IL-17A
Impacto da IL-17A na predisposição ao diabetes mellitus tipo 1A
... interleucina 17A é uma citocina pró-inflamatória implicada, juntamente com seu receptor 20 , em diversas doenças autoimunes, tais como artrite reumatóide, psoríase e lupus ...a IL-17A é fortemente ...
136
Lower production of IL-17A and increased susceptibility to Mycobacterium bovis in mice coinfected with Strongyloides venezuelensis
... the IL-17A levels and the presence of only small granulomas observed in coinfected mice could be a factor involved in the increased susceptibil- ity to ...model. IL-17, the main cytokine produced by ...
4
Heterogeneity of multifunctional IL-17A producing S. Typhi-specific CD8+ T cells in volunteers following Ty21a typhoid immunization.
... with IL-17A-PerCP-Cy5.5 (eBio64DEC17, eBioscience), IL-2-PE-Cy7 (MQ1-17H12, BD), IFN-c-Alexa 647 or APC-Alexa 750 (B27, BD or Invitrogen), TNF-a-Alexa 700 (MAb11, BD), IL- 10-FITC (127107, ...
17
Correction: Defining the Roles of IFN-γ and IL-17A in Inflammation and Protection against Helicobacter pylori Infection.
... of IL-17A secretion in stomach tissue extracts and ...neutralizing IL-17A antibody compared to immunized mice injected isotype control antibody was calculated by an unpaired two-tailed t-test ...
3
γδ T cells are required for pulmonary IL-17A expression after ozone exposure in mice: role of TNFα.
... cd T cells are a key component of the innate immune response, especially at mucosal surfaces. These cells are found throughout the lung, particularly in the subepithelial region, where they may regulate other immune ...
9
Epicutaneous exposure to staphylococcal superantigen enterotoxin B enhances allergic lung inflammation via an IL-17A dependent mechanism.
... AD, IL-17 expression was induced not only in the skin but also in the airways, which was independent of IL-4 and IL-13 [34], implicating IL-17 in the atopic ...of IL-17A by ...
13
Plasma levels of IL-37 and correlation with TNF-α, IL-17A, and disease activity during DMARD treatment of rheumatoid arthritis.
... TNF-a, IL-6 and IL-17A have been considered to be the pivotal cytokines in the pathogenesis of RA, as they are present at biologically significant levels in RA synovial tissue and in synovial fluid ...
7
IL-17A promotes the migration and invasiveness of cervical cancer cells by coordinately activating MMPs expression via the p38/NF-κB signal pathway.
... that IL-17A could enhance the migration and invasion abilities of cervical cancer cells ...that IL-17A could promote the migration and invasion abilities of human breast cancer and ...
8
One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4+ T Cells, and IL-17A.
... IFN-γ-PE, IL-2-APC, TNF-AF700, CD44-V450 (BD Pharmingen), CD8-PE Texas Red (Invitrogen), IL-17A-PE Cy7, IL-4-AF488 and IL-13-AF488 (eBioscience) in Perm/Wash buffer (BD Biosciences) for ...
18
IL-17A and serum amyloid A are elevated in a cigarette smoke cessation model associated with the persistence of pigmented macrophages, neutrophils and activated NK cells.
... as IL-8 (CXCL8), KC (CXCL1) and MIP-2a (CXCL2) are implicated in COPD as they are elevated in CS exposure models [15] and during exacerbations ...active IL-17A + cells increase in frequency in the ...
11
IL-17A/F-signaling does not contribute to the initial phase of mucosal inflammation triggered by S. Typhimurium.
... of IL-17RA signaling in enterocytes reduced the pathology of DSS-induced colitis [16] and IL-17A and -F are known to induce enterocyte expression of antimicrobial peptides and numerous ...
10
Análise de VEGF-C, COX-2 e IL-17A como Biomarcadores do Carcinoma Epidermóide de Cabeça e Pescoço
... and IL-17A as possible BM of HNSCC, since their high expression has been related to a worse prognosis of the ...of IL-17A (pg/ml) was measured by flow ...of IL-17A was higher in ...
76
Th17/IL-17A might play a protective role in chronic lymphocytic leukemia immunity.
... twice in PBS, divided into tubes, and then stained with monoclonal antibodies (MoAb) against the cell-surface markers CD4 FITC and CD3 PE-Cy5 (BD Pharmingen). Following membrane staining, cells were fixed and ...
8
Plasma IL-17A levels in patients with late-life depression
... including IL-6, TNF-a, IL-1b, the soluble IL-2 receptor, and C-reactive protein, compared to controls; however, there is limited information on IL-17A in ...about IL-17A ...
4
Chemoresistance of human monocyte-derived dendritic cells is regulated by IL-17A.
... of IL-17A-stimulated dendritic cells, in the presence of IFN- c, in ...with IL-17A and ...on IL-17A-treated DC, with or without IFN-c (data not ...
11
Associations between polymorphisms of IL-17F and IL-17A genes with disease activity and clinical outcome of Ankylosing Spondylitis
... the IL- -17F gene polymorphisms at positions IL-17F 7383A/G and IL-17F 7488A/G and the IL-17A gene polymor- phisms at position G197A in AS susceptibility and severity for the first time ...
8
Estudo de polimorfismos nos genes IL17A e IL17RA e da produção de IL-17A, IL-33 e CCL2 em gestantes infectadas pelo Toxoplasma gondii do Estado do Rio Grande do Norte, Brasil
... As IL-17A, IL-33 e a quimiocina CCL2 foram quantificadas no plasma ou soro (FIGURA 4) dos indivíduos da população de gestantes utilizando-se kit de ELISA da PeproTec (Ribeirão Preto, Brazil) ...
90
Expressão de interleucina-17A em pacientes com polipose nasossinusal.
... of IL-17A in chronic inflammatory ...of IL-17A in the SNP and verify if this expression is a marker of good or bad ...The IL-17A expression was observed in both atopic and ...
4
Avaliação dos níveis séricos de IL-17, IL-22, IL-23p19, IL-27 e TGF-β em pacientes no Lúpus Eritematoso Sistêmico
... e IL-6, citocinas com efeitos opostos, tem efeito sinérgico para induzir receptor nuclear órfão RORyt, que coordena a expressão de IL-17A e IL-17F em células T naïve (Veldhoen et ...e ...
126
Associação entre perdas precoces de implantes dentários e polimorfismos genéticos de IL-8, IL-17 e IL-23
... da IL-17A na diferenciação e função dessas ...a IL-17A induz a diferenciação de osteoblastos de humanos por células-tronco mesenquimais sugerindo que IL-17A teria um efeito ...
91