MHC I-/- or MHC II -/- mice
Resposta imune intestinal de camundongos geneticamente deficientes em complexo de histocompatibilidade principal (MHC classe I ou II) infectados por Strongyloides venezuelensis
... class I or class II deficient ...(WT), MHC I -/- and MHC II -/- mice were individually inoculated with ...of mice infected with ...that MHC II ...
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Interferon-γ induces expression of MHC class II on intestinal epithelial cells and protects mice from colitis.
... Tg mice correlates with the loss of inducible MHCII expression by ...control mice upregulated MHCII expression, while this was not observed in colitic pIV2/2 K14 CIITA Tg mice or healthy ...
10
Probing natural killer cell education by Ly49 receptor expression analysis and computational modelling in single MHC class I mice.
... for MHC class I molecules, which allows for ‘‘missing self’’ recognition of cells that downregulate MHC class I ...host MHC class I molecules impose an ‘‘educating impact’’ on ...
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Transport of Streptococcus pneumoniae capsular polysaccharide in MHC Class II tubules.
... (WT) mice with MHCII-GFP (I-Ea-EGFP) to investigate the presentation mechanism of ...assembled I-A and I-E molecules in transfected DCs was similar to I-A surface expression in ...
11
Functional deficiency of MHC class I enhances LTP and abolishes LTD in the nucleus accumbens of mice.
... experiment, mice were given intraperitoneal injections of either saline or cocaine (20 ...injections, mice were divided into groups that received seven daily injections of either saline or ...
8
Resident CD8(+) and migratory CD103(+) dendritic cells control CD8 T cell immunity during acute influenza infection.
... of MHC II during acute influenza infection. B6 mice were inoculated ...PKH26 or carrier 16 hours before ...anti-MHC II and analyzed on a flow ...of MHC II on the ...
7
Regulation of T cell response to leishmania antigens by determinants of histocompatibility leukocyte class I and II molecules
... class I molecules play a significant role in the regulation of the proliferation of T cells activated by mitogens and ...class I molecules to regulate T cell proliferation and interferon gamma (IFN- γ ) ...
8
Helper T cell epitope-mapping reveals MHC-peptide binding affinities that correlate with T helper cell responses to pneumococcal surface protein A.
... peptides or peptide libraries. Fortunately, the identification of MHC binding motifs allowed for the prediction of potential T cell epitopes ...silico MHC affinity measurement methods using both ...
16
Cathepsin B in antigen-presenting cells controls mediators of the Th1 immune response during Leishmania major infection.
... B-deficient mice express higher levels of MHC class II molecules in comparison with BMDC from cathepsin L-deficient and WT mice, but no differences were observed in the expression of ...
15
Polymorphisms in the F8 gene and MHC-II variants as risk factors for the development of inhibitory anti-factor VIII antibodies during the treatment of hemophilia a: a computational assessment.
... a MHC-II allele (for raw data see Table ...(4 or 5) were used around the position of each ...the MHC-II ...six MHC-II ...of MHC-II variants the peptide binds ...
11
Towards universal structure-based prediction of class II MHC epitopes for diverse allotypes.
... class I MHC, in which a peptide has only a single binding mode, a peptide can generally bind to class II MHC in multiple binding registers, each defined by which 9-mer segment of the complete ...
12
HLA class I and class II conserved extended haplotypes and their fragments or blocks in Mexicans: implications for the study of genetic diversity in admixed populations.
... of MHC class I (HLA-A, -B, -C), and class II (HLA-DRB1, -DQB1) genes using high-resolution sequence based typing (SBT) method and we structured the blocks and conserved extended haplotypes (CEHs) in ...
15
The role of MHC haplotypes H2d H2b in mouse resistancesusceptibility to cyst formation is influenced by the lineage of infective Toxoplasma gondii strain
... Type I/III genotype are associated with acquired ocular toxoplasmosis in ...a mice model to characterize some immunological mechanisms involved in host resistance to infection with such ...Type I/III ...
15
Mobilization of regulatory T cells in response to carotid injury does not influence subsequent neointima formation.
... 1996). Mice with a targeted deletion in the Tap1 gene (Tap1 0 ; ...of MHC class I molecules, mice deficient of the MHC class II genes H2-Ab1, H2- Aa, H2-Eb1, H2-Eb2 and H2-Ea (H2 ...
11
Patterns of MHC-G-Like and MHC-B Diversification in New World Monkeys.
... The MHC class I (MHC-I) region in New World monkeys (Platyrrhini) has remained relatively ...of MHC-I in Platyrrhini, we first analyzed public genomic sequences from the ...
20
Concepta McManus 1,3 , Samuel Rezende Paiva 2,3 , Ronyere Olegário de Araújo1
... In a study in the Federal District, McManus et al. (2009b) found that Morada Nova and Bergamasca had lowest Fecal Egg Count (FEC) for Strongylida, while lowest values for Strongyloides were found in Santa Inês and its ...
11
ATIVAÇÃO MICROGLIAL, LESÃO DA SUBSTÂNCIA BRANCA E EXPRESSÃO DE NOGO-A EM RATOS SUBMETIDOS À ISQUEMIA ESTRIATAL
... O objetivo desta investigação foi avaliar o padrão degenerativo de diversos tratos de substância branca após lesão isquêmica estriatal, correlacionando o processo degenerativo com os padrões de ativação microglial e ...
85
Loss of MHC and neutral variation in Peary caribou: genetic drift is not mitigated by balancing selection or exacerbated by MHC allele distributions.
... rare Mhc alleles prior to the collection of our historic samples, thus reducing our ability to detect high rates of loss of rare Mhc alleles and/or higher rates of loss variation at Mhc than ...
11
Expressão do complexo de histocompatilidade principal de classe I (MHC I) no sistema nervoso central: plasticidade sináptica e regeneração.
... classe I (MHC I), expres- so no sistema nervoso central (SNC), não funciona somente como molécula com papel imunológico, mas também como parte de um mecanismo en- volvido na plasticidade ...de ...
6
Preserved MHC class II antigen processing in monocytes from HIV-infected individuals.
... HIV or transfected to express specific HIV molecules such as Nef and Vpu ...virions or specific HIV products. These effects include inhibition of MHC-II expression, increase in invariant chain ...
7