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INKT cells

Colonic inflammation in mice is improved by cigarette smoke through iNKT cells recruitment.

Colonic inflammation in mice is improved by cigarette smoke through iNKT cells recruitment.

... between iNKT cells and the control of DSS-induced ...by iNKT cells themselves, we stained IL-10 in colonic iNKT cells from smoking and control ...other cells orchestrated ...

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iNKT cells suppress the CD8+ T cell response to a murine Burkitt's-like B cell lymphoma.

iNKT cells suppress the CD8+ T cell response to a murine Burkitt's-like B cell lymphoma.

... these cells is regulated by iNKT and type II NKT ...Similar iNKT versus type II NKT cell antagonism has been noted before [13,14,24,25], but our data differ from the published literature in several ...

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Activated iNKT cells promote memory CD8+ T cell differentiation during viral infection.

Activated iNKT cells promote memory CD8+ T cell differentiation during viral infection.

... that iNKT cells are dispensable in controlling acute MCMV infection, and therefore should not interfere with mounting an appropriate acute response ...

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iNKT Cells Are Responsible for the Apoptotic Reduction of Basophils That Mediate Th2 Immune Responses Elicited by Papain in Mice Following γPGA Stimulation.

iNKT Cells Are Responsible for the Apoptotic Reduction of Basophils That Mediate Th2 Immune Responses Elicited by Papain in Mice Following γPGA Stimulation.

... whether iNKT cell-derived cytokines such as IFNγ and TNFα induce the increased apo- ptosis of ...of iNKT cells and the neutralization of iNKT cell-derived cytokines can affect the basophil ...

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Production of α-galactosylceramide by a prominent member of the human gut microbiota.

Production of α-galactosylceramide by a prominent member of the human gut microbiota.

... implicating iNKT cells in immunity (‘‘a-galactosylceramide’’ has 3,290 citations in Google Scholar, ...of cells in the gut community of a typical human ...activates iNKT cells ...

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Innate immunity drives the initiation of a murine model of primary biliary cirrhosis.

Innate immunity drives the initiation of a murine model of primary biliary cirrhosis.

... Further, iNKT cell defi- cient CD1d knockout mice have decreased inflammatory portal cell infiltrates and reduced anti-mitochondrial antibody ...of iNKT cells can occur via overlapping and/or ...

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Mouse and Human CD1d-Self-Lipid Complexes Are Recognized Differently by Murine Invariant Natural Killer T Cell Receptors.

Mouse and Human CD1d-Self-Lipid Complexes Are Recognized Differently by Murine Invariant Natural Killer T Cell Receptors.

... (iNKT) cells recognize self-lipids presented by CD1d through char- acteristic TCRs, which mainly consist of the invariant Vα14-Jα18 TCRα chain and ...The iNKT cell-CD1d axis is conserved between ...

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Avaliação do perfil de células iNKT em crianças com asma severa

Avaliação do perfil de células iNKT em crianças com asma severa

... + iNKT + cells (mean ...of iNKT cells ...of iNKT cells ...of iNKT cells was not different between atopic (n = 127) and non-atopic (n = 45) ...addition, iNKT ...

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Identificação de iGb3 e iGb4 em células de melanoma murino B16F10- Nex2 e efeito antitumoral de células dendríticas primadas com iGb3 mediado por células iNKT

Identificação de iGb3 e iGb4 em células de melanoma murino B16F10- Nex2 e efeito antitumoral de células dendríticas primadas com iGb3 mediado por células iNKT

... CD1d-restricted iNKT cells are protective against the murine melanoma B16F10- Nex2 growing subcutaneously in syngeneic ...dendritic cells, of lipidic antigens to iNKT ...melanoma cells ...

