Growth inhibition
Aurapten, a coumarin with growth inhibition against Leishmania major promastigotes
... Several natural compounds have been identified for the treatment of leishmaniasis. Among them are some alkaloids, chalcones, lactones, tetralones, and saponins. The new compound reported here, 7- geranyloxycoumarin, ...
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PPARc induces growth inhibition and apoptosis through upregulation of insulin-like growth factor-binding protein-3 in gastric cancer cells
... Insulin-like growth factor-binding protein-3 (IGFBP-3) is a tumor suppressor gene that has anti-apoptotic ...exhibited growth inhibition, induction of apoptosis, and a significant increase in IGFBP-3 ...
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Mechanisms of neuroblastoma cell growth inhibition by CARP-1 functional mimetics.
... Neuroblastomas (NBs) are a clinically heterogeneous group of extra cranial pediatric tumors. Patients with high-risk, metastatic NBs have a long-term survival rate of below 40%, and are often resistant to current ...
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RNAi-mediated silencing of the Bmi-1 gene causes growth inhibition
... Altogether, our study demonstrates that siRNA tar- geting of Bmi-1 led to the efficient and specific inhibition of endogenous Bmi-1 mRNA and protein expression of MCF-7 cells in vitro. Down-regulation of Bmi-1 ...
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EFFECT OF SIMVASTATIN ON THE GROWTH INHIBITION OF Candida albicans
... It was observed that in DMSO, there was a complete dilution of simvastatin, but since DMSO is a potent inhibitor, only the stock solu- tion (2500 μg / mL) was performed with this sol- vent, the other dilutions were made ...
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Mechanisms of growth inhibition of Phytomonas serpens by the alkaloids tomatine and tomatidine
... Membrane sterols in trypanosomatids are present as a complex mixture of 24-ethyl sterols and 24-methyl sterols, with cholesterol as a minor component. Our re- sults show an increase in cholesterol levels in parasites ...
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Rev. bras. farmacogn. vol.14 suppl.
... Senna (Cassia angustifolia Vahl.) is widely used as laxative, but data from Ames test and animal and/or human studies with this agent have shown a mutagenic and carcinogenic potentiality. Using thee experimental models ...
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Phase 1 study in malaria naive adults of BSAM2/Alhydrogel®+CPG 7909, a blood stage vaccine against P. falciparum malaria.
... the growth inhibition seen here was predominantly due to responses to the AMA1 components of the ...vaccine. Growth inhibition with induced antibody has not been shown to be associated with ...
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Braz. Dent. J. vol.25 número5
... The aim of this study was to investigate in vitro the antimicrobial effect and diffusion against E. faecalis of new intracanal medications on the external root surface. The medications tested were a placebo gel (PC); the ...
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Therapeutic efficacy by targeting correction of Notch1-induced aberrants in uveal tumors.
... Traditional approaches to treating UM consist of surgery, radiotherapy and chemotherapy [5,6]. However, these modes of treatment all have limitations, and are not particularly effective. As such, we set out to explore ...
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ANTIMICROBIAL ACTIVITY AND POTENTIAL USE OF MONOTERPENES AS TROPICAL FRUITS PRESERVATIVES
... mycelium growth inhibition, results in agreement with studies from Angioni et ...mycelium growth inhibition screening were conducted at the same dilutions used for the mycelial ...
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Nanoelectroablation of Murine Tumors Triggers a CD8-Dependent Inhibition of Secondary Tumor Growth.
... Fig 7. Immunohistochemical labeling of tumor thin sections with CD8 (red) antibodies and DAPI (blue) nuclear stain. A: Two typical sections from an untreated control tumor collected 14 days after injecting tumor cells ...
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Braz. oral res. vol.25 número6
... The mean OD readings were obtained to evaluate cell growth inhibition after various treatments, i.e., the extracts, reference substance and experimental controls. A primary battery of experiments was used ...
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Braz. J. Chem. Eng. vol.21 número2
... the growth phase in group II experiment E-2-C worked out, in spite of some cell growth inhibition, indicating production dependence on dissolved oxygen concentration in the culture medium, even under ...
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Integrating constitutive gene expression and chemoactivity: mining the NCI60 anticancer screen.
... NCI60 GI50 values are used to define in vitro tumor cell chemoactivity for compounds screened by the Developmental Therapeutics Program (DTP). The complete GI50 data set is available in the PubChem repository [4]. Data ...
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Antifungal activity of Helichrysum italicum (Roth) G. Don (Asteraceae) essential oil against fungi isolated from cultural heritage objects
... during anthesis and rich in β-selinene, α-pinene and γ-curcumene (chemotype C1) have strong antibacte- rial activity. he tested fungi showed diferent suscep- tibility to oil treatment. T. viride appeared to be the most ...
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RGO, Rev. Gaúch. Odontol. vol.63 número2
... the growth inhibition of microorganisms of the oral cavity, justiied by the high pH and because the calcium hydroxide is the main component released from the MTA in aqueous medium 4 ...
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Evandro Leite de SOUZA1 , Tânia Lúcia Montenegro STAMFORD2 , Edeltrudes de Oliveira LIMA3, José Maria BARBOSA FILHO4 , Márcia Ortiz Mayo MARQUES5
... large growth inhibition zones (30-42 ...microbial growth inhibition zones with similar or close diameters when evaluating the essential oil kept at room temperature and after exposure to ...
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Synergistic effect of afatinib with su11274 in non-small cell lung cancer cells resistant to gefitinib or erlotinib.
... Epidermal growth factor receptor (EGFR) and c-MET receptors are expressed on many non-small cell lung cancer (NSCLC) ...and inhibition by ...cell growth inhibition, apoptosis induction and ...
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Antifungal activity of extracts from Brazilian Cerrado plants on Colletotrichum gloeosporioides and Corynespora cassiicola
... mycelial growth and the spore ...mycelial growth inhibition and spore germination inhibition were obtained based on the comparison with the ...mycelial growth stimulation for ...
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