MHC class II molecule
The effect of CpG-ODN on antigen presenting cells of the foal
... of MHC class II molecule in the APCs of the newborn and young foal, although the expression of the co-stimulatory molecule CD86 seems to be present already in early ...
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GPS-MBA: computational analysis of MHC class II epitopes in type 1 diabetes.
... novel MHC class I epitopes derived from type 1 diabetes autoantigens ...expressed MHC class II molecule in the NOD mouse [9,10], additional efforts have subsequently been ...
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Limitations of Ab initio predictions of peptide binding to MHC class II molecules.
... Molecular dynamics simulation. The molecular dynamics (MD) simulation was performed with the software package NAMD [38] using the CHARMM22 force field [39] with an explicit water model. The structure of the MHC ...
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Helper T cell epitope-mapping reveals MHC-peptide binding affinities that correlate with T helper cell responses to pneumococcal surface protein A.
... to MHC class II molecules is not dependent on exact size, derivation of MHC class II ARB matrices followed an iterative ...each MHC class II molecule ...
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Transport of Streptococcus pneumoniae capsular polysaccharide in MHC Class II tubules.
... adjacent hydroxyl groups on residue c (molecular weight 175) were oxidized by sodium m-periodate (Sigma, http://www.sigmaaldrich. com) treatment in molar ratios ranging from 1:0.1 to 1:0.5 for 90 min at room temperature ...
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Model for the peptide-free conformation of class II MHC proteins.
... Methodology/Principal Findings: Here we use molecular dynamics simulations and experimental probes of protein conformation to investigate the peptide-free state of class II MHC proteins. Upon ...
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Preserved MHC class II antigen processing in monocytes from HIV-infected individuals.
... of MHC-II expression, increase in invariant chain expression, decrease in antigen uptake, and decreased antigen presentation ...of MHC-II antigen processing and presentation are similar to the ...
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Cerebrospinal fluid dendritic cells infiltrate the brain parenchyma and target the cervical lymph nodes under neuroinflammatory conditions.
... human Flt-3 ligand (10 ng/ml). By the end of this period, clusters of non adherent cells had formed that were removed, dispersed and re-plated in fresh media consisting of DMEM supplemented with 10% FCS (BioWest), ...
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MHC Class II haplotypes of Colombian Amerindian tribes
... The NJ tree generated based on MHC class II fre- quencies (Figure 2) showed mainly the presence of two clusters. In one of them, the Chibcha speaking tribes of Northern Colombia (Arhuaco, Kogui, ...
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Rev Bras Med Esporte vol.18 número3
... Introduction: Over the last century, people have become less active, adopting more sedentary habits. This scenario has increased the incidence of chronic diseases such as cardiovascular diseases, type 2 diabetes and ...
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Design of glycopeptides used to investigate class II MHC binding and T-cell responses associated with autoimmune arthritis.
... The binding of the glycopeptides to A q or DR4 was determined relative to a biotinylated marker peptide in a competitive inhibition assay performed essentially as described elsewhere [10,69]. Briefly, a mixture of a ...
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Papel do MHC de classe II na biogênese do vacúolo parasitóforo de
... moléculas MHC II sofrem redistribuição, onde uma significativa proporção dessas moléculas, cerca de 95% associa se com os VPs, em 48 ...de MHC II, assim como as moléculas H 2M, são ...
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Cathepsin B in antigen-presenting cells controls mediators of the Th1 immune response during Leishmania major infection.
... molecules MHC class II as well as co- stimulatory molecules such as CD86, CD80 and CD40 ...of MHC class II molecules was greatly enhanced in BMDC from Ctsb 2/2 mice and, to a ...
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Schistosoma japonicum soluble egg antigens attenuate IFN-γ-induced MHC class II expression in RAW 264.7 macrophages.
... IFN-c-induced MHC class II expression by inducing IL-10 and IL-6 ...that MHC class II expression in RAW ...of MHC class II in initiation and regulation of ...
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Exosomes derived from M. Bovis BCG infected macrophages activate antigen-specific CD4+ and CD8+ T cells in vitro and in vivo.
... responses within the granuloma but distal to the infection foci. Thus cross-priming by exosomes may help promote the robust immune response seen in infected individuals. Moreover, we suggest that exosomes may be a viable ...
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Interferon-γ induces expression of MHC class II on intestinal epithelial cells and protects mice from colitis.
... Single cell suspensions were incubated with anti-FccRII/III (2.4G2). The following antibodies (clones) were used for surface staining: anti-CD3e (145-2C11), anti-CD4 (RM4-5), anti-CD8 (53-6.7), anti-CD11b (M1/70), ...
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Mobilization of regulatory T cells in response to carotid injury does not influence subsequent neointima formation.
... T cells with partially opposing effect on neointima formation and that the lack of effect observed in MHC class II deficient mice is explained by a loss of all of these cells. To determine if a ...
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Efeito da sílica nanoestruturada SBA-15 na apresentação antigênica e na resposta...
... de MHC de classe II e coestimuladoras pelas APCs; seguiram –se estudos da influência do tempo de contato imunógeno:SBA –15 no potencial de adsorção e geração de ...
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Enhanced vaccine-induced CD8+ T cell responses to malaria antigen ME-TRAP by fusion to MHC class ii invariant chain.
... T cell responses were enumerated by ICS at the same timepoint, though there was a trend in the same direction as the ELISpot results (Fig. 6b centre and right). TRAP-specific ELIspot responses declined after week 2 until ...
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Cephalometric evaluation of skeletal alterations induced by Herbst appliance during mixed dentition
... were: Class II facial pattern, associated with man- dibular retrusion; Class II division 1 malocclusion; erupted permanent maxillary and mandibular cen- tral incisors; mixed dentition and ...
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