Cysteine proteases
Giardia duodenalis Surface Cysteine Proteases Induce Cleavage of the Intestinal Epithelial Cytoskeletal Protein Villin via Myosin Light Chain Kinase.
... the cysteine pro- teases into the cells from the ...CA cysteine proteases, some ...CA cysteine proteases induce vil- lin degradation and redistribution within IECs and that this effect, ...
28
Hemoglobin cleavage site-specificity of the Plasmodium falciparum cysteine proteases falcipain-2 and falcipain-3.
... aspartic proteases from two parasites that hydrolyze this substrate, schistosome worms that degrade hemoglobin extracellularly [44] and malaria parasites that degrade hemoglobin in an intracellular acidic ...
10
Kaurene diterpene induces apoptosis in U87 human malignant glioblastoma cells by suppression of anti-apoptotic signals and activation of cysteine proteases
... intracellular cysteine proteases with specificity for aspartic acid ...these cysteine proteases, referred to as ‘‘initiator’’ and ‘‘effector’’ caspases, play important roles in the apoptotic ...
8
Expression, characterization, and cellular localization of knowpains, papain-like cysteine proteases of the Plasmodium knowlesi malaria parasite.
... papain-like cysteine proteases. The identified proteases were termed knowpains and designated as knowpain-1 (KP1), knowpain-2 (KP2), knowpain-3 (KP3), and knowpain-4 ...papain-like proteases, ...
14
Structure-activity relationships of hypervalent organochalcogenanes as inhibitors of cysteine cathepsins V and S
... in cysteine proteases inhibition were ...towards cysteine cathepsins V and ...against cysteine cathepsins V and ...and cysteine cathepsins was proposed after the comparison of the ...
6
Influência de inibidores proteicos e não-proteicos de proteases digestivas e caracterização bioquímico-cinética de cisteíno-proteases parcialmente purificadas de Anticarsia gemmatalis
... intestinal proteases to knowledge of their catalytic ...kinetically cysteine proteases produced in the intestinal tract of caterpillar Anticarsia ...gemmatalis. Cysteine proteases of ...
69
Biochemical Aspects of a Serine Protease from Caesalpinia echinata Lam. (Brazilwood) Seeds: A Potential Tool to Access the Mobilization of Seed Storage Proteins
... different proteases in the mobilization and cleavage of seed storage proteins upon seed imbibition and germination, which is an essential step in the establishment of the seedling ...other proteases such as ...
9
Partial Purification of Milk Clotting Protease
... a cysteine protease (table ...aspartic proteases, mainly animal and microbial source, but protease from the vegetable can be used too, such as seric proteases such as cucumisin (EC ...3.4.21.25), ...
9
Purificação e caracterização parciais de serino e cisteíno proteases de Sitophilus zeamais (Coleoptera: Curculionidae)
... and cysteine proteases of a susceptible and two resistant strain (one with a cost associated with resistance and other without cost) of the maize weevil Sitophilus zeamais were partially purified using an ...
79
Host cell invasion by Trypanosoma cruzi is potentiated by activation of bradykinin B-2 receptors
... the cysteine proteases from wild- type (WT) Dm28c TCTs or TCT-cz2 was assessed by mixing 2 ml of the Triton X-100 lysates (1 mg/ml of protein) with 100 ml of ...
11
Caracterização bioquímica da atividade prócoagulante de proteases de fluidos laticíferos
... latex proteases with cysteine proteinase inhibitor E ...to cysteine proteases of latex and show a very intriguing in vivo protective activity of CpLP on platelet content on septic animals with ...
121
Caracterização bioquímica da atividade prócoagulante de proteases de fluidos laticíferos.
... latex proteases with cysteine proteinase inhibitor E ...to cysteine proteases of latex and show a very intriguing in vivo protective activity of CpLP on platelet content on septic animals with ...
120
Chemoenzymatic synthesis of organoselenium(IV) compounds and their evaluation as cysteine protease inhibitors
... A series of organoselenium dihalides (organoselenanes) was synthesized from organoselenides using a chemoenzymatic approach. The organoselenanes have variations in their stereochemistry and in the halogen atom bonded to ...
37
Streptozotocin-induced diabetes mellitus affects lysosomal enzymes in rat liver
... Dr. Maria A. Juliano) (17) as substrates. These substrates were used to quantify total cysteine proteases and ca- thepsin B, respectively. Incubation was carried out in dark microplates (Corning, USA), in ...
9
A biotechnology perspective of fungal proteases
... enzymes. Proteases in laundry detergents account for approximately 25% of the total worldwide sales of enzymes (Demain and Adrio, ...including proteases, amylases, cellulases, and li- pases (Hmidet et ...
11
Design, síntese e avaliação biológica de inibidores de proteases de cisteína
... estas proteases, em enzimas activadas a priori, por oposição por exemplo às proteases de serina que só na presença de substrato ficam com o seu centro activo ionizado ...
134
Respostas bioquímica, fisiológica e comportamental de Anticarsia gemmatalis (lagarta da soja) ao inibidor de serino proteases benzamidina
... Zhu–Salzman et al. (2003) estudando C. maculatus, utilizando cisteíno protease como principal enzima na digestão de proteínas, verificaram que altas concentrações de Soyacistatina N (ScN) na dieta deste inseto, induziam ...
85
Purificação e caracterização de proteases do veneno da Pseudechis australis e de...
... as proteases do veneno, frações obtidas pela cromatografia de exclusão molecular de 30mg de veneno foram submetidas a uma análise de espectrometria de massas em ...
51
Aplicação farmacêutica de inibidores de proteases : uma prospecção tecnológica
... Levando em consideração as bases consultadas, foi possível observar que até o presente momento houve um número insatisfatório de patentes envolvendo as aplicações farmacêuticas de inibidores de proteases, ...
8
Targeting exosites on blood coagulation proteases
... coagulation proteases has been attributed not only to residues surrounding the active site but also to other surface domains that are involved in recognizing and interacting with macromolec- ular substrates and ...
6