Dectin-1
Anion Exchanger 2 Regulates Dectin-1-Dependent Phagocytosis and Killing of Candida albicans.
... impairs Dectin-1 expression and phagocytic function of macrophages via pHi, including cytosolic and lysosomal ...impairs Dectin-1 transcription (Fig 5A) and Dectin-1 cell sur- ...
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Candida albicans Targets a Lipid Raft/Dectin-1 Platform to Enter Human Monocytes and Induce Antigen Specific T Cell Responses.
... particles by phagocytes is dispensable for the induction of several cytokines [50–54]. Moreover, with respect to the Dectin-1 receptor, it is known that signaling pathways leading to phagocyto- sis or ...
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Human dendritic cells activated via dectin-1 are efficient at priming Th17, cytotoxic CD8 T and B cell responses.
... as Dectin-1 are not just antigen uptake receptors but also modulators or initiators of adaptive immune ...to Dectin-1 has also been implicated in driving autoimmunity ...blocking ...
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Antibody constant region peptides can display immunomodulatory activity through activation of the Dectin-1 signalling pathway.
... in our experimental system. To this end, monocytes were pre- treated with N10K for 30 min and then stimulated for 18 h in the presence/absence of HI CA-6, zymosan, or curdlan, a Dectin-1 specific agonist ...
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Genetic association analysis of the functional c.714T>G polymorphism and mucosal expression of dectin-1 in inflammatory bowel disease.
... Background: Dectin-1 is a pattern recognition receptor (PRR) expressed by myeloid cells that specifically recognizes b-1,3 glucan, a polysaccharide and major component of the fungal cell ...activation, ...
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Association between polymorphisms in the genes encoding toll-like receptors and dectin-1 and susceptibility to invasive aspergillosis: a systematic review
... confirmed this finding when evaluating both donors and bone marrow transplant recipients (OR = 1.5, 95% CI = 0.5–5.0, p = 0.005). They revealed that dectin-1 receptor variation is a predisposing factor for ...
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Differential dependencies of monocytes and neutrophils on dectin-1, dectin-2 and complement for the recognition of fungal particles in inflammation.
... and dectin-1 expression by inflammatory neutrophils and ...of dectin-1-deficient cells is shown relative to wild type cells (100%) as mean695% confidence interval (raw representative data from ...
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Differential adaptation of Candida albicans in vivo modulates immune recognition by dectin-1.
... on Dectin-1 in vivo, despite the presence of exposed b-glucans on the fungal ...in Dectin-1 dependency in our mouse ...by Dectin-1 in ...
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Up-regulation of GITRL on dendritic cells by WGP improves anti-tumor immunity in murine Lewis lung carcinoma.
... [2], dectin-1 [3,4,5], lactosylceramide (LacCer) [6] and scavenger receptor (SR) ...However, dectin-1 is the main receptor mediating the activity on macrophages and dendritic cells (DCs) ...of ...
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Perspectives on Human Attachment (Pair Bonding): Eve's Unique Legacy of a Canine Analogue
... Candidates from the neuro-endocrine systems which have been suggested to affect affiliative behaviors include (i) neuro-peptides and hormones, e.g. oxytocin, vasopressin, and prolactin 1. (Insel 1997, Insel, ...
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Self-efficacy and arthritis disability: An updated synthesis of the evidence base and its relevance to optimal patient care
... In light of the increasing role of health behaviors as mediators of health status, and the fact that adults with arthritis are required to often carry out highly complex novel behaviors, but may not be confident to do ...
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Concept Analysis as Empirical Method
... In the NRC-Handelsblad of 16 May 1998, Thijs Goldschmidt (social scientist) pleaded for a long-term behavioral-biological research project into bullying behavior in the schoolyard, whil[r] ...
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Marked cytoreduction of a lymphocyte-rich mediastinal thymoma with neoadjuvant chemotherapy in a cat
... 95% reduction in volume of the mass. There was persis- tent cranial mediastinal lymphadenomegaly but the pre- viously reported tracheobronchial lymphadenomegaly and pleural fluid had resolved. A median sternotomy was ...
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How I Learned to Stop Worrying and Love the Bots
... Wagner, Mitter, Korner, and Strohmaier (2012) provided a succinct defini- tion of bots found on online social networks: “Social bots are automatic or semi-automatic computer programs t[r] ...
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General Symbol Machines: The First Stage in the Evolution of Symbolic Communication
... The second epistemic assumption is about evolutionary theorizing specifically. Some contemporary brands of evolutionary psychology have argued from observations of domain-specific adaptive behavior for domain-specific ...
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Confessions of a Closet Sociobiologist: Personal Perspectives on the Darwinian Movement in Psychology
... Evolutionary Approaches in the Behavioral Sciences: Toward a better understanding of human nature (pp.. New York: Elsevier?[r] ...
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Identity threat and stigma in cancer patients
... Cancer is a label given to several different diseases with the potential to carry a stigma. A modified version of contributors to the stigma-induced identity-threat model created by Major and O’Brien (2005) provides a ...
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From Mass to Social Media? Advancing Accounts of Social Change
... I suggest that Social Media and Society will be substantially focused on questions of social change. Thus, I urge a historical perspective that avoids the temptation to consolidate the vision of mass media as ...
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Cyclophosphamide-Induced Cardiomyopathy
... survival in 1 out of 3 patients with severe acute cardiomy- opathy. 12 The evidence for these therapies remains limited, and the mechanism of action is not well understood. In the presence of suspected cardiac ...
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Interpreters/Translators and Cross-Language Research: Reflexivity and Border Crossings
... In order to explore some of the issues raised by recognising that interpreters or translators involved in research are constructing and producing identity borders for themselves and oth[r] ...
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