MHC class II
MHC Class II haplotypes of Colombian Amerindian tribes
... The NJ tree generated based on MHC class II fre- quencies (Figure 2) showed mainly the presence of two clusters. In one of them, the Chibcha speaking tribes of Northern Colombia (Arhuaco, Kogui, ...
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GPS-MBA: computational analysis of MHC class II epitopes in type 1 diabetes.
... the MHC class II haplotype, I-A g7 , is strongly linked to susceptibility to T1D in the non-obese diabetic (NOD) mouse ...Phase II trials, and three Phase III trials are still ongoing ...
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Limitations of Ab initio predictions of peptide binding to MHC class II molecules.
... peptide MHC binding typically require a large set of binding data for the specific MHC molecule that is ...an MHC molecule based on the highly conserved 3D structure of peptide:MHC ...for MHC ...
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Schistosoma japonicum soluble egg antigens attenuate IFN-γ-induced MHC class II expression in RAW 264.7 macrophages.
... up-regulating MHC class II expression and is necessary for the host’s defense to pathogens ...on MHC class II, we selected IFN-c as an inducer of MHC class ...
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Transport of Streptococcus pneumoniae capsular polysaccharide in MHC Class II tubules.
... T cells in a major histocompatibility complex (MHC) class II–dependent manner. The mechanism of carbohydrate presentation to CD4 þ T cells is unknown. We show in live murine dendritic cells (DCs) ...
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Trans-species polymorphism and selection in the MHC class II DRA genes of domestic sheep.
... the class II MHC DRA gene is highly conserved with only limited allelic ...of MHC class II DR protein expression were detected at the surface of leukocyte populations obtained ...
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MHC class II-restricted presentation of the major house dust mite allergen Der p 1 Is GILT-dependent: implications for allergic asthma.
... optimal MHC class II-restricted responses, Der f 1, which is structurally related to Der p 1, did not ...for MHC class II-restricted presentation of some, but not all, ...the ...
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Interferon-γ induces expression of MHC class II on intestinal epithelial cells and protects mice from colitis.
... Single cell suspensions were incubated with anti-FccRII/III (2.4G2). The following antibodies (clones) were used for surface staining: anti-CD3e (145-2C11), anti-CD4 (RM4-5), anti-CD8 (53-6.7), anti-CD11b (M1/70), ...
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Preserved MHC class II antigen processing in monocytes from HIV-infected individuals.
... In the literature there are varying reports from an increased level of HLA-DR on APC from HIV-infected individuals to somewhat diminished levels [5,16,17,18,19,20,21]. It is not clear why MN from HIV-infected individuals ...
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Enhanced vaccine-induced CD8+ T cell responses to malaria antigen ME-TRAP by fusion to MHC class ii invariant chain.
... macaque Ii chain proteins (86%), cross-reactivity to a pool of peptides spanning the human Ii sequence was observed in one rhesus macaque vaccinated with ...human Ii and absent from macaque ...for ...
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NLRC5 exclusively transactivates MHC class I and related genes through a distinctive SXY module.
... (MHC) class II (MHCII) genes, and mutations in the CIITA gene lead to severe immunodeficiency ...of MHC class I (MHCI) genes, primar- ily in lymphocytes, where it is highly expressed ...
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Role of interplay between IL-4 and IFN-gamma in the in regulating M1 macrophage polarization induced by Nattectin
... of MHC class II, CD80, CD86 and CD40 ...in MHC class II and CD49a integrin expression with MMP-9 production and endocytic capacity depend on lec- tin function of ...and ...
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Resident CD8(+) and migratory CD103(+) dendritic cells control CD8 T cell immunity during acute influenza infection.
... Histocompatibility Class II molecules (MHC ...of MHC II on cDCs is variable and dependent on maturation ...surface MHC class II (MHC II int ...
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Helper T cell epitope-mapping reveals MHC-peptide binding affinities that correlate with T helper cell responses to pneumococcal surface protein A.
... peptide MHC class II interactions that determine protective pneumococcal immunity are not known, this study addresses important questions that are relevant to MHC polymorphisms and antigen ...
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Efeito da sílica nanoestruturada SBA-15 na apresentação antigênica e na resposta...
... of MHC class II and co-stimulatory molecules by the APCs and the influence of contact time between immunogen:SBA-15 in the potential for absorption and generation of specific ...
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Exosomes derived from M. Bovis BCG infected macrophages activate antigen-specific CD4+ and CD8+ T cells in vitro and in vivo.
... marker of DC activation. As expected, non-activated DCs were positive for CD11c and negative for intracellular IL-12p40 (Fig. 5A). The same profile was seen for DCs treated with exosomes isolated from uninfected J774 ...
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The effect of CpG-ODN on antigen presenting cells of the foal
... surface MHC class II and co-stimulatory molecules (CD83, CD86) for efficient antigen presentation to T lymphocytes ...of MHC class II and co-stimulatory molecule on the cell ...
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Cathepsin B in antigen-presenting cells controls mediators of the Th1 immune response during Leishmania major infection.
... molecules MHC class II as well as co- stimulatory molecules such as CD86, CD80 and CD40 ...of MHC class II molecules was greatly enhanced in BMDC from Ctsb 2/2 mice and, to a ...
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Mobilization of regulatory T cells in response to carotid injury does not influence subsequent neointima formation.
... T cells with partially opposing effect on neointima formation and that the lack of effect observed in MHC class II deficient mice is explained by a loss of all of these cells. To determine if a ...
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Dissecting inflammatory complications in critically injured patients by within-patient gene expression changes: a longitudinal clinical genomics study.
... We found that approximately one quarter of the genome changes during early stages of treatment in concordance with the observed variation in 28-d clinical outcomes. These expression changes are coordinated into five ...
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