multiple myeloma (MM)
MULTIPLE MYELOMA PRESENTING AS THIRD CRANIAL NERVE PALSY: A RARE CASE REPORT
... DISCUSSION: Plasmacytoma and multiple myeloma represents the spectrum of the same disease, where plasmacytoma refers to the localized form and MM implies systemic dissemination. The plasmacytoma may be ...
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Genetic aberrations in multiple myeloma characterized by cIg-FISH: a Brazilian context
... Genetic abnormalities are critical prognostic factors for patients diagnosed with multiple myeloma (MM). This retrospective, multicenter study aimed to contribute with the genetic and clinical ...
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Endothelial progenitor cells and associated pathways in multiple myeloma
... The bone marrow (BM) constitutes the primary site for haematopoiesis, a process through which blood cells are produced and the amount of each cell population that goes into circulation is regulated (Anthony and Link ...
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Cancer/Testis Antigen MAGE-C1/CT7: New Target for Multiple Myeloma Therapy
... with multiple myeloma must be distinguished from those with Monoclonal Gammopathy of Undetermined Significance (MGUS) (<10% plasma cells in bone marrow, low levels of M-protein (<3 g/dL), and no ...
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Silencing of augmenter of liver regeneration inhibited cell proliferation and triggered apoptosis in U266 human multiple myeloma cells
... Augmenter of liver regeneration (ALR) is a thermostable cytokine that was originally identified to promote the growth of hepatocytes. This study was conducted to explore the expression and function of ALR in ...
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The Role of Regulatory T Cells and TH17 Cells in Multiple Myeloma
... Multiple myeloma (MM) is a clonal B-cell malignancy char- acterized by an accumulation of mature plasma cells in the bone marrow, leading to bone destruction and failure of normal hematopoiesis ...
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ANKHD1 regulates cell cycle progression and proliferation in multiple myeloma cells
... Multiple myeloma (MM) is a hematologic malignancy charac- terized by the clonal proliferation of malignant plasma cells in the bone marrow [1–3]. Development of MM is a multistep process often associated ...
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The expression of p53 protein in patients with multiple myeloma
... Objective The aim of our study was to evaluate the clinical significance of p53 immunoexpression in multiple myeloma. Method A total of 58 patients with newly diagnosed MM (26 females and 32 males, mean age ...
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Multiple Myeloma in a Patient with Acromegaly
... Multiple myeloma (MM) is a malignant proliferative disease of monoclonal plasma cells that produce monoclonal immuno- globulins ...to myeloma involvement ...
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Plasmablastic multiple myeloma is associated with increased vascular endothelial growth factor immunoexpression
... aggressive multiple myeloma (MM) is associated with a more angio- genic marrow environment, bone marrow samples from 50 recently diagnosed MM patients were ...
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Pharmacovigilance of patients with multiple myeloma being treated with bortezomib andor thalidomide
... Multiple myeloma (MM) is a neoplasm with an unclear etiology, having an incidence of about 4 per 100,000, and accounting for 1% of all malignancies and 10% of hematologic malignancies ...
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Multiples aberrant phenotypes in multiple myeloma patient expressing CD56-, CD28+,CD19+
... in myeloma plasma cells (MPCs) is a common ...that multiple myeloma (MM) patients with CD56 negative MPCs present with aggressive disease and have a worse ...
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Double filtration plasmapheresis in a dog with multiple myeloma and hyperviscosity syndrome
... allergy, that may result from the exogenous plasma/ albumin transfusion (Lyu et al., 2002; Ismail et al., 2007; Kasuya et al., 2013). Moreover, the treatment requires a very short time (about two hours) and can be ...
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Multiple myeloma and central nervous system involvement: experience of a Brazilian center
... 1. Kyle RA. Monoclonal gammopathies of undetermined significance and smoldering multiple myeloma. In: Greer JP, Foerster J, Rodgers GM, Paraskevas F, Glader B, Arber DA, et al., editors. Wintrobe’s clinical ...
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Multiple myeloma with cells typically seen in storage diseases
... typical myeloma plasma cells and 20% of atypical large cells containing a great amount of azurophilic inclusions usually seen in storage diseases (Figure 1A and ...in multiple myeloma cells with most ...
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Peculiarities of bone metabolism in patients with multiple myeloma
... Multiple myeloma is one of the most widespread hemoblastosis. in the structure of oncohematology it takes up about 10%. it follows with destruction of bones and results in lethal outcome. ostealgiaґs ...
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BIOCHEMICAL PROFILE AND ELECTROPHORETIC PATTERN IN MULTIPLE MYELOMA PATIENTS
... RESULTS: Table 1 shows the biochemical profile of 94 diagnosed case of Multiple Myeloma. The mean Total protein in the diagnosed cases was 9.00±2.47gm/dL. Hyperproteinemia > 8.4gm/dL was seen in 62% ...
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Observational study of multiple myeloma in Latin America
... of multiple myeloma according to the International Myeloma Working Group criteria [8], and pa- tients with any plasma cell- or immunoglobulin-related disor- ders other than multiple ...
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Peripheral neuropathy in people with multiple myeloma
... with multiple myeloma, who were aged ...of multiple myeloma, 80% had symptoms of neuropathy before and/or during and/or after treatment with chemotherapy ...with multiple ...
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Primary systemic amyloidosis associated with multiple myeloma
... and multiple myeloma ...of multiple myeloma based on amyloid skin lesions, the patient was referred to the Hematology service and died 5 months after the ...
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