Dendritic Cell (dc)
Liver accumulation of Plasmodium chabaudi-infected red blood cells and modulation of regulatory T cell and dendritic cell responses
... The cell suspensions were labeled further with anti-CD3 PE, anti-CD4 PerCP, and anti-CD8 APC MAbs to measure the frequencies of CD4+, CD8+ or DP cells among the conventional (GFP-) or regulatory (GFP+) T ...PE. ...
15
Preserved monocyte-derived dendritic cell differentiation and maturation in the presence of HIV-2 envelope
... Dendritic cell (DC) disturbances are thought to significantly contribute to AIDS pathogenesis (recently reviewed in [1, ...the cell surface due to its noncovalent association with the transmembrane ...
22
Hepatitis C lipo-Viro-particle from chronically infected patients interferes with TLR4 signaling in dendritic cell.
... Background. Hepatitis C virus (HCV) can be purified from serum of chronically-infected patients in the form of Lipo-Viro- Particles (LVP), which are triglycerid-rich lipoprotein-like particles containing viral RNA and ...
12
Crosslinked Hyaluronic Acid nanoparticles as delivery vehicles for dendritic cell-targeted vaccines
... The immune system has the ability to protect the body against different aggressions, in particular against external antigenic threats, either by microorganisms or macromolecules, or against internal aggressions. The ...
66
Using magnetic resonance imaging to evaluate dendritic cell-based vaccination.
... Dendritic cell (DC)-based vaccines can produce striking remissions of advanced disease [1,2], but the clinical response rate in most studies is less than 10% ...T cell responses, these procedures ...
12
Blastic plasmacytoid dendritic cell neoplasm
... plasmacytoid dendritic cell neoplasm is a rare and aggressive hematodermic neoplasia with fre- quent cutaneous involvement and leukemic ...plasmocytoid dendritic cell neoplastic precursor ...
4
Contact sensitizers downregulate the expression of the chemokine receptors CCR6 and CXCR4 in a skin dendritic cell line
... skin dendritic cell line (FSDC), kindly supplied by ...This cell line has a surface phenotype consistent with that of Langerhans cell progenitor (H-2 ...
5
Obesity impairs lymphatic fluid transport and dendritic cell migration to lymph nodes.
... We next used lymphoscintigraphy with Tc 99 labeled sulfur- colloid to analyze lymphatic function in obese and lean wild-type/ RAG mice since we have previously shown that this technique is highly sensitive and capable of ...
14
Dendritic Cell-Mediated Phagocytosis but Not Immune Activation Is Enhanced by Plasmin.
... mouse dendritic cell types in vitro and in ...Plasmin-treated dendritic cells did not undergo maturation and showed reduced migration to the draining lymph ...plasmin-treated dendritic cells ...
19
The sensitizer 2,4-dinitrofluorobenzene activates caspase-3 and induces cell death in a skin dendritic cell line
... a dendritic cell line derived from mouse skin (FSDC) was used, as an in vitro experimental model, to evalu- ate the cytotoxic effect of two chemical sensitizers, a strong sensi- tizer ...
7
Understanding how dendritic cell glycans affect antitumor immune responses
... induces dendritic cell maturation, thereby increasing the amount of some costimulatory molecules on the surface of these cells especially when stimulated with R848 ...
97
Synthetic virus-like particles target dendritic cell lipid rafts for rapid endocytosis primarily but not exclusively by macropinocytosis.
... Considering the difficulties in expressing tagged proteins in primary DC using transfected DNA plasmids, visualisation of different cell organelles had to rely on direct labelling in situ. Accordingly, labelling ...
16
Dermal dendritic cell number correlates with serum autoantibody titers in Brazilian pemphigus foliaceus patients
... DC produce cytokines which can induce T cell differentiation, and among them IL-12 has a primordial role by inducing the Th1 phenotype (8,9). In the serum of PF patients, IL-4, IL-5 and INF-γ are decreased, and ...
5
Dendritic cell podosome dynamics does not depend on the F-actin regulator SWAP-70.
... Swap-70 –/– osteoclasts are impaired in matrix degradation capacity and F-actin-ring formation [20]. To investigate whether DC podosomes of SWAP-70 deficient mice were similarly impaired in function, we examined their ...
7
Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations
... Recent data demonstrate that administration of chemo- therapeutic agents in conventional or low doses might sig- nificantly attenuate the antitumor potential of DC vaccines. For instance, gemcitabine increased survival ...
10
Type I and Type II Interferon Coordinately Regulate Suppressive Dendritic Cell Fate and Function during Viral Persistence.
... T cell suppressive potential and the induction of their immunosuppressive program is a collaboration between the interferon ...T cell stimulatory capacity, in essence shaping the immuno- suppressive ...T ...
26
Genome-wide analysis of alternative splicing during dendritic cell response to a bacterial challenge.
... DCs for hybridization in the microarrays were obtained as follows: Elutriated human monocytes (Advanced Biotechnology Inc., Columbia, MD) were grown in RPMI with 10% fetal bovine serum (Life Technologies, Paisley, UK) ...
11
The peptide sequence of diacyl lipopeptides determines dendritic cell TLR2-mediated NK activation.
... myeloid dendritic cells (mDC) in various ...NK cell activation was evaluated by three criteria: IFN-c production, up-regulation of NK activation markers and cytokines, and NK target (B16D8 cell) ...
12
HIV-1 Nef enhances dendritic cell-mediated viral transmission to CD4+ T cells and promotes T-cell activation.
... T cell activation is a critical feature of non-pathogenic primate lentiviruses and HIV-2, whereas HIV- 1 Nef induces T cell activation and contributes to viral pathogenicity ...down-regulates cell ...
10
Monitoring the initiation and kinetics of human dendritic cell-induced polarization of autologous naive CD4+ T cells.
... T cell stimulatory capacity shown in a pilot experiment (data not shown), we co-cultured pDC and naive T cells at a ratio of ...T cell stimulation ...the cell pellets were lysed in RLT buffer ...
13