nitrocellulose membranes (Hybond C Extra, Amersham Biosciences, Little Chalfont, UK). The membranes were ...
12
Temporal network based analysis of cell specific vein graft transcriptome defines key pathways and hub genes in implantation injury.
... implantation injury, based on endpoint molecular signals involved in lesion ...both cell types, three of which spanned all time-points, namely the IL-8, IL-6 and dendritic cell maturation ...
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PABLO HERTHEL DE CARVALHO TRANSPLANTE ALOGÊNICO DE CÉLULAS-TRONCO MESENQUIMAIS INDUZ ALTERAÇÃO DO PERFIL DE CITOCINAS PRÓ E ANTINFLAMATÓRIAS E DE FATORES NEUROTRÓFICOS NO
... Acredita-se que a substituição de células neurais pelas CTM não seja a principal contribuição, mas sim a modulação da resposta inflamatória e a ação de fatores de crescimento, que podem estimular as células-tronco ...
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