Drug efficacy and safety
Efficacy and safety of a four-drug fixed-dose combination regimen versus separate drugs for treatment of pulmonary tuberculosis : a systematic review and meta-analysis
... For the analysis of the number of patients with gastroin- testinal AEs, all five studies collected related data and were included in the analysis. The fixed-effects model was chosen because heterogeneity was not ...
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The Future of Chronic Lymphocytic Leukemia Treatment- Balancing Efficacy, Safety and Cost
... the drug can be identiied ...therapy and towards diferent methods of treatment such as pulsed therapy and combinations that can shorten drug ...research and development costs, ...
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Efficacy and safety of patisiran for familial amyloidotic polyneuropathy: a phase II multi-dose study
... nausea, and vomiting), and the patient withdrew from the study because of the nausea and ...nausea and vomiting, and cellulitis were each recorded by the Investigator as related to the ...
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The efficacy and safety of linezolid and glycopeptides in the treatment of Staphylococcus aureus infections.
... lysis and antibiotic diffusibility [60] could alter drug concentration and potentially lead to confusing ...pulmonary drug concentration was higher in patients with pneumonia in linezolid arm ...
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Efficacy and safety of biodegradable polymer biolimus-eluting stents versus durable polymer drug-eluting stents: a meta-analysis.
... BES and the durable polymer SES, as well as other secondary outcomes, including all cause death, cardiac death, MI, clinically indicated TVR, clinically indicated TLR, and definite or probable ...
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Efficacy and safety of combined piroxicam, dexamethasone, orphenadrine, and cyanocobalamin treatment in mandibular molar surgery
... randomized and double-blind ...extraction and once daily for 4 consecutive ...scale and by the need for escape analgesia ...tape and adverse effects and patient satisfaction were ...
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Efficacy and Safety of Fingolimod in an Unselected Patient Population.
... conduction and its effect on the immune response raised some ...the safety and tolerability of fingolimod in these patient groups is less ...tolerability and efficacy of the ...year ...
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Predictive Factors for Efficacy and Safety of Prophylactic Theophylline for Extubation in Infants with Apnea of Prematurity.
... (Cmean), and the area under the curve (AUC) were calculated using y Q-flex software provided by The Japanese Society of Therapeutic Drug Monitoring (available from ...error and mean absolute ...
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Premarket safety and efficacy studies for ADHD medications in children.
... experimental drug, an active reference treatment, and a placebo comparator, are recommended by the ICH and by the European Medicines Agency specifically for the clinical investigation of ADHD ...
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Efficacy and Safety of Efavirenz in HIV Patients on Rifampin for Tuberculosis
... HIV and Mycobacterium tuberculosis co-infection management is to provide potent and safe antiretroviral therapy (ARV) and anti-tuberculosis treatment effective enough to cure and prevent ...
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Efficacy, safety and tolerability of sildenafil in Brazilian hypertensive patients on multiple antihypertensive drugs
... duration, and with hypertension that was being treated with at least 2 drugs from any of the following classes: diuretics, alpha-blockers, beta-blockers, angiotensin converting enzyme (ACE) inhibitors, or ...
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Evaluation of efficacy and safety of glycopyrrolate - xylazine - propofol anesthesia in buffalo calves
... of drug to onset of ataxia), down time (time elapsed from administration of drug to onset of sternal or lateral recumbency) and muscle ...reflex and closing of the ...horn and ...
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Schistosoma haematobium treatment in 1-5 year old children: safety and efficacy of the antihelminthic drug praziquantel.
... Chipinda and Chitate, in the Mashonaland East Province of Zimbabwe (31 u309E; 17u459S) where ...mansoni and soil transmitted helminths in this region ...control and immuno- epidemiology of human ...
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Treatment of cutaneous leishmaniasis with thermotherapy in Brazil: an efficacy and safety study
... the drug of choice for the treatment of ...cost and reduced efficacy over time attributable to incomplete ad- ministration of therapeutic regimens, their use should be restricted to those situations ...
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Safety and Efficacy of Human Wharton's Jelly-Derived Mesenchymal Stem Cells Therapy for Retinal Degeneration.
... photoreceptors and RPE are targeted and therefore yield better ...surface and also on the retinal surface ...the efficacy and the dose needed to reach therapeutic level may be high ...
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Use of safety strategies to identify children for drug administration
... where drug distribu- tion is centralized and unique manner, patient iden- tiication is ...use and the other for drugs for collective ...record and his/her irst ...
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Acucise™ endopyelotomy in a porcine model: procedure standardization and analysis of safety and immediate efficacy
... removed and a super-stiff guidewire was then passed through the 5F angiographic catheter and then coiled in the renal ...removed and the procedure was performed as de- ...procedure and it was ...
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SAFETY AND CLINICAL EFFICACY IN BIOSIMILAR SUBSTITUTION
... 2005 and increasing regulatory guidance on data requirements for their development and approval, many clinicians are still reluctant to consider biosimilars as a treatment option for their ...the ...
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Evaluation of the efficacy and safety of a standardised intracameral combination of mydriatics and anaesthetics for cataract surgery
... packaging and administration ...mydriasis and anaesthesia induced by Mydrane due to the removal of ...27 and hence, our outcomes may be considered under- ...centres and hospital-based clinics. ...
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An Investigation of Safety and Efficacy of Intravenous Paracetamol in Pain Management Following Cardiac Surgery
... In a recent study, the mean opioid consump- tion of patients with intravenous Paracetamol administration was lower than those with oral Paracetamol application (9). This result was also confirmed following orthopedic ...
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