Hepatic fibrosis
Experimental Hepatic Fibrosis Due to Capillaria hepatica Infection (Differential Features Presented by Rats and Mice)
... Progressive hepatic fibrosis and cirrhosis constitute the most serious consequence of many chronic diseases affecting the ...of fibrosis, still require further investigation (Friedman 1993, 2000, ...
8
Inhibitory effect of liposomal quercetin on acute hepatitis and hepatic fibrosis induced by concanavalin A
... and hepatic fibrosis induced by immunological ...A hepatic fibrosis model was also generated in mice by Con A challenge once a week for 6 consecutive ...and hepatic stellate cells ...
7
The role of oxymatrine in regulating TGF-β1 in rats with hepatic fibrosis
... against hepatic fibrosis. Oxymatrine (OMT) is an alkaloid extracted from the roots of the Chinese herb Sophora subprostrata, and has anti-inflammatory, anti-bacterial, anti-viral, immunosuppressive, and ...
9
Impact of a CXCL12/CXCR4 Antagonist in Bleomycin (BLM) Induced Pulmonary Fibrosis and Carbon Tetrachloride (CCl4) Induced Hepatic Fibrosis in Mice.
... The 7-transmembrane G-protein coupled chemokine receptor, CXCR4 and its ligand CXCL12 (SDF-1α-stromal cell derived factor-1α) [29, 30] are involved in the homing of hematopoietic stem cells to the bone marrow, ...
19
Performance of real-time elastography for the staging of hepatic fibrosis: a meta-analysis.
... liver fibrosis [6–8]; however, LB is an invasive procedure possibly leading to patients’ ...of hepatic fibrosis as alternatives to biopsy [11, 12], including serum biomarkers, scoring systems and ...
15
WNT signaling pathway gene polymorphisms and risk of hepatic fibrosis and inflammation in HCV-infected patients.
... advanced hepatic fibrosis (advanced F3/F4-F4 vs. mild F0-F3 fibrosis) and also of advanced hepatic inflammation (advanced A2/A3- A3 ...
9
Attenuation of CCl4-induced hepatic fibrosis in mice by vaccinating against TGF-β1.
... experimental hepatic fibrosis, we believe this measure will also be applicable for the treatment of hepatic ...for hepatic fibrosis is whether the vaccines are able to elicit Ab ...
13
The efficacy of aspartate aminotransferase-toplatelet ratio index for assessing hepatic fibrosis in childhood nonalcoholic steatohepatitis for medical practice
... Analysis of the data was performed with PASW ver. 18.0 (IBM Co., Armonk, NY, USA). Univariate analysis was con- ducted to evaluate the significance of group differences. Logistic regression models were performed for ...
7
The effect of down-regulation of Smad3 by RNAi on hepatic stellate cells and a carbon tetrachloride-induced rat model of hepatic fibrosis
... for hepatic fibrosis, we constructed siRNA expression plasmids targeting the rat Smad3 gene and then delivered these plasmids into hepatic stellate cells ...untreated hepatic fibrosis ...
10
Correlation of biological serum markers with the degree of hepatic fibrosis and necroinflammatory activity in hepatitis C and schistosomiasis patients
... stage fibrosis; however, it is an invasive procedure and is potentially ...of hepatic fibrosis in schistosomiasis and hepatitis C (HC) as isolated diseases or ...evaluate fibrosis and ...
7
Malnutrition and Hepatic Fibrosis in Murine Schistosomiasis
... liver fibrosis in undernour- ished mice are reported: shifting from a deficient to a balanced diet and vice-versa, repeated infections, influence of the genetic background, and immunological ...“pipestem” ...
8
Brivanib attenuates hepatic fibrosis in vivo and stellate cell activation in vitro by inhibition of FGF, VEGF and PDGF signaling.
... respectively. Hepatic deposition of collagen was assessed in liver specimens by Sirius red and Masson’s trichrome staining with quantitation of the numbers of bands of liver ...bridging fibrosis seen after ...
12
Apoptosis and Progression of Hepatic Fibrosis in Hepatitis C Patients
... Six types of DRs have been identified, but only the following are considered to play a role on liver apoptosis: 1. Fas (CD95), 2. Tumor necrosis factor receptor (TNF_R1), 3. Receptor-1 binding inducing TNF (TRAIL-R1), ...
5
No correlation between PNPLA3 rs738409 genotype and fatty liver and hepatic cirrhosis in Japanese patients with HCV.
... the hepatic and portal vein walls ...and hepatic cirrhosis ...of hepatic fibrosis in chronic hepatitis C patients with hepatic ...
7
J. Bras. Patol. Med. Lab. vol.38 número4
... late fibrosis did not reach statistical ...early hepatic fibrosis from undergoing the characteristic ultrastructural changes seen during “acute” collagen degradation, as compared to other ...
8
Cytokine Profile Associated with Human Chronic Schistosomiasis Mansoni
... ribs) and no past digestive bleeding or other signs of severe portal hypertension. The inclusion criteria were to have positive Kato-Katz parasitological examinations for schistosomiasis, no history of therapy for ...
6
Rev. Soc. Bras. Med. Trop. vol.37 número2
... hepatic fibrosis induc ed by repeated intraperitoneal injec tions of pig serum presented portal pressure, oxygen c onsumption and liver weight c omparable to normal c ...of hepatic fibrosis ...
5
Remodeling of hepatic vascular changes after specific chemotherapy of schistosomal periportal fibrosis
... standing hepatic fibrosis being degraded and removed has been ...occurring. Hepatic vascular alterations associated with advanced schisto- somiasis have already been ...of fibrosis regression. ...
6
Rev. Soc. Bras. Med. Trop. vol.36 número5
... hepatic fibrosis. Under the same experimental protocol, septal fibrosis developed in 65% of the animals when the serum was injected instead into the peritoneal ...the fibrosis stimulating ...
4
Arq Bras Endocrinol Metab vol.55 número6
... Objectives: To determine the prevalence of insulin resistance (IR) in non-diabetic patients with chronic hepatitis C, and to assess the association between IR, laboratory parameters and histo- logical findings. Subjects ...
7