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Identification of iGb3 and iGb4 in melanoma B16F10-Nex2 cells and the iNKT cell-mediated antitumor effect of dendritic cells primed with iGb3

Identification of iGb3 and iGb4 in melanoma B16F10-Nex2 cells and the iNKT cell-mediated antitumor effect of dendritic cells primed with iGb3

... of iNKT cells in the B16F10-Nex2 system, endogenous lipid components of tumor cells should be recognized and we hypothesized that they could be glycosphingolipids expressed on tumor cells, ...

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Major Article Prostaglandin A

Major Article Prostaglandin A

... control cells, and heat shock treatment induced higher HSP70 expression levels than those observed following PGA 1 ...Hep-2 cells may be sufficient to inhibit MAYV ...

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Resolving tumor heterogeneity: genes involved in chordoma cell development identified by low-template analysis of morphologically distinct cells.

Resolving tumor heterogeneity: genes involved in chordoma cell development identified by low-template analysis of morphologically distinct cells.

... physaliferous cells via intermediate cells being the main prolifer- Figure ...MUG-Chor1 cells. Cells were tracked over a period of seven days with images taken every 30 ...All cells ...

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Mesenchymal stem cell 1 (MSC1)-based therapy attenuates tumor growth whereas MSC2-treatment promotes tumor growth and metastasis.

Mesenchymal stem cell 1 (MSC1)-based therapy attenuates tumor growth whereas MSC2-treatment promotes tumor growth and metastasis.

... mast cells (MCs), and MSCs also affect ECM proteins, yet another component of the TME important to tumor growth and spread ...mast cells and collagen (ECM) levels among the MSC-treated tumor groups were ...

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Linfócitos B: do laboratório à prática clínica.

Linfócitos B: do laboratório à prática clínica.

... B cells develop in bone marrow and undergo anti- gen-induced activation and terminal differentiati- on in germinal centres of secondary lymphoid or- ...B cells with the same antigen specifi- city (clonal ...

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RasGRP1, but not RasGRP3, is required for efficient thymic β-selection and ERK activation downstream of CXCR4.

RasGRP1, but not RasGRP3, is required for efficient thymic β-selection and ERK activation downstream of CXCR4.

... B cells while RasGRP3 is prominently expressed in B ...T cells suggests that RasGRP1 and Sos operate in a feedforward loop where initial RasGRP1-mediated Ras activation potentiates ...

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Dynamics and kinetics of natural killer cell cytotoxicity in human malaria as evaluated by a novel stepwise cytotoxicity assay

Dynamics and kinetics of natural killer cell cytotoxicity in human malaria as evaluated by a novel stepwise cytotoxicity assay

... especially among malaria infected individuals. Patients presented at different periods of infection, with various parasitemia, and the blood was collected at different times after schizogony. This variation makes ...

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Ocular Fluid As a Replacement for Serum in Cell Cryopreservation Media.

Ocular Fluid As a Replacement for Serum in Cell Cryopreservation Media.

... Stem cells are used in transplantation and cell-based therapies, which makes these cells a prom- ising tool for regenerative and biomedical ...stem cells have a limited lifespan [2], and with ...

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Rev. Soc. Bras. Med. Trop.  vol.39 número4

Rev. Soc. Bras. Med. Trop. vol.39 número4

... especially among malaria infected individuals. Patients presented at different periods of infection, with various parasitemia, and the blood was collected at different times after schizogony. This variation makes ...

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Biochemical mechanisms underlying atherogenesis

Biochemical mechanisms underlying atherogenesis

... of cells to en- dothelium that include platelets and mono- ...muscle cells and monocytes, formation of prostaglandins such as thromboxane A2, one of the most potent vasoconstricting and platelet- ...

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The membrane-associated transient receptor potential vanilloid channel is the central heat shock receptor controlling the cellular heat shock response in epithelial cells.

The membrane-associated transient receptor potential vanilloid channel is the central heat shock receptor controlling the cellular heat shock response in epithelial cells.

... neuronal cells, but it may also act on neuronal as well as non-neuronal cells as a molecular sensor of temperature variation and of other non-thermal cellular stresses, such as inflammatory stimuli ...

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